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Pharmacological characterization of TMEM16A currents [PDF]
Channels, 2014 Recent studies have shown that transmembrane protein 16 A (TMEM16A) is a subunit of calcium-activated chloride channels (CACCs). Pharmacological agents have been used to probe the functional role of CACCs, however their effect on TMEM16A currents has not been systematically investigated.
Gérard sergeant +2 more
exaly +3 more sources
Recent progress in structural studies on TMEM16A channel
Computational and Structural Biotechnology Journal, 2020 The calcium-activated chloride channel, also known as TMEM16A, shows both calcium and membrane potential dependent activation. The channel is expressed broadly and contributes to a variety of physiological processes, and it is expected to be a target for the treatment of diseases such as hypertension, pain, cystic fibrosis and lung cancer.
Yafei Chen, Hailong An, Sai Shi
exaly +4 more sources
Some of the next articles are maybe not open access.
Recent advances in TMEM16A: Structure, function, and disease
Journal of Cellular Physiology, 2019Xuzhao Wang, Yafei Chen, Hailong An
exaly
Activation of TMEM16A by natural product canthaxanthin promotes gastrointestinal contraction
FASEB Journal, 2020Yafei Chen, Hailong An, Sai Shi
exaly
Anoctamin-1/TMEM16A is the major apical iodide channel of the thyrocyte
American Journal of Physiology - Cell Physiology, 2014R Beauwens, V Kruys, J Van Sande
exaly
Chloride ion transport and overexpression of TMEM16A in a guinea‐pig asthma model
Clinical and Experimental Allergy, 2017Mitsuko Kondo
exaly
Development of the Olfactory Epithelium and Nasal Glands in TMEM16A-/- and TMEM16A+/+ Mice. [PDF]
PLoS ONE, 2015 TMEM16A/ANO1 is a calcium-activated chloride channel expressed in several types of epithelia and involved in various physiological processes, including proliferation and development.
Devendra Kumar Maurya +7 more
doaj +8 more sources