Results 1 to 10 of about 2,531 (114)

Clinical Outcomes of Immunosuppressant drugs in Patients Treated with Immune Checkpoint Inhibitors: A Systematic Review and Meta Analysis [PDF]

Medical Principles and Practice
Objectives: To systematically evaluate the impact of immunosuppressant drugs (ISDs) use on clinical outcomes in patients with cancer treated with Immune checkpoint inhibitors (ICIs). Methods: A systematic review and meta-analysis was conducted.
Faizah M. Alotaibi, Sara M. Alrowaydan, Lamia K. Alshamlani, Manar A. Alomar, Nora S. Almutairi, Seham A. Khashwayn, Kanan Alshammari, Jaffar A. Al-Tawfiq   +7 more
doaj   +2 more sources

Assessing Sun Protection Policies in Texas School Districts Located in Counties With the Lowest and Highest Melanoma Risk: Content Analysis and Cross-Sectional Study [PDF]

Cancer Control
Introduction School policy can encourage sun safe habits, such as wearing hats and applying sunscreen. However, sun safety policies (SSP) have not been formally assessed for Texas independent school districts (ISDs), particularly in counties with the ...
Nabeel Ahmad MD, MSEd, Brooke Bartley MD, Stephanie Zhang BS, Madison M. Taylor MD, Karl Schrader BS, Kehe Zhang MS, Hung Quoc Doan MD, PhD, Cici Bauer PhD, MS, Kelly C. Nelson MD, Jennifer Cofer DrPH, MPH, CHES   +9 more
doaj   +2 more sources

Increasing adverse event reports coincide with declining Medicare billings for interspinous devices [PDF]

North American Spine Society Journal
Background: ISDs treat spinal stenosis via a minimally invasive approach, but limited studies assess their efficacy and durability. The objective of this study was to characterize the incidence of adverse event reports (AERs) compared to Medicare claims ...
Aidan P. McAnena, BS, Taylor McClennen, BA, Raj J. Gala, MD   +2 more
doaj   +2 more sources

Microbial functions in skin inflammation: a Mendelian randomization study [PDF]

AMB Express
Inflammatory skin diseases (ISDs) represent a significant global health burden, yet the role of the human microbiome in their pathogenesis remains unclear.
Yujie Yang, Yiyuan Zhong, Peng Wu, MingXuan Li, Jingyi Cai, Qihong Chen, Xuwei Zheng, Haiming Chen, Teng Yu   +8 more
doaj   +2 more sources

A self-assembled nano-spray formulation for synergistic therapy of anti-inflammation and skin repair [PDF]

Asian Journal of Pharmaceutical Sciences
Inflammatory skin disorders (ISDs), characterized by severe inflammation and impaired skin barrier functions, often requires persistent treatment due to chronic and relapsing natures. To address these issues, we developed a small-molecular self-assembled
Qi Pan, Shiwei Zhang, Xiaojie Yan, Jiajing Guo, Bowen Li, Yuan Ping   +5 more
doaj   +2 more sources

Integrative Multi-Omics Analysis Reveals Critical Molecular Networks Linking Intestinal-System Diseases to Colorectal Cancer Progression [PDF]

Biomedicines
Background/Objectives: Colorectal cancer (CRC) frequently co-occurs with intestinal system diseases (ISDs), yet their molecular interplay remains poorly understood.
Shiliang Ji, Haoran Hu, Ruifang Zhu, Dongkai Guo, Yujing Liu, Yang Yang, Tian Li, Chen Zou, Yiguo Jiang, Guilai Liu   +9 more
doaj   +2 more sources

Use of Pharmacogenetics to Optimize Immunosuppressant Therapy in Kidney-Transplanted Patients

Biomedicines, 2022
Immunosuppressant drugs (ISDs) are routinely used in clinical practice to maintain organ transplant survival. However, these drugs are characterized by a restricted therapeutic index, a high inter- and intra-individual pharmacokinetic variability, and a ...
Valentina Urzì Brancati, Carmelo Scarpignato, Letteria Minutoli, Giovanni Pallio   +3 more
doaj   +1 more source

Is It Time to Say Farewell to the ISDS System?; Comment on “The Trans-Pacific Partnership: Is It Everything We Feared for Health?” [PDF]

International Journal of Health Policy and Management, 2017
Investor-state dispute settlement (ISDS) continues to plague health-oriented government regulation. This is particularly reflected in recent challenges to tobacco control measures through bilateral investment agreements.
Raphael Lencucha
doaj   +1 more source

Influence of In-Situ Oil Sands Development on Caribou (Rangifer tarandus) Movement. [PDF]

PLoS ONE, 2015
In-situ oil sands development (ISD) involves a network of facilities, wells, roads and pipelines to extract and transport subsurface bitumen. This technology is rapidly expanding and there is uncertainty whether ISDs restrict animal movement, leading to ...
Tyler Muhly, Robert Serrouya, Eric Neilson, Haitao Li, Stan Boutin   +4 more
doaj   +1 more source

JAK3 as an Emerging Target for Topical Treatment of Inflammatory Skin Diseases. [PDF]

PLoS ONE, 2016
The recent interest and elucidation of the JAK/STAT signaling pathway created new targets for the treatment of inflammatory skin diseases (ISDs). JAK inhibitors in oral and topical formulations have shown beneficial results in psoriasis and alopecia ...
Ana Karina Alves de Medeiros, Reinhart Speeckaert, Eline Desmet, Mireille Van Gele, Sofie De Schepper, Jo Lambert   +5 more
doaj   +1 more source