Results 141 to 150 of about 135,456 (314)

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

Metabolic involutions

open access: yesJournal of Algebra, 2011
AbstractIn this paper we study the conditions under which an involution becomes metabolic over a quadratic field extension. We characterise those involutions that become metabolic over a given separable quadratic extension. We further give an example of an anisotropic orthogonal involution that becomes isotropic over a separable quadratic extension.
openaire   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Determination of an unknown source term temperature distribution for the sub-diffusion equation at the initial and final data

open access: yesElectronic Journal of Differential Equations, 2017
We consider a class of problems modeling the process of determining the temperature and density of nonlocal sub-diffusion sources given by initial and finite temperature.
Mokhtar Kirane   +2 more
doaj  

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

open access: yesFEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel   +2 more
wiley   +1 more source

Product involutions with 0 or 1-dimensional fixed point sets on orientable handlebodies

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1994
Let h be an involution with a 0 or 1-dimensional fixed point set on an orientable handlebody M. We show that obvious necessary conditions for fibering M as A×I so that h=τ×r with τ an involution of A and r reflection about the midpoint of I also turn out
Roger B. Nelson
doaj   +1 more source

Equational theories of unstable involution semigroups

open access: yes, 2017
It is long known that with respect to the property of having a finitely axiomatizable equational theory, there is no relationship between a general involution semigroup and its semigroup reduct.
Edmond W. H. Lee
semanticscholar   +1 more source

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