Results 181 to 190 of about 3,527,182 (275)

Dual‐Functional Membranes With Interfacial MXene/PFSA Nanoarchitectures for Low Hydrogen Permeation in Water Electrolysis and Reduced Vanadium Ion Crossover in Flow Batteries

open access: yesAdvanced Science, EarlyView.
A PFSA/MXene composite membrane is developed for both PEMWE and VRFB applications. MXene incorporation simultaneously enhances proton conductivity and suppresses hydrogen/vanadium crossover. The interaction between MXene functional groups and PFSA's –SO3H reduces the proton diffusion barrier via hydrogen‐bonding networks, while the disordered ...
Panpan Guan   +13 more
wiley   +1 more source

NCLX Inhibition plus Ca2+ Delivery Potentiates Electroporation and Antitumor Immunity in Pancreatic Ductal Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
Electroporation combined with NCLX inhibition and Ca2+ delivery induces mitochondrial Ca2+ overload in PDAC cells, triggering pyroptosis, DAMP release, and antitumor immune activation. Simultaneously, suppression of tumor‐derived SPP1 weakens SPP1–CD44 signaling and remodels macrophages toward an antitumor phenotype, thereby enhancing CD8+ T‐cell ...
Chuanbing Zhao   +7 more
wiley   +1 more source

HADHA K406 Lactylation Regulates Metabolic Reprogramming and Suppresses Immune Responses in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
HADHA K406 lactylation fuels fatty acid β‐oxidation and HMGCR‐dependent cholesterol biosynthesis, fostering immunosuppressive MDSCs and exhausted CD8+ T cells in gastric cancer. Loss of this modification blocks cholesterol production, remodels the tumor microenvironment, and tumor growth is suppressed via combined inhibition of HMGCR and LDHA ...
Maoxiao Feng   +10 more
wiley   +1 more source

Quenching Photo‐Induced Free Radicals Endows Superomniphobic Atmospheric Water Harvesting Hydrogels With UV Resistance for Durable Bifacial Photovoltaic Cooling

open access: yesAdvanced Science, EarlyView.
A hygroscopic hydrogel layer functionalized with fullerene C60 tackles heat and dust challenges in bifacial photovoltaics (PV) panels. It resists soiling and photo‐aging, maintains high transparency, absorbs water vapor from the air during the night, and delivers strong evaporative cooling power during daytime, significantly lowering PV panel ...
Xiaoqi Zhou   +6 more
wiley   +1 more source

Polyphosphate Copper Nanospheres Drive Mitochondrial Metabolic Reprogramming via Calcium Phase Separation for Self‐Sensitizing Cuproptosis

open access: yesAdvanced Science, EarlyView.
This study developed polyphosphate (polyP)‐based nanostructures that enable calcium‐mediated metabolic reprogramming via liquid–liquid phase separation (LLPS). Released polyP undergoes LLPS with Ca2+, suppressing glycolytic flux and enhancing mitochondrial metabolism effectively.
Jing Wang   +10 more
wiley   +1 more source

Comparative Evaluation of Chelator‐Conjugated Peptides for Lead‐Labeled SSTR2‐Targeted Theranostics: Integrated Computational Modeling and Preclinical Validation

open access: yesAdvanced Science, EarlyView.
The study integrates density functional theory with radiochemical and biological validation to compare DOTA‐, PSC‐, and DOTAM‐based chelator‐conjugates for 203Pb/212Pb theranostic applications. Distinct differences in metal coordination, electrostatic properties, conformational flexibility, cellular uptake, biodistribution, and dosimetry are identified
Jeongyun Kim   +12 more
wiley   +1 more source

Hydrodynamic Selection of Polymorphic Assembly Pathways in Plant Protein Amyloid Fibrils

open access: yesAdvanced Science, EarlyView.
Hydrodynamic conditions are revealed to govern polymorphic assembly of soy protein amyloid fibrils. Distinct flow‐induced drafting, kissing, and docking dynamics direct fibril growth into multiple morphologies, linking fluid mechanics with nanoscale assembly and enabling rational design of functional amyloid materials.
Zejian Xu   +8 more
wiley   +1 more source

The Interplay Between Molybdopterin Synthase and Metal Metabolism Contributes to Pathogenicity in Acinetobacter baumannii

open access: yesAdvanced Science, EarlyView.
Pathogenic Acinetobacter baumannii scavenges metal ions as nutritional elements to survive within the host. This study demonstrates that molybdopterin synthase is essential for pathogenesis and full virulence during infection. Molybdopterin synthase subunit MoaE constitutes an intrinsically disordered C‐terminal histidine rich tail, which mediates ...
Min Jiao   +13 more
wiley   +1 more source

Controlling Self‐Doping in Conjugated Polyelectrolyte Copolymers to Vary the Threshold Voltage in OECTs

open access: yesAdvanced Electronic Materials, EarlyView.
Two series of self‐doped conjugated polyelectrolytes are synthesized from a non‐self‐dopable building block 3MEEET and a self‐dopable building‐block 3HOT−[TMA+] or 3HOT−[SO3H] enabling precise control over the degree of self‐doping, which in turn directly governs the threshold voltage (VT) in OECTs over a wide range of 700 mV.
Julian Hungenberg   +7 more
wiley   +1 more source

Deciphering Intricacies in Directional CO2 Conversion From Electrolysis to CO2 Batteries

open access: yesAdvanced Energy Materials, EarlyView.
This review will delve into the inherent connections and distinctions of CO2‐directed conversion in ECO2RR and CO2 batteries, in terms of product types, catalyst selection, catalytic mechanisms, and electrochemical performances, while proposing a benchmarking framework for the evaluation of CO2 batteries and innovative CO2 battery configurations for ...
Changfan Xu   +5 more
wiley   +1 more source

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