Future Prospective of Radiopharmaceuticals from Natural Compounds Using Iodine Radioisotopes as Theranostic Agents [PDF]
Natural compounds provide precursors with various pharmacological activities and play an important role in discovering new chemical entities, including radiopharmaceuticals.
Wiwit Nurhidayah+5 more
doaj +7 more sources
Fate of the Iodine Radioisotopes in the Human and Estimation of the Radiation Exposure [PDF]
Fate of the iodine isotopes and resulting organ exposures have been studied using the four-compartment model proposed by BROWNELL to account for the metabolism of this element. Mathematical equations have been established for this model from biological data accepted in the human. They have been used to calculate the amounts of iodine-131 in the thyroid
J. Colard+3 more
semanticscholar +5 more sources
Radioisotopic labeling of human papovavirus (BK) by iodination and reductive alkylation [PDF]
Purified virions of the GS strain of the BK group of human papovaviruses were labeled with 125I using chloramine T or lactoperoxidase or with tritium using sodium borohydride. All viral polypeptides were labeled. Tryptic digests of iodinated VP1 were analyzed.
P.J. Wright, G di Mayorca
openalex +4 more sources
RADIOISOTOPE DIAGNOSTIC ALGORITHM FOR THE RELAPSE AND METASTASES DETECTION IN THE IODINE-NEGATIVE DIFFERENTIATED THYROID CANCER [PDF]
Objective. Developing of algorithm for the post-surgical management of patients with iodine-negative metastases of differentiated thyroid cancer (DTC). Materials and methods. The DTC patients with iodine-negative metastases (n = 115) were enrolled in the study.
O. Solodyannikova+3 more
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Endothelial targeting of polymeric nanoparticles stably labeled with the PET imaging radioisotope iodine-124 [PDF]
Targeting of therapeutics or imaging agents to the endothelium has the potential to improve specificity and effectiveness of treatment for many diseases. One strategy to achieve this goal is the use of nanoparticles (NPs) targeted to the endothelium by ligands of protein determinants present on this tissue, including cell adhesion molecules, peptidases,
Eric Simone+7 more
openalex +4 more sources
Validation of established thyroid ultrasound volume norms in a Chernobyl cohort [PDF]
Objective: To establish thyroid ultrasound volume norms appropriate for studies of diffuse goiter in a cohort of children and adolescents from an iodine-deficient population exposed to 131I by the Chernobyl fallout.
Lydia B Zablotska+12 more
doaj +2 more sources
Nomogram models for predicting outcomes in thyroid cancer patients with distant metastasis receiving 131iodine therapy [PDF]
This study aimed to establish and validate prognostic nomogram models for patients who underwent 131I therapy for thyroid cancer with distant metastases.
Shui Jin+9 more
doaj +2 more sources
Clinical Outcomes of Repeated Radioactive Iodine Therapy for Graves’ Disease [PDF]
Background Radioactive iodine (RAI) therapy is a successful therapeutic modality for Graves’ disease. However, RAI therapy can fail, and RAI therapy after antithyroid drugs (ATDs) has a lower remission rate.
Min Joo Kim+6 more
doaj +1 more source
Most of the radioisotopes that used in medical field, like examination and treatment studies, were produced by employing nuclear reactions. Within the process of a nuclear reaction, one of the most important parameter is the cross–section data which help
Hasan ÖZDOĞAN+2 more
doaj +1 more source
Hyperbaric oxygen therapy as a complementary treatment in neuroblastoma — a narrative review
Neuroblastoma is the most frequently diagnosed cancer during the first year of life. This neoplasm originates from neural crest cells derived from the sympathetic nervous system, adrenal medulla, or paraspinal ganglia.
Diogo Alpuim Costa+14 more
doaj +1 more source