A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source
Key physicochemical characteristics governing organic micropollutant adsorption and transport in ion-exchange membranes during reverse electrodialysis [PDF]
The co-generation of electricity and electrodialysis of seawater in a hybrid system is a promising approach to overcome water scarcity. Reverse electrodialysis harvests energy from the salinity gradient, where seawater is used as a high salinity stream ...
Cornelissen, Emile +7 more
core +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Assembling all-solid-state batteries presents a unique challenge due to chemical and electrochemical complexities of interfaces between a solid electrolyte and electrodes.
Yi Yang +4 more
doaj +1 more source
ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur +5 more
wiley +1 more source
Ion exchange phase transitions in "doped" water--filled channels
Ion transport through narrow water--filled channels is impeded by a high electrostatic barrier. The latter originates from the large ratio of the dielectric constants of the water and a surrounding media. We show that ``doping'', i.e.
A. Kamenev +8 more
core +1 more source
Harnessing Fungal Biowelding for Constructing Mycelium‐Engineered Materials
Mycelium‐bound composites (MBCs) offer low‐carbon alternatives for construction, yet interfacial bonding remains a critical challenge. This review examines fungal biowelding as a biocompatible adhesive, elucidating mycelium‐mediated interfacial mechanisms and their role in material assembly. Strategies to optimize biowelding are discussed, highlighting
Xue Brenda Bai +2 more
wiley +1 more source
Development of an algorithm for calculating ion exchange processes using the Python ecosystem
Ion exchange plays a key role not only in eliminating water hardness and reducing the concentration of unwanted ions, but also in protecting the environment.
Iryna Chub +5 more
doaj +1 more source
Ion Exchange for Nutrient Recovery Coupled with Biosolids-Derived Biochar Pretreatment to Remove Micropollutants [PDF]
Wastewater, especially anaerobic treatment effluent, contains high ammonia nitrogen (NH4-N) and inorganic orthophosphate (PO4-P), which necessitate additional treatment to meet stringent discharge regulations.
Avila, Anna +4 more
core +1 more source
Packaging of Macroscopic Material Payloads: Needs, Challenges, Concepts, and Future Directions
This review introduces a unified framework that decomposes any macroscopic packaging system into the payload, packaging material, and packaging strategy and combines them into a conceptual packaging equation: packaging strategy = payload + packaging material.
Venkata S. R. Jampani, Manos Anyfantakis
wiley +1 more source

