Results 11 to 20 of about 779,547 (295)
A quantitative analysis of ligand binding at the protein-lipid bilayer interface [PDF]
Communications ChemistryThe majority of drugs target membrane proteins, and many of these proteins contain ligand binding sites embedded within the lipid bilayer. However, targeting these therapeutically relevant sites is hindered by limited characterization of both the sites ...
Allison Pearl Barkdull +2 more
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Functional regulation of aquaporin dynamics by lipid bilayer composition [PDF]
Nature CommunicationsWith the diversity of lipid-protein interactions, any observed membrane protein dynamics or functions directly depend on the lipid bilayer selection.
Anh T. P. Nguyen +2 more
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Patterning artificial lipid bilayer on nanostructured surfaces
International Journal of Nanomedicine, 2018 Ranjita Ghosh Moulick,1 Gregor Panaitov,2 Sung-Eun Choi,2 Dirk Mayer,2 Andreas Offenhäusser2 1School of Physical Science, Jawaharlal Nehru University, New Delhi, India; 2Bioelectronics, ICS8/PGI8, Forschungszentrum Juelich, Juelich, Germany ...
Ghosh Moulick R +4 more
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Biophysica, 2023 The interaction of many peptides with lipid bilayer membranes strongly depends on the lipid composition. Here, a study of the impact of unsaturated lipid acyl chains on the interaction of a derivative of the HIV-1 fusion peptide with lipid bilayer ...
William T. Heller, Piotr A. Zolnierczuk
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Water Pores in Planar Lipid Bilayers at Fast and Slow Rise of Transmembrane Voltage
Membranes, 2021 Basic understanding of the barrier properties of biological membranes can be obtained by studying model systems, such as planar lipid bilayers. Here, we study water pores in planar lipid bilayers in the presence of transmembrane voltage.
Alenka Maček Lebar +3 more
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Biophysica, 2023 Understanding the membrane interactions of the N-terminal 17 residues of the huntingtin protein (HttN) is essential for unraveling its role in cellular processes and its impact on huntingtin misfolding. In this study, we used atomic force microscopy (AFM)
Yasith Indigahawela Gamage, Jianjun Pan
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Current Opinion in Structural Biology, 2000 Fluctuations, inherent in flexible and biologically relevant lipid bilayers, make quantitative structure determination challenging. Shortcomings in older methods of structure determination have been realized and new methodologies have been introduced that take fluctuations into account.
J F, Nagle, S, Tristram-Nagle
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Glycophorin in Lipid Bilayers [PDF]
Proceedings of the National Academy of Sciences, 1974 Glycophorin, the major glycoprotein of human erythrocytes, has been isolated and reincorporated into lipid vesicles. Freeze-fracture electron microscopy shows the reincorporated glycophorin to occur as small particles in vesicle fracture faces while the etch faces are smooth.
C W, Grant, H M, McConnell
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DNA-nanostructure-templated assembly of planar and curved lipid-bilayer membranes
Frontiers in Chemistry, 2023 Lipid-bilayer nanodiscs and liposomes have been developed to stabilize membrane proteins in order to study their structures and functions. Nanodiscs are detergent-free, water-soluble, and size-controlled planar phospholipid-bilayer platforms.
Mostafa A. Elbahnasawy, Mahmoud L. Nasr
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Structure of lipid bilayers [PDF]
Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes, 2000 The quantitative experimental uncertainty in the structure of fully hydrated, biologically relevant, fluid (L(alpha)) phase lipid bilayers has been too large to provide a firm base for applications or for comparison with simulations. Many structural methods are reviewed including modern liquid crystallography of lipid bilayers that deals with the fully
J F, Nagle, S, Tristram-Nagle
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