Results 251 to 260 of about 536,774 (369)

Offline comprehensive liquid chromatography in combination with a Deoxyribonuclease I immobilized enzymatic reactor for selective screening of oligonucleotide mixtures [PDF]

, 2016
Alvarez Porebski, Piotr Wiktor, Lynen, Frederic   +1 more
core   +1 more source

Ion-Exchange Paper Chromatography [PDF]

Proceedings of the Association of Clinical Biochemists, 1963
openaire   +2 more sources

Insights into Isolation and Purification Strategies of Egg Allergens. [PDF]

Foods
Sibincic N, Prodic I, Apostolovic D, Wai CYY, Leung ASY, Stojadinovic M.   +5 more
europepmc   +1 more source

Ion exchange chromatography and mass spectrometric methods for analysis of cadmium-phytochelatin (II) complexes. [PDF]

Int J Environ Res Public Health, 2013
Rodrigo MA, Cernei N, Kominkova M, Zitka O, Beklova M, Zehnalek J, Kizek R, Adam V.   +7 more
europepmc   +1 more source

Mechanochemical Strategies Applied to the Late‐Stage Modifications of Pharmaceutically Active Compounds

Angewandte Chemie International Edition, Accepted Article.
This review explores the potential of mechanochemistry in the late‐stage modification of active pharmaceutical ingredients (APIs), offering a comprehensive analysis of methods designed to transform structurally complex molecular scaffolds. By examining the scope, efficiency, and mechanistic aspects of these approaches, the review highlights protocols ...
Johanna Templ, Lars Borchardt
wiley   +1 more source

Selective Phosphorylation of Phenols and Benzenediols by the Kinase PsiK and Variants Thereof

Angewandte Chemie International Edition, Accepted Article.
Phosphorylation plays important roles in biology by modulating the structure, reactivity, and biological function of a broad range of molecules. Biocatalytic phosphorylation has attracted attention from synthetic chemists due to its selectivity and mild reaction conditions using ATP as a phosphate donor. Given the potential synthetic utility of kinases
Ahram Kim, Nicolás M. Morato, Prabir Saha, Pascal Eyimegwu, Aqeel A. Niyaz, Rui Huang, R. Graham Cooks, Ryan M. Phelan, Jared C Lewis   +8 more
wiley   +1 more source

A Cobotic, Digitally‐Controlled Schlenk‐line Unlocks Access to Elusive Lewis‐base stabilised Copper Bis(Disilylamides)

Angewandte Chemie International Edition, Accepted Article.
Silylamides are important ligands in coordination chemistry for their ability to stabilize low‐coordination numbers and provide soluble, and even volatile, metal complexes. Such compounds provide valuable insights into the fundamental bonding and reactivity of their respective metals.
Nicola Bell, Marina Gladkikh, Cameron Fraser, Mostafa Elsayed, Emma Richards, Richard Drummond Turnbull   +5 more
wiley   +1 more source

Development of Liquid Chromatography on Monolithic Supports-From First Concepts to Real Analytical and Preparative Techniques. [PDF]

Int J Mol Sci
Friganović T, Josić D.
europepmc   +1 more source

Machine learning‐augmented molecular dynamics simulations (MD) reveal insights into the disconnect between affinity and activation of ZTP riboswitch ligands

Angewandte Chemie International Edition, Accepted Article.
The challenge of targeting RNA with small molecules necessitates a better understanding of RNA‐ligand interaction mechanisms. However, the dynamic nature of nucleic acids, their ligand‐induced stabilization, and how conformational changes influence gene expression pose significant difficulties for experimental investigation.
Christopher Fullenkamp, Shams Mehdi, Christopher Jones, Logan Tenney, Patricio Pichling, Peri R. Prestwood, Adrian R. Ferré-D'Amaré, Pratyush Tiwary, John Schneekloth   +8 more
wiley   +1 more source

An Automated and Precise Approach for the Determination of Azide Residue in Angiotensin II Receptor Blockers Using In Situ Matrix Elimination Ion Chromatography with Switching Strategy. [PDF]

Int J Mol Sci
Lou C, Pan S, Yu X, Zhang K, Zhang K, Zhu Y.   +5 more
europepmc   +1 more source