Results 51 to 60 of about 19,021,115 (262)

Engineering Concentration‐Dependent Intravitreal Mobility via Cyclic Arginine‐Enriched Nanocarrier Surface Modification: In Vivo Proof‐of‐Concept in a Porcine Large Animal Model

Advanced Healthcare Materials, EarlyView.
In this study, Hammer et al. highlight cyclic‐arginine surface engineering as a highly biocompatible, controllable, and concentration‐dependent regulator of intravitreal nanoparticle mobility in vivo in a translational large animal model. The cyclic arginine surface‐modification supports the development of next‐generation biomaterials for long‐acting ...
Maximilian Hammer, Bryan Calder Ackermann, Anna Stoß, Niklas Junker, Ludwig Geisweid, Sabrina Wohlfart, Jonathan Herth, Simon William Pohl, Manuel Ben Böhmann, André Schulz, Victor Aristide Augustin, Gerd Uwe Auffarth, Philipp Uhl   +12 more
wiley   +1 more source

The presence of iodinated contrast agents amplifies DNA radiation damage in computed tomography

, 2011
The purpose of this study was to determine the influence of iodinated contrast agents on the formation of DNA double-strand breaks in vitro in lymphocytes and to verify these results in patients undergoing diagnostic computed tomography examinations ...
Klaus J. Klose, Johannes T. Heverhagen, Voelker, Maximilian, Caroline Pathe, Klose, Klaus J, Bjoern Kaestner, Pathe, Caroline, Eble, Katharina, Heverhagen, Johannes T, Kaestner, Bjoern, Maximilian Voelker, Daniel Schmitz-Beuting, Kleb, Beate, Schmitz-Beuting, Daniel, Katharina Eble, Keil, Boris, Beate Kleb, Boris Keil   +17 more
core   +1 more source

Coronary Angiography with Gadolinium in Patients with Severe Allergy to Iodinated Contrast Media [PDF]

, 2012
The use of iodinated contrast media is contraindicated in some patients due to serious life-threatening adverse events. In such cases, there are reports that gadolinium (gadobutrol), which is commonly employed in magnetic resonance imaging, may be used ...
Meireles, George César Ximenes, Kreimer, Sérgio, Marchiori, Gilberto Guilherme Ajjar, Scanavacca, Rafael, Galon, Micheli Zanotti   +4 more
core   +1 more source

Water‐Activated Phospholipid Phase‐Separation Gel as an Immunomodulatory Anti‐Adhesion Barrier for Postoperative Adhesion Prevention

Advanced Healthcare Materials, EarlyView.
A water‐activated phospholipid phase‐separation gel is repurposed as a drug‐free surgical barrier for postoperative adhesion prevention. Propylene glycol promotes rapid lamellar gel reinforcement, prolonged local retention, and tissue coverage, while phosphatidylcholine‐mediated immunomodulation suppresses inflammatory and fibrotic responses. This dual‐
Jong‐Ju Lee, Yulseung Sung, Yeji Kim, Heesang Yang, Suyeon Pyo, Byeol Yun, Sung‐Joo Hwang   +6 more
wiley   +1 more source

Computed Tomography‐ and Photoacoustic Imaging‐Active Bioresorbable Electrospun Bismuth Nanoparticle‐Infused Small‐Diameter Vascular Grafts

Advanced Healthcare Materials, EarlyView.
A polymeric graft loaded with radiopaque bismuth nanoparticles is expected to undergo gradual polymer resorption and nanoparticle release. This design enables noninvasive, multimodal monitoring of device integrity, patency, and degradation using computed tomography alongside ultrasound and photoacoustic imaging over 12 weeks.
Allan John R. Barcena, Joy Vanessa D. Perez, Marvin R. Bernardino, Dominic Karl M. Bolinas, Kitz Paul D. Marco, Kim Claudette J. Fernandez, Archana Mishra, Erin Marie D. San Valentin, Jossana A. Damasco, Gino Martin Canlas, Natalie Fowlkes, Richard R. Bouchard, Steven Y. Huang, Marites P. Melancon   +13 more
wiley   +1 more source

Processing-dependent and -independent pathways for recognition of iodinated contrast media by specific human T cells

, 2010
One to three percent of patients exposed to intravenously injected iodinated contrast media (CM) develop delayed hypersensitivity reactions. Positive patch test reactions, immunohistological findings, and CM-specific proliferation of T cells in vitro ...
Kanny, G., Keller, M, Lochmatter, P, Bircher, A J, Keller, M., A. J. Bircher, Britschgi, M., Gerber, B. O., Pichler, W. J., Pichler, W J, W. J. Pichler, G. Kanny, Christiansen, C., Lüthi, M., Christiansen, C, P. Lochmatter, Lochmatter, P., C. Christiansen, Kanny, G, Lerch, M, Lüthi, M, M. Britschgi, Tâche, V, Bircher, A. J., V. Tâche, M. Lerch, Gerber, B O, M. Lüthi, Britschgi, M, B. O. Gerber, M. Keller, Lerch, M., Tâche, V.   +32 more
core   +1 more source

Directing Near‐Perfect (001) Orientation in Wafer‐Scale BiOI Thin Films via Halide‐Mediated van der Waals Stacking

Advanced Materials, EarlyView.
Our work introduces a new framework that fundamentally changes how orientation in bismuth oxyhalide systems is approached. Comprehensive experiments, backed by theoretical models, reveal the pivotal role of halide anions to modify the van der Waals stacking energies required to direct orientation. Our method enables the fabrication of near perfect (001)
Gabriel Aygur, Ashakiran Maibam, Hayden Tuohey, Tony Nguyen, Mei Xian Low, Sumeet Walia, Zijun (June) Yong, Ravichandar Babarao, Daniel Gomez, Enrico Della Gaspera, Joel van Embden   +10 more
wiley   +1 more source

Comprehensive literature review of oral and intravenous contrast-enhanced PET/CT: a step forward?

Frontiers in Medicine
The integration of diagnostic CT scans into PET/CT facilitates a comprehensive single examination, presenting potential advantages for patients seeking a thorough one-shot check-up.
Gilles Metrard, Gilles Metrard, Clara Cohen, Matthieu Bailly, Matthieu Bailly   +4 more
doaj   +1 more source

Self‐Assembling Copolymers Encapsulating Single Endothelial Cells Induce Endogenous ECM Deposition and Vascular Regeneration

Advanced Materials, EarlyView.
This study presents the first demonstration of stable sub‐50‐micron single‐cell GPM vesicles fabricated through the intrinsic self‐assembly of an amphiphilic copolymer. Hierarchical assembly of cell containing GPM vesicles into microspheres enable tunable, sustained cell delivery with immune protection.
Viola B. Morris, Sangho Lee, Kalp Soni, Simon He, Matthew Huang, Dandan Chen, Dae Hoon Lee, Kyung Hee Kim, Seonggeon Cho, Laura Pencea, Divit Jain, Young‐Sup Yoon   +11 more
wiley   +1 more source

Patients at risk for contrast-induced acute kidney injury

Italian Journal of Medicine, 2013
Subjects with hypovolemia and/or dehydration and pre-existing renal failure are considered at highest risk for radiocontrast-medium-induced acute kidney injury (RCI-AKI), and this risk increases in the presence of glomerular filtration rate or creatinine
Michele Meschi, Simona Detrenis, Marcella Saccò, Marcello Bertorelli, Enrico Fiaccadori, Alberto Caiazza, Giorgio Savazzi   +6 more
doaj   +1 more source