Future Prospective of Radiopharmaceuticals from Natural Compounds Using Iodine Radioisotopes as Theranostic Agents [PDF]
Natural compounds provide precursors with various pharmacological activities and play an important role in discovering new chemical entities, including radiopharmaceuticals.
Wiwit Nurhidayah+5 more
doaj +7 more sources
Fate of the Iodine Radioisotopes in the Human and Estimation of the Radiation Exposure [PDF]
Fate of the iodine isotopes and resulting organ exposures have been studied using the four-compartment model proposed by BROWNELL to account for the metabolism of this element.
J. Colard+3 more
semanticscholar +5 more sources
Radioisotopic labeling of human papovavirus (BK) by iodination and reductive alkylation [PDF]
Purified virions of the GS strain of the BK group of human papovaviruses were labeled with 125I using chloramine T or lactoperoxidase or with tritium using sodium borohydride. All viral polypeptides were labeled. Tryptic digests of iodinated VP1 were analyzed.
P.J. Wright, G di Mayorca
openalex +4 more sources
Features of morfological changes in primary thyroid gland CTLL cultures of rats descendants prenatally exposed by radioisotopes of iodine-131 [PDF]
OBJECTIVE to investigate morphological changes in the primary thyroid cell culture of rat infants whose parents were prenatally exposed by radioisotope iodine 131. MATERIALS AND METHODS obtaining and culturing of thyroid tissue primary cell cultures of
O A Boiko+4 more
openalex +2 more sources
Iodine-131 is increasingly used for diagnostic and therapeutic applications. The excretion of radioactive iodine is primarily through the urine. The safe disposal of radioactive waste is an important component of overall hospital waste management.
Tanate Suksompong+2 more
doaj +2 more sources
RADIOISOTOPE DIAGNOSTIC ALGORITHM FOR THE RELAPSE AND METASTASES DETECTION IN THE IODINE-NEGATIVE DIFFERENTIATED THYROID CANCER [PDF]
Objective. Developing of algorithm for the post-surgical management of patients with iodine-negative metastases of differentiated thyroid cancer (DTC). Materials and methods. The DTC patients with iodine-negative metastases (n = 115) were enrolled in the study.
O. Solodyannikova+3 more
openalex +4 more sources
Endothelial targeting of polymeric nanoparticles stably labeled with the PET imaging radioisotope iodine-124 [PDF]
Targeting of therapeutics or imaging agents to the endothelium has the potential to improve specificity and effectiveness of treatment for many diseases. One strategy to achieve this goal is the use of nanoparticles (NPs) targeted to the endothelium by ligands of protein determinants present on this tissue, including cell adhesion molecules, peptidases,
Eric Simone+7 more
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Repeated KI Prophylaxis in Case of Prolonged Exposure to Iodine Radioisotopes: Pharmacokinetic Studies in Adult Rats [PDF]
To propose a new and effective dose regimen for stable potassium iodide (KI) repeated prophylaxis in case of prolonged exposure to radioactive iodine.The pharmacokinetics of iodine was determined in rats by compartmental analyses after intravenous and oral administrations of the optimal dose of 1 mg/kg KI, which was previously selected in a dose-effect
G. Phan+10 more
semanticscholar +3 more sources
Nomogram models for predicting outcomes in thyroid cancer patients with distant metastasis receiving 131iodine therapy [PDF]
This study aimed to establish and validate prognostic nomogram models for patients who underwent 131I therapy for thyroid cancer with distant metastases.
Shui Jin+9 more
doaj +2 more sources
Clinical Outcomes of Repeated Radioactive Iodine Therapy for Graves’ Disease [PDF]
Background Radioactive iodine (RAI) therapy is a successful therapeutic modality for Graves’ disease. However, RAI therapy can fail, and RAI therapy after antithyroid drugs (ATDs) has a lower remission rate.
Min Joo Kim+6 more
doaj +1 more source