Results 31 to 40 of about 7,636 (305)
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Finite element modelling and load share analysis for involute worm gears with localised tooth contact [PDF]
, 2001 A new approach has been developed by the authors to estimate the load share of worm gear drives, and to calculate the instantaneous tooth meshing stiffness and loaded transmission errors. In the approach, the finite element (FE) modelling is based on the
Gentle, CR, Su, D, Yang, F
core
Dynamic characteristics of torus involute gear drive
, 2017 The torus involute gear drive originates from the involute spur gear drive, which is composed of a gear with convex teeth and the one with concave teeth. Previous researches of its mesh principle indicate that the torus involute gear can compensate large
Lei Liu +3 more
core +1 more source
Gear involute artifacts with sub-micron profile form deviations: manufacture and new design [PDF]
, 2023 Gear involute artifact (GIA) is a kind of calibration standard used for traceability of involute metrology. To machine GIAs with sub-micron profile form deviations, the effect on the involute profile deviations caused by the geometric deviations and 6 ...
Dianqing Yu +5 more
core +2 more sources
Rigged configurations and the $$*$$-involution [PDF]
Letters in Mathematical Physics, 2018 20 pages; updated grant information for ...
Ben Salisbury, Travis Scrimshaw
openaire +5 more sources
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
On framed involute-evolute curve pairs [PDF]
, 2023 Bu çalışma dört bölümden oluşmuştur. Birinci bölüm giriş kısmına ayrılmıştır. İkinci bölümde Öklid uzayı ve çatılandırılmış eğriler ile ilgili temel kavramlara yer verilmiştir.
Gürsaç, Ebru
core +1 more source
FEBS Open Bio, EarlyView.We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source
Development of a Hybrid Involute Gear Profile
, 2009 To achieve a gearset which will maintain the beneficial properties of using involute shaped teeth, while allowing the gear ratio to vary, a new gear profile has been identified.
Robert H. Todd +2 more
core +1 more source