Results 51 to 60 of about 8,718 (206)

Current concepts of 131I therapy in oncology: Indications, methods and follow up [PDF]

Archive of Oncology, 2006
Radioiodine in various forms (as sodium iodide and as the iodinated compounds MIBG, LIPIODOL, et al.) has been used as a therapeutic agent in oncology. Differentiated thyroid carcinoma (DTC) has been successfully treated by 131I therapy.
Mihailović Jasna
doaj   +1 more source

Radioiodination of Two Carborane‐Based Dual Cyclooxygenase‐2/5‐Lipoxygenase Inhibitors and Their In Vitro and In Vivo Evaluation

ChemBioChem, Volume 27, Issue 7, 14 April 2026.
Two dicarbadodecaborane(12)‐based dual cyclooxygenase‐2/5‐lipoxygenase (COX‐2/5‐LO) inhibitors were 123I‐labeled. Refinement of labeling and formulation conditions and extensive in vitro characterization are presented. Cell uptake studies in COX‐2‐ and 5‐LO‐overexpressing cell lines showed COX‐2‐independent and partly 5‐LO‐dependent uptake.
Jonas Schädlich, Martin Ullrich, Cathleen Haase‐Kohn, Robert Wodtke, Sebastian Braun, Maximilian Molitor, Bettina Hofmann, Dieter Steinhilber, Klaus Kopka, Evamarie Hey‐Hawkins, Jens Pietzsch, Markus Laube   +11 more
wiley   +1 more source

Diazirines Beyond Photoaffinity Labeling: A Comprehensive Overview of Applications in Biological Sciences, Materials Chemistry, and NMR‐Spectroscopy

Angewandte Chemie, Volume 138, Issue 4, 22 January 2026.
Diazirines are three‐membered, nitrogen‐containing heterocycles that decompose under light or heat to generate carbenes. For the past two decades, they have served mainly as minimally invasive tags in photoaffinity labeling (PAL). More recently, their value as versatile carbene precursors has been recognized.
Dominik Schnalzer, Viktor Savic, Clemens Cziegler, Michael Schnürch, Marko D. Mihovilovic   +4 more
wiley   +2 more sources

Physico‐Nutritional Profiling and Assessment of Proteins as Well as Soluble and Insoluble Phenolic Acids in Gamma Irradiated Wheat Grains Through SWATH‐MS and HPLC Analysis and Their Functionality

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
Gamma irradiation (Dmin 650 Gy) proved effective in controlling insect pest infestations in stored wheat grains which otherwise undergo extensive losses during storage. SWATH‐MS based proteomics affirmed integrity of major storage proteins including prolamines and increased extractability of phenolics (soluble free & conjugated) was observed in ...
S. Saxena, S. Kumar, D. K. Maurya, J. Tripathi, J. Kumar, A. B. Hadapad, S. Gautam   +6 more
wiley   +1 more source

Iodine dissolution mechanisms in high-pressure aluminoborosilicate glasses and their relationship to oxygen speciation

, 2023
International audienceIncorporation of iodine(I) into high-pressure vitrified glasses appears to be a potential solution for the immobilization of 129I radioisotopes.
Sami Soudani, Jonathan Hamon, Michael Paris, Eric Gautron, Morizet, Yann, Gautron, Eric, Carole La, La, Carole, Soudani, Sami, Paris, Michael, Hamon, Jonathan, Yann Morizet   +11 more
core   +1 more source

Cryosurgery combined with Iodine-125 seed implantation in the treatment of unresectable lung cancer

Chinese Journal of Lung Cancer, 2008
Background and objective As many lung cancer patients lose surgical possibility, it is important to explore new treatments to improve prognosis. The study is to observe adverse reactions and therapeutic effects of cryosurgery combined iodine-125 seeds ...
Hongta ZHOU, Lizhi NIU, Liang ZHOU, Feng MU, Changming ZHANG, Bing LIANG, Daming YANG, Kecheng XU   +7 more
doaj  

Motor and Cognitive Outcome After Subthalamic Nucleus Deep Brain Stimulation in Patients with Parkinson's Disease Harboring GBA1 Variant

Movement Disorders Clinical Practice, Volume 13, Issue 4, Page 973-984, April 2026.
Abstract Background Deep brain stimulation (DBS) is effective for Parkinson's disease (PD); however, its efficacy varies with genetic background, such as the GBA1 variant—the causative gene of Gaucher disease—associated with increased PD risk and cognitive decline after subthalamic nucleus (STN)‐DBS.
Hikaru Kamo, Genko Oyama, Mai Shimizu, Haruka Takeshige‐Amano, Takashi Ogawa, Wataru Sako, Noriko Nishikawa, Taku Hatano, Yuanzhe Li, Hiroyo Yoshino, Manabu Funayama, Masanobu Ito, Hirokazu Iwamuro, Atsushi Umemura, Nobutaka Hattori   +14 more
wiley   +1 more source

Dry and humid heat acclimation induces similar adaptations and cross‐acclimation benefits in trained male cyclists

The Journal of Physiology, Volume 604, Issue 7, Page 2757-2777, 1 April 2026.
Abstract figure legend Adaptive responses to hot‐dry and warm‐humid heat acclimation. Abstract This study compared adaptive responses and cross‐acclimation between dry and humid heat acclimation (HA). In a cross‐over design, trained males completed a heat stress test in hot‐dry (Dry‐HST: 42°C, 25% relative humidity [RH]) and warm‐humid (Humid‐HST: 33°C,
Peter McDonald, Kevin John, Thomas H. Topham, Michael N. Sawka, Brad Clark, Julien D. Périard   +5 more
wiley   +1 more source

A Modified Method for Increasing Radiochemical Purity of I-125 for Radiopharmaceuticals

Atom Indonesia, 2023
Iodine-125 (125I) is one of the radioisotopes widely used in radiopharmaceuticals for diagnosis and therapy of various cancers. Recent reports indicate that there has been shortages in the world supply of this radioiodine isotope.
M Maiyesni, M Mujinah, D. Kurniasih, W Witarti, H Hambali, S. Febriana, I. Kambali   +6 more
doaj   +1 more source

Engineered Elastin‐Like Polypeptides: Intelligent Self‐Assembling Platforms for Biomedical Application

Small Structures, Volume 7, Issue 3, March 2026.
Armed with unique structural and functional properties, elastin‐like polypeptides attract their attentions as programmable materials in biomedical applications, including fusion tags for protein and nucleic acid purification; nanocarriers for protein, chemotherapeutics, and imaging agent delivery; hydrogels for tissue regeneration, 3D model ...
Yang Yuan, Chen Zeng, Zichun Chen, Zhuoga Ciren, Qinran Yu, Chuanbo Wang, Hui Mao, Gang Li, Weizhi Chen, Xiqun Jiang   +9 more
wiley   +1 more source