Results 1 to 10 of about 112,656 (211)
Fluctuations, inherent in flexible and biologically relevant lipid bilayers, make quantitative structure determination challenging. Shortcomings in older methods of structure determination have been realized and new methodologies have been introduced that take fluctuations into account.
J F, Nagle, S, Tristram-Nagle
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Glycophorin in Lipid Bilayers [PDF]
Glycophorin, the major glycoprotein of human erythrocytes, has been isolated and reincorporated into lipid vesicles. Freeze-fracture electron microscopy shows the reincorporated glycophorin to occur as small particles in vesicle fracture faces while the etch faces are smooth.
C W, Grant, H M, McConnell
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Structure of lipid bilayers [PDF]
The quantitative experimental uncertainty in the structure of fully hydrated, biologically relevant, fluid (L(alpha)) phase lipid bilayers has been too large to provide a firm base for applications or for comparison with simulations. Many structural methods are reviewed including modern liquid crystallography of lipid bilayers that deals with the fully
J F, Nagle, S, Tristram-Nagle
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Volumetric stability of lipid bilayers [PDF]
In agreement with recent reports, a commercial densimeter has yielded a gradual decrease in lipid molecular volume of DPPC multilamellar vesicle dispersions in the gel phase upon repeated thermal cycling between 10 °C and 50 °C. The considerable size of this decrease would have significant implications for the physical chemistry of biomembranes.
Hallinen, Kelsey M. +2 more
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Alcohol Interactions with Lipid Bilayers [PDF]
We investigate the structural changes to lipid membrane that ensue from the addition of aliphatic alcohols with various alkyl tail lengths. Small angle neutron diffraction from flat lipid bilayers that are hydrated through water vapor has been employed to eliminate possible artefacts of the membrane curvature and the alcohol’s membrane-water ...
Kondela, T. +5 more
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Composition Fluctuations in Lipid Bilayers [PDF]
Abstract Lipid bilayers constitute the basis of biological membranes. Understanding lipid mixing and phase behavior can provide important insights into membrane lateral organization (the “raft” hypothesis). Here we investigate model lipid bilayers below and above their miscibility transition temperatures.
Baoukina, Svetlana +2 more
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DNA-encircled lipid bilayers [PDF]
We describe a method to harness the programmability of DNA nanotechnology to create DNA-encircled lipid bilayers.
Katarina Iric +9 more
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Cholesterol's location in lipid bilayers [PDF]
It is well known that cholesterol modifies the physical properties of lipid bilayers. For example, the much studied liquid-ordered Lo phase contains rapidly diffusing lipids with their acyl chains in the all trans configuration, similar to gel phase bilayers. Moreover, the Lo phase is commonly associated with cholesterol-enriched lipid rafts, which are
Drew, Marquardt +4 more
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Electrostatics of lipid bilayer bending
The electrostatic contribution to spontaneous membrane curvature is calculated within Poisson-Boltzmann theory under a variety of assumptions and emphasizing parameters in the physiological range. Asymmetric surface charges, either fixed with respect to bilayer midplane area, or with respect to the lipid-water area both induce curvature but of opposite
Chou, T., Jarić, M.V., Siggia, E.D.
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Functional tethered lipid bilayers
Our strategy to provide the structural basis for the build-up of functional tethered membranes focuses on three approaches: the first one is based on the pre-organization of a monomolecular layer of a lipopolymer at the water/air interface which is then transferred to a solid support.
Knoll, W. +8 more
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