Results 101 to 110 of about 312,868 (268)

In-Silico Investigation of Phyllanthus niruri Phytochemicals as Hepatic Fibrosis Modulators

Biology and Life Sciences Forum
The liver is a pioneer internal organ that orchestrates major metabolic, detoxification, and endocrine roles. Acute factors like hepatitis and drug allergy and chronic causes like metabolic dysfunction-associated fatty liver disease (MASLD) and ...
Chithra Raju, Kavitha Sankaranarayanan
doaj   +1 more source

Low‐Angle Grain Boundaries and Re‐Segregation in Single‐Crystalline Ni‐Base Superalloys

Advanced Engineering Materials, EarlyView.
This work demonstrates that Re‐segregation at low‐angle grain boundaries (LAGBs) in Ni‐base superalloys is influenced by misorientation angle. Advanced microscopy and atom probe tomography reveal that higher misorientation angles increases Re‐segregation.
Alireza B. Parsa, Aparna Saksena, Alesander Kostka, Pascal Thome, Felicitas Scholz, Alexandre Mussi, Christoph Somsen, Baptiste Gault, Jan Frenzel, Gunther Eggeler   +9 more
wiley   +1 more source

Mitochondrial Ion Channels [PDF]

Annual Review of Physiology, 2007
In work spanning more than a century, mitochondria have been recognized for their multifunctional roles in metabolism, energy transduction, ion transport, inheritance, signaling, and cell death. Foremost among these tasks is the continuous production of ATP through oxidative phosphorylation, which requires a large electrochemical driving force for ...
openaire   +2 more sources

Field Report from Collaborative Research Center 1625: Heterogeneous Research Data Management Using Ontology Representations

Advanced Engineering Materials, EarlyView.
A unified research data management framework for heterogeneous materials data is presented. The system integrates multimodal datasets using ontologies and knowledge graphs, enabling interoperability and FAIR (findable, accessible, interoperable, reusable) data principles. By linking data across scales and workflows, it supports reproducible, Artifitial
Doaa Mohamed, Samuel García Vázquez, Behnam Mardani, Victor Dudarev, Alfred Ludwig, Maribel Acosta, Markus Stricker   +6 more
wiley   +1 more source

The sodium-leak channel, NALCN, in health and disease

Frontiers in Cellular Neuroscience, 2014
Ion channels are crucial components of cellular excitability and are involved in many neurological diseases. This review focuses on the sodium leak, G protein-coupled receptors (GPCRs)-activated NALCN channel that is predominantly expressed in neurons ...
Maud eCochet-Bissuel, Maud eCochet-Bissuel, Maud eCochet-Bissuel, Maud eCochet-Bissuel, Philippe eLory, Philippe eLory, Philippe eLory, Philippe eLory, Arnaud eMonteil, Arnaud eMonteil, Arnaud eMonteil, Arnaud eMonteil   +11 more
doaj   +1 more source

Towards Defect Phase Diagrams: From Research Data Management to Automated Workflows

Advanced Engineering Materials, EarlyView.
A research data management infrastructure is presented for the systematic integration of heterogeneous experimental and simulation data required for defect phase diagrams. The approach combines openBIS with a companion application for large‐object storage, automated metadata extraction, provenance tracking and federated data access, thereby supporting ...
Khalil Rejiba, Sang‐Hyeok Lee, Christina Gasper, Martina Freund, Sandra Korte‐Kerzel, Ulrich Kerzel   +5 more
wiley   +1 more source

Time‐Dependent Oxidation and Scale Evolution of a Wrought Co/Ni‐Based Superalloy

Advanced Engineering Materials, EarlyView.
This study shows how a new wrought Co/Ni‐based superalloy resists oxidation at 800 ∘$^\circ$C. The oxide scale changes from rough, fast‐growing spinel to a dense, protective chromia–alumina layer. Atom probe analysis reveals tiny refractory‐rich bubbles at the interface that mark the transition to long‐term, diffusion‐controlled protection ...
Cameron Crabb, Zachary T. Kloenne, Samuel R. Rogers, Chi Hang Dominik Kwok, Mark C. Hardy, Michele S. Conroy, David Dye   +6 more
wiley   +1 more source

Karl Popper and the Mechanisms of Hydrogen Embrittlement

Advanced Engineering Materials, EarlyView.
Representation of the beginning of loss of ductility rather than embrittlement. Small concentrations of hydrogen in a diffusible form within iron are well‐established to harm the mechanical integrity of steels. There are theories that attempt to explain the pernicious role of hydrogen.
H. K. D. H. Bhadeshia
wiley   +1 more source

The odyssey of the TR(i)P journey to the cellular membrane

Frontiers in Cell and Developmental Biology
Ion channels are integral membrane proteins mediating ion flow in response to changes in their environment. Among the different types of ion channels reported to date, the super-family of TRP channels stands out since its members have been linked to many
Bastián Rivera, Bastián Rivera, Octavio Orellana-Serradell, Octavio Orellana-Serradell, Evrim Servili, Evrim Servili, Evrim Servili, Rodrigo Santos, Rodrigo Santos, Sebastián Brauchi, Sebastián Brauchi, Oscar Cerda, Oscar Cerda   +12 more
doaj   +1 more source

[Mitochondrial ion channels].

Postepy biochemii, 2006
Ion channels are proteins, which facilitate the ions flow throught biological membranes. In recent years the structure as well as the function of the plasma membrane ion channels have been well investigated. The knowledge of intracellular ion channels however is still poor.
Skalska, Jolanta, Debska-Vielhaber, Grazyna, Głab, Marta, Kulawiak, Bogusz, Malińska, Dominika, Koszela-Piotrowska, Izabela, Piotr Bednarczyk, Krzysztof Dołowy, Adam Szewczyk   +8 more
openaire   +1 more source