Results 31 to 40 of about 140,194 (304)

Interactions of Novel Phosphonium Dye with Lipid Bilayers: A Molecular Dynamics Study

open access: yesEast European Journal of Physics, 2022
In the present work the 100-ns molecular dynamics simulations (MD) were performed in the CHARMM36m force field using the GROMACS package to estimate the bilayer location and mechanisms of the interaction between the novel phosphonium dye TDV and the ...
Olga Zhytniakivska
doaj   +1 more source

Controlled delivery of membrane proteins to artificial lipid bilayers by nystatin-ergosterol modulated vesicle fusion [PDF]

open access: yes, 2006
The study of ion channels and other membrane proteins and their potential use as biosensors and drug screening targets require their reconstitution in an artificial membrane.
Fisher, K.H.   +22 more
core   +1 more source

Geometrical and electrophysiological data of the moving membrane method for the osmotic water permeability of a lipid bilayer

open access: yesData in Brief, 2021
Data of the osmotic water permeability of a lipid bilayer (diphytanoylphosphaticylcholin) in the presence of cholesterol (30 mole%) are shown under the simultaneous measurement of bilayer tension.
Keita Yano   +3 more
doaj   +1 more source

Impedance analysis and single ion channel recordings on pore-suspending lipid bilayers based on highly ordered pore arrays [PDF]

open access: yes, 2006
Ion channels are one of the main drug targets and are in the focus of various membrane biosensor applications and drug screening assays. The aim of this thesis was to develop and characterize a novel membrane system suspending highly ordered porous ...
Römer, Winfried
core   +1 more source

Physical and Chemical Interplay Between the Membrane and a Prototypical Potassium Channel Reconstituted on a Lipid Bilayer Platform

open access: yesFrontiers in Molecular Neuroscience, 2021
Once membrane potential changes or ligand binding activates the ion channel, the activity of the channel is finely modulated by the fluctuating membrane environment, involving local lipid composition and membrane tension.
Masayuki Iwamoto, Shigetoshi Oiki
doaj   +1 more source

Neural Stem Cell Spreading on Lipid Based Artificial Cell Surfaces, Characterized by Combined X-ray and Neutron Reflectometry [PDF]

open access: yes, 2010
We developed a bioadhesive coating based on a synthetic peptide-conjugate (AK-cycloRGDfC]) which contains multiples of the arginyl-glycyl-aspartic acid (RGD) amino acid sequence.
Gabor Mezo   +19 more
core   +1 more source

Quantitative Estimation of Cyclotide-Induced Bilayer Membrane Disruption by Lipid Extraction with Mesoscopic Simulation [PDF]

open access: yes, 2021
Cyclotide-induced membrane disruption is studied at the microsecond timescale by Dissipative Particle Dynamics (DPD) to quantitatively estimate a kinetic rate constant for membrane lipid extraction with a “sandwich” interaction model where two bilayer ...
Karina, van den Broek   +4 more
core   +1 more source

Multiscale compression-induced restructuring of stacked lipid bilayers: From buckling delamination to molecular packing.

open access: yesPLoS ONE, 2022
Lipid membranes in nature adapt and reconfigure to changes in composition, temperature, humidity, and mechanics. For instance, the oscillating mechanical forces on lung cells and alveoli influence membrane synthesis and structure during breathing ...
Marilyn Porras-Gómez   +7 more
doaj   +2 more sources

Interaction of the Antimicrobial Peptide Aurein 1.2 and Charged Lipid Bilayer

open access: yesScientific Reports, 2017
Aurein 1.2 is a potent antimicrobial peptide secreted by frog Litoria aurea. As a short membrane-active peptide with only 13 amino acids in sequence, it has been found to be residing on the surface of lipid bilayer and permeabilizing bacterial membranes ...
Durgesh K. Rai, Shuo Qian
doaj   +1 more source

Physical Properties and Reactivity of Microdomains in Phosphatidylinositol-Containing Supported Lipid Bilayer

open access: yesMembranes, 2021
We characterized the size, distribution, and fluidity of microdomains in a lipid bilayer containing phosphatidylinositol (PI) and revealed their roles during the two-dimensional assembly of a membrane deformation protein (FBP17).
Toshinori Motegi   +4 more
doaj   +1 more source

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