Results 41 to 50 of about 216,390 (293)

Correlated diffusion in lipid bilayers [PDF]

Proceedings of the National Academy of Sciences, 2021
SignificanceDynamic processes on membrane surfaces are essential for biological function. Traditionally, quantitative measurements of lipid/protein motion have been interpreted in the framework of membrane hydrodynamics. However, some recent single-molecule tracking studies have proven difficult to interpret via hydrodynamic arguments.
Rafael L. Schoch, Frank L. H. Brown, Gilad Haran   +2 more
openaire   +2 more sources

BLM Analyzer: a software tool for experiments on planar lipid bilayers

BioTechniques, 2007
Planar lipid bilayers represent a versatile platform for studying the functions of various membrane proteins as well as the development of biosensors.
Pavel Novák, Marta Gaburjáková, Ivan Zahradník   +2 more
doaj   +1 more source

Cell-free protein expression systems in microdroplets: stabilization of interdroplet bilayers

, 2013
Cell-free protein expression with bacterial lysates has been demonstrated to produce soluble proteins in microdroplets. However, droplet assays with expressed membrane proteins require the presence of a lipid bilayer.
Hywel Morgan, Mark S. Friddin, Maurits R. R. de Planque, Patnaik R.   +3 more
core   +1 more source

Insight from Molecular dynamic simulation of reactive oxygen species in oxidized skin membrane

Scientific Reports, 2018
Non-enzymatic lipid peroxidation of the skin-lipid bilayer causes perturbations that affect the biomembrane structure, function, and permeability of reactive oxygen species (ROS).
Surendra Kumar, Dharmendra Kumar Yadav, Eun-Ha Choi, Mi-Hyun Kim   +3 more
doaj   +1 more source

Main phase transition in lipid bilayers: phase coexistence and line tension in a soft, solvent-free, coarse-grained model

, 2010
We devise a soft, solvent-free, coarse-grained model for lipid bilayer membranes. The non-bonded interactions take the form of a weighted-density functional which allows us to describe the thermodynamics of self-assembly and packing effects of the coarse-
Allen M. P., Helfrich W., Israelachvili J. N., Lodish H., Marcus Müller, Martin Hömberg, Mouritsen O. G., Safran S. A., van Konynenburg P. H., Warren P.   +9 more
core   +1 more source

Hydrophobic silver nanoparticles trapped in lipid bilayers: Size distribution, bilayer phase behavior, and optical properties

Journal of Nanobiotechnology, 2008
Background Lipid-based dispersion of nanoparticles provides a biologically inspired route to designing therapeutic agents and a means of reducing nanoparticle toxicity.
Bothun Geoffrey D
doaj   +1 more source

Membrane docking geometry of GRP1 PH domain bound to a target lipid bilayer: an EPR site-directed spin-labeling and relaxation study. [PDF]

PLoS ONE, 2012
The second messenger lipid PIP(3) (phosphatidylinositol-3,4,5-trisphosphate) is generated by the lipid kinase PI3K (phosphoinositide-3-kinase) in the inner leaflet of the plasma membrane, where it regulates a broad array of cell processes by recruiting ...
Huai-Chun Chen, Brian P Ziemba, Kyle E Landgraf, John A Corbin, Joseph J Falke   +4 more
doaj   +1 more source

Characterization of the transverse relaxation rates in lipid bilayers [PDF]

, 1990
The 2H NMR transverse relaxation rates of a deuterated phospholipid bilayer reflect slow motions in the bilayer membrane. A study of dimyristoyl lecithin specifically deuterated at several positions of the hydrocarbon chains indicates that these motions ...
Chan, Sunney I., Dea, Phoebe, Watnick, Paula I.   +2 more
core  

Native silica nanoparticles are powerful membrane disruptors [PDF]

, 2015
Silica nanoparticles are under development for intracellular drug delivery applications but can also have cytotoxic effects including cell membrane damage.
Alkhammash, Hend I., Berthier, Rémy, de Planque, Maurits R.R., Li, Nan   +3 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source