Results 61 to 70 of about 537,384 (235)

RPLP2 Mediates the Beneficial Effects of Exercise on Stress Resistance Through Muscle–Brain Communication

open access: yesAdvanced Science, EarlyView.
A novel exercise‐inducible myokine acidic ribosomal protein P2 (RPLP2), initially identified from human trials, is presented here, whose circulating levels negatively correlate with clinical anxiety severity. Muscle‐derived RPLP2 enhances hippocampal ribosomal assembly and adult neurogenesis to rescue stress‐induced anxiety deficits.
Peiyu Luo   +18 more
wiley   +1 more source

Iodine value in pregravidal period of a woman’s life [PDF]

open access: yesГинекология, 2014
Iodine is an essential trace element, which is essential for the formation and development of a complete organism. Attempts to eliminate iodine deficiency are reduced to mass prevention by iodination of certain foods, but it is not possible to prevent ...
R M Yesayan, A V Sekinaeva
doaj  

CALB2 is a Mechanoresistance Gene in Metastatic Prostate Cancer

open access: yesAdvanced Science, EarlyView.
Prostate cancer cell lines of differing origins were cultured over many passages while being subjected to semi‐lethal levels of fluid shear stress, representing the harsh mechanical environment these cells are subjected to in the circulation during the process of distant metastasis.
Abigail R. Fabiano   +10 more
wiley   +1 more source

Rewiring Pyroptosis to Potentiate Cancer Immunotherapy via a Gasdermin D Agonist Bypassing Caspase‐3

open access: yesAdvanced Science, EarlyView.
This work introduces a small‐molecule agonist, DIBDO, that bypasses Casp‐3 to directly trigger GSDMD‐mediated pyroptosis in tumors. Activated by glutathione, DIBDO generates singlet oxygen and molecular iodine, blocking Casp‐3 pathways and inducing immunogenic cell death.
Dan Zhao   +6 more
wiley   +1 more source

Are fluoride levels in drinking water associated with hypothyroidism prevalence in England? A large observational study of GP practice data and fluoride levels in drinking water [PDF]

open access: yes, 2015
Background While previous research has suggested that there is an association between fluoride ingestion and the incidence of hypothyroidism, few population level studies have been undertaken.
Spencer, S   +5 more
core   +2 more sources

A Supramolecular Thermal Switch for Precision Pyroptosis via Host−Guest Recognition and Electrostatic Interactions

open access: yesAdvanced Science, EarlyView.
A supramolecular pyroptotic thermal switch encapsulates I3− within β‐cyclodextrin (β‐CD) and undergoes CaCO3 mineralization. Upon lysosomal acidification, CaCO3 is degraded, releasing Ca2+ and I3−. Concurrently, BODIPY activation converts I3− into I2, inducing oxidative stress and Ca2+ overload, which together trigger caspase‐3/GSDME‐mediated ...
Dan Wu   +8 more
wiley   +1 more source

The Status of Iodine and Selenium in Waikato Soils [PDF]

open access: yes, 2011
This thesis investigates the status of the essential trace elements iodine and selenium in Waikato soils. Soil samples (368) representing different Soil Orders, land uses and soil depths were examined.
McNally, Samuel Rae
core  

N–O Dual Functional Group Transposition via Energy Transfer Photocatalysis

open access: yesAdvanced Science, EarlyView.
N–O dual functional group transposition (dFGT) enabled by the photocatalytic energy transfer (EnT) has been developed. This methodology is applicable to both activated and unactivated alkyl derivatives for dFGT, and it also successfully extended to N–N dFGT, demonstrating its general applicability.
Lei Bao   +4 more
wiley   +1 more source

An assessment of urinary Iodine and serum TSH concentration in pregnant women referred to Deziani Hospital in Gorgan, Iran, 2004

open access: yesمجله دانشگاه علوم پزشکی گرگان, 2004
Background & Objective: No nutrient deficiency is as bad as Iodine deficiency which attributed to a broad spectrum of disorders like goiter, abortion, hypothyroidism, etc. Screening for hypothyroidism must be done before or just after pregnancy.
S.Bakhshandeh-Nosrat (M.D)   +3 more
doaj  

The Cognitive Link Between Geography and Development: Iodine Deficiency and Schooling Attainment in Tanzania [PDF]

open access: yes
An estimated 20 million children born each year are at risk of brain damage from in utero iodine deficiency, the only micronutrient deficiency known to have significant, non-reversible effects on cognitive development.
Máximo Torero   +2 more
core  

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