Results 1 to 10 of about 630,739 (251)
DNA-nanostructure-templated assembly of planar and curved lipid-bilayer membranes
Lipid-bilayer nanodiscs and liposomes have been developed to stabilize membrane proteins in order to study their structures and functions. Nanodiscs are detergent-free, water-soluble, and size-controlled planar phospholipid-bilayer platforms.
Mostafa A. Elbahnasawy, Mahmoud L. Nasr
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PDMS as a Substrate for Lipid Bilayers
PDMS (polydimethylsiloxane) is a cheap, optically clear polymer that is elastic and can be easily and quickly fabricated into a wide array of microscale and nanoscale architectures, making it a versatile substrate for biophysical experiments on cell membranes.
James A. Goodchild +3 more
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Computational Investigation of the Effect of Lipid Membranes on Ion Permeation in Gramicidin A
Membrane proteins are embedded in a lipid bilayer and interact with the lipid molecules in subtle ways. This can be studied experimentally by examining the effect of different lipid bilayers on the function of membrane proteins.
Jeffry Setiadi, Serdar Kuyucak
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Antibiotic Loaded Phytosomes as a Way to Develop Innovative Lipid Formulations of Polyene Macrolides
Background: The threat of antibiotic resistance of fungal pathogens and the high toxicity of the most effective drugs, polyene macrolides, force us to look for new ways to develop innovative antifungal formulations.
Svetlana S. Efimova, Olga S. Ostroumova
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Dielectric Properties of Phosphatidylcholine Membranes and the Effect of Sugars
Simple carbohydrates are associated with the enhanced risk of cardiovascular disease and adverse changes in lipoproteins in the organism. Conversely, sugars are known to exert a stabilizing effect on biological membranes, and this effect is widely ...
Victoria Vitkova +6 more
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Effects of carotenoids on lipid bilayers
Carotenoids have been found to be important in improving the integrity of biomembranes in eukaryotes.
Quentin R. Johnson +4 more
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One of the hallmarks of Alzheimer's disease is the formation of senile plaques, primarily consisting of amyloid-β (Aβ) peptides. Peptide-membrane and peptide-lipid interactions are thought to be crucial in this process.
Hannah Dies +2 more
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Aggregation of Aß(25-35) on DOPC and DOPC/DHA bilayers: an atomic force microscopy study.
β amyloid peptide plays an important role in both the manifestation and progression of Alzheimer disease. It has a tendency to aggregate, forming low-molecular weight soluble oligomers, higher-molecular weight protofibrillar oligomers and insoluble ...
Matilde Sublimi Saponetti +7 more
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Energy transfer in lipid bilayers
The quenching of fluorescence due to energy transfer between a dilute, random array of donor and acceptor chromophores in lipid bilayer was measured and compared to theoretical expressions developed to predict the decrease in emission intensity under these circumstances. The observed intensity was found to be the same function of quencher concentration
Estep, T.N., Thompson, T.E.
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FLUCTUATIONS IN LIPID BILAYERS: ARE THEY UNDERSTOOD? [PDF]
We review recent computer simulation studies of undulating lipid bilayers. Theoretical interpretations of such fluctuating membranes are most commonly based on generalized Helfrich-type elastic models, with additional contributions of local "protrusions" and/or density fluctuations. Such models provide an excellent basis for describing the fluctuations
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