Results 61 to 70 of about 134,982 (117)

Real-world short-term outcomes and treatment regimen comparisons in patients with metastatic renal cell carcinoma treated with first-line immune combinations

BMC Cancer
Background Immune-combinations have recently become the standard first-line treatment for patients with metastatic renal cell carcinoma (mRCC). This study evaluated the applicability of the International Metastatic Renal Cell Carcinoma Database ...
Masato Kikuta, Sei Naito, Takahiro Osawa, Kazuyuki Numakura, Takafumi Narisawa, Yuki Takai, Mayu Yagi, Yuya Sekine, Ojiro Tokairin, Nobuo Shinohara, Tomonori Habuchi, Norihiko Tsuchiya   +11 more
doaj   +1 more source

Meteoceanographic Patterns Associated with Severe Coastal Storms Along the Southern Coast of Brazil

Meteorology
Extratropical cyclones are the main drivers of high-energy wave events along the southern coast of Brazil, frequently producing hazardous coastal conditions.
Larissa de Paula Miranda, Jeferson Prietsch Machado, Jaci Bilhalva Saraiva, Débora Gadelha de Barros, Elaine Siqueira Goulart, Hugo Nunes Andrade   +5 more
doaj   +1 more source

Comparative efficacy of immune checkpoint inhibitor combination therapies by metastatic site in metastatic renal cell carcinoma

Scientific Reports
Few studies have investigated the efficacy of immuno-oncology (IO) combinations at different metastatic sites in renal cell carcinoma (RCC). We evaluated the differential efficacy of IO–IO and IO–tyrosine kinase inhibitor (TKI) combinations by metastatic
Shingo Toyoda, Lan Inoki, Mamoru Hashimoto, Wataru Fukuokaya, Keiichiro Mori, Shingo Nishimura, Ryoichi Maenosono, Takehiro Iwata, Kensuke Bekku, Takuhisa Nukaya, Takafumi Yanagisawa, Takuya Tsujino, Kazumasa Komura, Kiyoshi Takahara, Teruo Inamoto, Haruhito Azuma, Kazutoshi Fujita, JK-FOOT study group   +17 more
doaj   +1 more source

Impact of high relative dose intensity on effectiveness and treatment continuity of IO-TKI therapy in Japanese advanced renal cell carcinoma

Scientific Reports
This study investigated the impact of relative dose intensity (RDI) on the effectiveness and safety of immuno-oncology plus tyrosine kinase inhibitor (IO-TKI) therapy in Japanese patients with renal cell carcinoma (RCC). A total of 145 patients receiving
Yoshihiko Tasaki, Shuzo Hamamoto, Hiroaki Ikoma, Misato Tomita, Takuya Sakata, Hiroko Suzuki, Yusuke Noda, Masayuki Usami, Yohei Tsubouchi, Toshiharu Morikawa, Yoshihisa Mimura, Yosuke Sugiyama, Takashi Nagai, Rei Unno, Toshiki Etani, Taku Naiki, Yoko Furukawa-Hibi, Takahiro Yasui   +17 more
doaj   +1 more source

A simple computational model for scleral stiffness assessments via air-puff deformation OCT

Frontiers in Bioengineering and Biotechnology
Introduction: The mechanical properties of the sclera are related to its structural function, and changes to these properties are believed to contribute to pathologies such as myopia.
Andres De La Hoz, Lupe Villegas, Susana Marcos, Judith S. Birkenfeld   +3 more
doaj   +1 more source

Efficacy of immune-oncology combinations versus sunitinib in patients with bone metastases from renal cell carcinoma: A systematic review and meta-analysis of phase III trials with long-term follow-up. [PDF]

J Bone Oncol
de Albuquerque CFA, Reis LCS, Manna EDF, Zafalon AES, Yabrude ATZ, Porta C.   +5 more
europepmc   +1 more source

Comparable efficacy of extraoral and intraoral photobiomodulation in preventing oral mucositis during high-dose methotrexate therapy in pediatric oncology: A single-blind randomized controlled trial. [PDF]

Support Care Cancer
Freitas IOP, Schuartz I, Renz GLK, Mobile RZ, França MLS, Pianovski MAD, Sassi LM, de Araujo MR.   +7 more
europepmc   +1 more source

Xylose-Assisted Glycolic Acid Overproduction in Engineered <i>Issatchenkia orientalis</i>. [PDF]

J Fungi (Basel)
Ge R, Wang X, Xing Y, Yu D, Hu L, Xu Z, Wu Q, Zhu D, Cao M.   +8 more
europepmc   +1 more source

Comparative Analysis of Silk Fibroin Membranes across Cross-Linking Methods: Processing and Characterization

ACS Omega
Rocio Gutierrez-Contreras, Mar Fernandez-Gutierrez, Paula Olalla-Perez, Andres De La Hoz, Susana Marcos   +4 more
doaj   +1 more source

Comparative effectiveness of neoadjuvant treatment strategies and predictors of pathological complete response in locally advanced esophageal squamous cell carcinoma: a real-world retrospective cohort study. [PDF]

Front Oncol
Yuan X, Liang Y, Han T, Guo Z, Sun Y, Dong Y, Zhang L, Li H, Li J, Sun X, Liu H.   +10 more
europepmc   +1 more source