Results 161 to 170 of about 32,086 (240)

Burden attributable to Iodine deficiency in Iran from 1990 to 2019: findings from Global Burden of Disease study. [PDF]

J Prev Med Hyg
Rasoulian P, Khadembashiri MA, Amlashi MA, Ghazanfari S, Arbatan MN, Rabiei Z, Danandeh K, Faridpour A, Dehghani E.   +8 more
europepmc   +1 more source

Stereoretentive Nucleophilic Aromatic Substitution Accesses Atropisomeric 4‐Amino‐N‐Arylquinolinium Salts

Chemistry – A European Journal, EarlyView.
Quinolin‐4‐ones were converted to chloroquinolinium salts, allowing formation of axially chiral aminoquinolinium salts via an enantioretentive SNAr reaction with a variety of amine nucleophiles. The salts have a high rotational barrier, with a racemization half‐life of ∼1000s of years.
Darren Holmes, Nia Foster, Saima Ansari, Paul Kavanagh, Paul Dingwall, Peter C. Knipe   +5 more
wiley   +1 more source

Evaluating iodine deficiency and goiter in hilly areas of District Poonch Azad Jammu Kashmir. [PDF]

Pak J Med Sci
Khaliq A, Fayaz M, Hayat I, Abbas M.
europepmc   +1 more source

Extracellularly Activatable Conjugates of RGD Peptidomimetics and Cryptophycin for αVβ3‐Targeted Cancer Therapy

Chemistry – A European Journal, EarlyView.
Integrin αVβ3‐targeting small‐molecule drug conjugates (SMDCs) were synthesized by conjugating a cryptophycin payload through a neutrophil elastase‐cleavable NPV‐PABC linker. RGD peptidomimetic and linker epimers served as controls for targeting and enzymatic cleavage, and the resulting conjugates displayed subnanomolar cytotoxicity in vitro.
Dominic Seißenschmidt, Henriette Hartung, Jonah Kammer, Norbert Sewald   +3 more
wiley   +1 more source

Synthesis of Oligonucleotide Conjugates Employing a Diselenide Linker

Chemistry – A European Journal, EarlyView.
ABSTRACT In this study, we report the synthesis of an alkylene linker containing a terminal 2‐cyanoethyl protected selenium functionality for coupling at the 5'‐end of an oligonucleotide by solid phase synthesis for the preparation of oligonucleotide conjugates.
Shivam Tikoo, Anne M. Noronha, Christopher J. Wilds   +2 more
wiley   +1 more source

Does the island area also need to insist on salt iodization to prevent iodine deficiency disorders? a cross-sectional survey in Hainan Province, China. [PDF]

Front Endocrinol (Lausanne)
Wu H, Meng S, Sun D, Hu Y, Wu T, Wang X, Wang X, Liu Y, Peng C, He B, Meng F.   +10 more
europepmc   +1 more source

Nitrooxylation in Organic Synthesis: From Classical Nitrate Ester Formation to Modern Catalytic Strategies

Chemistry – A European Journal, EarlyView.
Nitrooxylation—the installation of nitrate esters (–ONO2) has evolved from classical mixed‐acid protocols to catalytic and mechano‐, flow‐, photo‐, and electrochemical strategies. This review delineates ionic and radical manifolds for C–ONO2 bond formation, emphasizing mechanistic control, selected substrate scope, and selectivity.
Jayanta Dey, Dmitry Katayev
wiley   +1 more source

Trends in three malnutrition factors in the global burden of disease: iodine deficiency, vitamin A deficiency, and protein-energy malnutrition (1990-2019). [PDF]

Front Nutr
Ji S, Zhou Y, Zhao Q, Chen R, Su Z.
europepmc   +1 more source

Expanding Cyanide‐Bridged Weakly Coordinating Anions Through the Brominated Silver Salt Ag[BCNBBr]

Chemistry – A European Journal, EarlyView.
The brominated weakly coordinating anion [μ‐(CN)(B(C6F4Br)3)2] ([BCNBBr]−), based on two B(C6F4Br)3 units bridged by cyanide, is obtained as its silver salt Ag[BCNBBr] from CH2Cl2. Ag[BCNBBr] enables oxidation and halide abstraction reactions, affording diverse [BCNBBr]− salts with oxidizing and electrophilic cations.
Amina L. Moshtaha, Tim‐Niclas Streit, Joshua Parche, Robin Sievers, Moritz Malischewski   +4 more
wiley   +1 more source

Detecting iodine deficiency risks from dietary transitions using shopping data. [PDF]

Sci Rep
Mansilla R, Long G, Welham S, Harvey J, Lukinova E, Nica-Avram G, Smith G, Salt D, Smith A, Goulding J.   +9 more
europepmc   +1 more source