Results 81 to 90 of about 948,699 (249)
Self-organized enhancement of conductivity in biological ion channels [PDF]
, 2013 We discuss an example of self-organization in a biological system. It arises from long-range ion–ion interactions, and it leads us to propose a new kind of enhanced conduction in ion channels.
Eisenberg, Robert S. +5 more
core +2 more sources
U-shaped bilayer graphene channel transistor with very high Ion/Ioff ratio
, 2011 A novel graphene transistor architecture is reported. The transistor has a U-shaped geometry and was fabricated using a gallium focused ion beam (FIB). The channel conductance was tuned with a back gate.
Boden, Stuart +4 more
core +1 more source
Human Molecular Genetics, 2002 Ion channels serve many functions apart from electrical signal transduction: chemical signalling (Ca(2+) as a second messenger), transepithelial transport, regulation of cytoplasmic or vesicular ion concentration and pH, and regulation of cell volume. Therefore, ion channel dysfunction can cause diseases in many tissues.
Thomas J. Jentsch, Christian A. Hübner
openaire +3 more sources
Fractional diffusion modeling of ion channel gating [PDF]
, 2004 An anomalous diffusion model for ion channel gating is put forward. This scheme is able to describe non-exponential, power-law like distributions of residence time intervals in several types of ion channels.
A. L. Hodgkin +15 more
core +1 more source
TRP Channels in Human Prostate
The Scientific World Journal, 2010 This review gives an overview of morphological and functional characteristics in the human prostate. It will focus on the current knowledge about transient receptor potential (TRP) channels expressed in the human prostate, and their putative role in ...
Carl Van Haute +2 more
doaj +1 more source
Single-channel recordings from cultured human retinal pigment epithelial cells. [PDF]
, 1988 We have applied patch-clamp techniques to on-cell and excised-membrane patches from human retinal pigment epithelial cells in tissue culture. Single-channel currents from at least four ion channel types were observed: three or more potassium-selective ...
Fain, GL, Fox, JA, Pfeffer, BA
core
The Low-Threshold Calcium Channel Cav3.2 Determines Low-Threshold Mechanoreceptor Function
Cell Reports, 2015 The T-type calcium channel Cav3.2 emerges as a key regulator of sensory functions, but its expression pattern within primary afferent neurons and its contribution to modality-specific signaling remain obscure. Here, we elucidate this issue using a unique
Amaury François +12 more
doaj +1 more source
Beam loading in the nonlinear regime of plasma-based acceleration
, 2008 A theory that describes how to load negative charge into a nonlinear, three-dimensional plasma wakefield is presented. In this regime, a laser or an electron beam blows out the plasma electrons and creates a nearly spherical ion channel, which is ...
C. Huang +11 more
core +1 more source
Membrane-Mediated Action of Phosphodiesterase 5 Inhibitors
PharmaceuticsBackground/Objectives: Phosphodiesterase 5 (PDE5) inhibitors, sildenafil, vardenafil, and tadalafil, activate the cyclic guanosine monophosphate pathway resulting in vascular smooth muscle relaxation.
Anna I. Malykhina +2 more
doaj +1 more source
TRPV4 Mediates Acute Bladder Responses to Bacterial Lipopolysaccharides
Frontiers in Immunology, 2020 Urinary tract infections (UTI) affect a large proportion of the population, causing among other symptoms, more frequent and urgent micturition. Previous studies reported that the gram-negative bacterial wall component lipopolysaccharides (LPS) trigger ...
Yeranddy A. Alpizar +19 more
doaj +1 more source