Results 81 to 90 of about 31,512 (243)

Quantitative Mass Spectrometry‐Based Biodistribution of Monoclonal Antibodies: An Alternative to Radio‐Biodistribution

Advanced Science, EarlyView.
Monoclonal antibodies are powerful anticancer therapeutics targeting tumor‐associated antigens. Mass spectrometry enables precise and accurate quantification of mAbs in tumor plasma and healthy organs. Unlike ligand binding assay and radioactivity, mass spectrometry does not suffer from matrix effects and labelling artefacts while facilitating method ...
Domenico Ravazza, Sheila Dakhel Plaza, Samuele Cazzamalli, Andrea Ciamarone, Andrea Galbiati, Riccardo Stucchi, Frederik Peissert, Emanuele Puca, Dario Neri, Ettore Gilardoni   +9 more
wiley   +1 more source

Novel Vascular‐Adaptive Liquid Metal Microspheres Enable Visualized Arterial Embolization Therapy

Advanced Science, EarlyView.
We present drug‐loaded liquid metal microspheres (X‐MEN) as a novel agent for image‐guided arterial embolization. With inherent radiopacity and superior deformability, X‐MEN enables real‐time monitoring and conforms tightly to irregular vessels. This approach ensures precise, long‐lasting embolization without recanalization, addressing critical ...
Chenyu Shen, Junge Chen, Gang Zhang, Zhusheng Liu, Yichen Wan, Lei Lei, Weiyan Ren, Yanyu Zhao, Bozhang Xia, Zhiqiang Yi, Jinjin Wang, Jingwang Gao, Gen Mu, Xing‐Jie Liang, Zhijun Wang   +14 more
wiley   +1 more source

Smartly Assembled near‐Micron RF‐Responsive Agents Bridge Transarterial Embolization and Immunothermal Potentiation

Advanced Science, EarlyView.
ABSTRACT Hepatocellular carcinoma (HCC) remains a significant clinical challenge due to the limited efficacy of conventional treatments like surgery, radiofrequency ablation (RFA), and transarterial embolization (TAE). Here, we develop an innovative TAE and immunothermal therapy strategy based on smartly assembled near‐micron layered double hydroxide ...
Qitao Hu, Junkang Ding, Lingxiao Zhang, Zhou Tian, Cheng Zeng, Shaomin Zou, Wenjing Zhang, Tangye Zeng, Zhencang Gao, Zhouyi Sun, Gang Liu, Weiyu Chen, Zhe Tang   +12 more
wiley   +1 more source

The role of iodine in thyroid function and iodine impact on the course of Hashimoto’s thyroiditis - review

Quality in Sport
Introduction: Iodine is one of the most important micronutrients necessary for the proper functioning of the thyroid gland. It is an essential component of thyroxine and triiodothyronine, hormones produced and secreted by the thyroid gland.
Zuzanna Malinka, Julita Gmitrzuk, Katarzyna Wiśniewska, Anna Jachymek, Martyna Opatowska, Joanna Jakubiec, Tomasz Kucharski, Marta Piotrowska   +7 more
doaj   +1 more source

Diffusion‐Driven Targeted Passivation of Selenium Vacancies via an I‐Doped CdS Buffer Layer for Efficient Sb2Se3 Solar Cells

Advanced Science, EarlyView.
Iodine incorporation into the CdS buffer layer induces spontaneous anion diffusion and selectively passivates selenium vacancies in Sb2Se3 absorbers. The formation of low‐energy, charge‐neutral ISe defects effectively suppresses non‐radiative recombination, resulting in a substantially enhanced open‐circuit voltage and boosting the device efficiency to
Luyan Shen, Deyang Qin, Er Nie, Jiahua Tao, Hidefumi Akiyama, Junhao Chu, Shaoqiang Chen   +6 more
wiley   +1 more source

Engineered Interfacial Control for Suppression of Phase Instability: Operando Visualization from Device to Module Scale

Advanced Science, EarlyView.
Operando real‐time current density–voltage absorption spectroscopy visualizes spatial phase evolution in mixed‐halide perovskites from device to module scale. Phase instability preferentially initiates in regions with insufficient carrier extraction, revealing electrical boundary conditions as governing factors.
Hangyeol Choi, Soo Woong Jeon, Wookyung Jeon, You‐Hyun Seo, Gill Sang Han, Myunghun Shin, Ji‐Sang Park, Jun Hong Noh, Yohan Yoon   +8 more
wiley   +1 more source

Redox‐Active Tungsten Mono‐Oxo Bis(dithiolene) Complex: A Fast‐Rechargeable Anode for High‐Capacity Lithium‐Ion Batteries

Advanced Science, EarlyView.
This study reports the first application of a W‐oxo bis(dithiolene) complex, (Et4N)2[WO(S2C2(C6H5)2)2], as a novel anode material for lithium‐ion batteries. This complex stores Li+ ions via multivalent W‐centered redox processes involving its oxo (WO) and dithiolene (S) sites.
Honggyu Seong, Jaeheon Lee, Jae Hyun Park, Woonghee Lee, Junhyeok Seo, Jaewon Choi   +5 more
wiley   +1 more source

Soft and Adhesive Cardiac Patch for Electrophysiological and Contraction Measurement

Advanced Science, EarlyView.
This study developed an epicardial electronic patch with a modulus similar to that of the heart (approximately 65kPa), which can collect stable electrocardiogram signals and myocardial contractility on the surface of a dynamically beating heart. This is attributed to the hydrogen bond interaction formed between the amino and catechol groups in the ...
Wuliang Chen, Xinyu Shen, Hanning Liu, Lamei Du, Caicai Jiao, Longfei Li, Qian Wang, Qiuting Zhang, Lixue Tang, Liang Hu, Yubo Fan   +10 more
wiley   +1 more source

Sono‐Mechanogenetics: Linking Ultrasound Physics With Cellular Mechanobiology

Advanced Science, EarlyView.
Sono‐mechanogenetics links ultrasound physics with cellular mechanotransduction to enable noninvasive control of engineered biological systems. Acoustic forces generate distinct deformation modes that activate intracellular signaling pathways, which can be coupled to synthetic gene circuits to regulate diverse cellular functions, including gene ...
Yunjia Qu, Fan Wei, Chi Woo Yoon, Qifa Zhou, Yingxiao Wang   +4 more
wiley   +1 more source

Solution‐Processed Nickel Oxide as Efficient Hole Transport Layers in Inverted Perovskite Solar Cells

Advanced Science, EarlyView.
This review summarizes recent advances in four mainstream solution‐based techniques for synthesizing NiOx hole‐transport layers for high‐performance perovskite photovoltaic cells, and highlights the key challenges and future prospects for achieving high efficiency, long‐term stability, and low‐cost perovskite photovoltaic technologies toward ...
Zheng Wu, Zeliang Qiu, Yuxin Tao, Yuyang Qiu, Yuwei Duan, Jianxing Xia, Feng Li, Qiang Peng   +7 more
wiley   +1 more source