Results 91 to 100 of about 537,384 (235)

Medico-social effectiveness of biological monitoring of iodine deficiency status (IDS) among women of reproductive age in Kazakhstan

, 2019
Introduction Iodine deficiency is one of the most important public health problems in the world. It mostly affects pregnant women and children. The lack of iodine leads to an increase in the numbers of perinatal mortality and mental retardation ...
Aizhan Raushanova, Konrad Juszkiewicz, Gulstan Khassenova, Maikul Kainarbayeva, Ardak Chuyenbekova, Arailym Beisbekova, Aigul Kozhakhmetova, Dinara Kenessary   +7 more
core   +1 more source

Microfluidic Gratings for X‐Ray Phase Contrast Imaging

Advanced Science, EarlyView.
This work establishes a new protocol for the fabrication of X‐ray gratings that exploits the advantages of microfluidics and enables a more inexpensive, faster, and scalable production process. These X‐ray devices are fundamental for implementing X‐ray phase contrast imaging (XPCI) in laboratory and clinical settings, yet their costly and complex ...
Alessandro Rossi, Antonio Ferraro, Francesco Coccimiglio, Tiziana Ritacco, Alberto Astolfo, Michele Giocondo, Vincenzo Formoso, Raffaele Giuseppe Agostino, Francesco Iacoviello, Ioannis Papakonstantinou, Alessandro Olivo   +10 more
wiley   +1 more source

Macrophage Dab1 Links Early Hypoxia to Adaptive Angiogenesis to Drive Peripheral Nerve Repair

Advanced Science, EarlyView.
Schematic diagram illustrating the Dab1‐linked hypoxia signaling pathway that accelerates angiogenesis and consequent nerve regeneration. Following PNI, a hypoxic microenvironment develops. Hypoxia induces macrophage Dab1 phosphorylation, resulting in NHE‐1 upregulation, HIF‐1α stabilization, and VEGF‐A expression. This cascade promotes angiogenesis in
Xiongyao Zhou, Fan Zhang, Jiangbo Wang, Huiyuan Wang, Zongqiang Wang, Qianqian Wang, Chuikai Meng, Jialu Sun, Han Wang, Weiye Li, Ziyi Zhao, Le Qi, Xiaosong Gu, Shusen Cui, Rangjuan Cao   +14 more
wiley   +1 more source

The Effects of Hypothyroidism Due to Iodine Deficiency in Neonatal Brain

, 2009
Most studies show that iodine deficiency and maternal-fetal hypothyroxinemia have negative effects on fetal neural maturation, dendritic arborization and synaptic formation.
Hakki Muammer Karakaş, KarakaŞ H.M., Ayşehan Akinci, Akinci A.   +3 more
core   +1 more source

A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior

Advanced Science, EarlyView.
Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li, Ying‐Dan Zhang, Wei Wang, Xin‐Yi Wu, Di Li, Xin Gong, Fei Tian, Meng‐Yu Dai, Jian Gao, Zi‐Feng Zheng, Zi‐Yang Bi, Dong‐Dong Shi, Zhen Wang   +12 more
wiley   +1 more source

PROPHYLACTICS OF IODINE DEFICIENCY DISEASES

Педиатрическая фармакология, 2008
This article covers a relevant problem of modern medicine — that of iodine deficiency, which results in derangement of all vital process in the body, decreasing the intellectual and physical development of a child.
L.S. Namazova, I.V. Shirokova
doaj   +2 more sources

The predictive value of the urinary iodine-to-creatine ratio in spot samples for the estimation of 24-hour urinary iodine excretion in adult non-pregnant women

Frontiers in Endocrinology
ObjectiveThe study aimed to compare iodine-to-creatinine ratios in morning spot samples with 24-hour iodine excretion, serving as the reference standard in adult non-pregnant women.
Jerzy Chudek, Joanna Fryżewska, Piotr Kocełak, Aleksander J. Owczarek, Piotr Mikuła, Anna Chudek, Anna Chudek, Joanna Staniszewska-Mróz, Mateusz Winder, Magdalena Olszanecka-Glinianowicz, Gabriela A. Handzlik   +10 more
doaj   +1 more source

Cannabinoid CB1 Receptor in Nociceptors Mediates Postoperative Analgesia via ASIC3 Inhibition

Advanced Science, EarlyView.
CB1R and ASIC3 are co‐expressed in CGRP+ nociceptors of mouse DRG. Plantar incision triggers an upregulation of ASIC3 and activation of ASIC3+ neurons, driving mechanical allodynia. CB1R activation suppresses ASIC3 function and downstream ERK1/2 phosphorylation, thereby braking nociceptive signaling and accelerating pain resolution.
Kangtai Xu, Luyao Ji, Haoyi Yang, Xiying Chen, Qiaodan Hu, Haimei He, Jiawei Wu, Leyan Shan, Shihui Feng, Yingzhi Li, Xiongchang Tan, Hao Wang, Zilong Wang, Chaoran Wu   +13 more
wiley   +1 more source

Current iodine status and progress over the last decade towards elimination of iodine deficiency in Rajkot District, Gujarat [PDF]

, 2009
Objective: To find out prevalence of goitre in primary school children; to compare prevalence with previous survey; to determine median urinary iodine concentration; to assess level of iodine in salt samples at household and retail shop level; and to ...
Pramod Verma, Banerjee, A, Anupam Banerjee, Chikitsa D Amin, Rajesh K Chudasama, Mahajan, R, Chudasama, RK, Amin, CD, Rajkumar Mahajan, Verma, P   +9 more
core  

Targeted‐Penetrating Biomimetic Hybrid Transfersomes for Enhanced Transdermal Gene Transfection in Hypertrophic Scar Therapy

Advanced Science, EarlyView.
Hypertrophic scar fibroblasts membrane‐hybridized cationic transfersomes enable efficient loading and transdermal delivery of TGF‐β1 siRNA through multiple skin penetration pathways. The biomimetic platform enhances homotypic targeting, transfection, and immune evasion, suppresses TGF‐β1‐driven fibrotic signaling, and reduces extracellular matrix ...
Hui Xing, Ziyi Zhao, Yuhui Yang, Yichen Lin, Yinglin Xuan, Ziyang Wang, Kai Lv, Xiaoxu Zhu, Zhi Zhang, Dong Ma   +9 more
wiley   +1 more source