Results 141 to 150 of about 46,486 (306)

What have we learned from two-pore potassium channels? Their molecular configuration and function in the human heart

, 2012
Two-pore domain potassium channels (K2P) control excitability, stabilize the resting membrane potential below firing threshold, and accelerate repolarisation in different cells.
Szalontai, B., Ötvös, Ferenc, Benyhe, S., Boyett, M., Vágvölgyi, Csaba, Szûts, V., Papp, J.G., Dobrzynski, H.; id_orcid, Szüts, Viktória, Dézsi, László, Szalontai, Balázs, Dobrzynski, Halina, Zhang, Henggui, Benyhe, Sándor, Dézsi, L., Varró, András, Boyett, Marc, Vágvölgyi, C., Varró, A., Ötvös, F., Zhang, H., Papp, Gyula, Erdélyi, L., Erdélyi, Lajos   +23 more
core  

Monolithic 3D‐Integrated All‐Solid Ion‐Gated Carbon Nanotube Transistors With Tunable Ionic Conductance for Multi‐Timescale Reservoir Computing

Advanced Materials, EarlyView.
A dual‐timescale reservoir based on monolithically 3D (M3D)‐integrated CNT solid ion‐gated transistors is demonstrated. Tunable ionic dynamics and pulse‐engineered operation enable linear and symmetric synaptic updates. The M3D‐integrated array achieves robust temporal encoding and accurate classification of moving MNIST sequences, highlighting its ...
Haksoon Jung, Hanbin Cho, Yongwoo Lee, Seunghun Baek, Hyeongjun Kim, Yun Goo Ro, Hyunhyub Ko, Joonki Suh, Yong‐Young Noh, Jimin Kwon   +9 more
wiley   +1 more source

Conductive Hydrogels for Exogenous Sensing and Cell Fate Control

Advanced Materials, EarlyView.
We engineer electrically conductive hydrogels by combining sulfated glycosaminoglycans with semiconducting polymers. These hydrogels bind bioactive proteins, including growth factors, whose release or retention can be modulated by low‐voltage stimulation. The hydrogels are also integrated as 3D channels in organic electrochemical transistors as part of
Teuku Fawzul Akbar, Carlos Alejandro Jimenez‐Rodriguez, Railia Biktimirova, Ilka Hermes, Thomas Kurth, My Duyen Pham, Mikhail Tsurkan, Jens Friedrichs, Francis L. C. Morgan, Hans Kleemann, Olga Guskova, Uwe Freudenberg, Peter Fratzl, Carsten Werner, Christoph Tondera, Ivan R. Minev   +15 more
wiley   +1 more source

Openings of the rat recombinant alpha1 homomeric glycine receptor as a function of the number of sgonist molecules bound

, 2002
The functional properties of rat homomeric {alpha}1 glycine receptors were investigated using whole-cell and outside-out recording from human embryonic kidney cells transfected with rat {alpha}1 subunit cDNA.
Beato, M., Colquhoun, D., Groot-Kormelink, P.J., Sivilotti, L.G.   +3 more
core  

Weaving Intelligence: Thermally Drawn Multimaterial Fibers Toward AI‐Enabled Smart Textiles

Advanced Materials, EarlyView.
Thermally drawn multimaterial fibers are rapidly advancing as intelligent structural units for next‐generation smart textiles. Integrating multimaterial architectures with neuromorphic and spiking‐neural‐network principles enables fabrics that can sense, compute, and adapt autonomously.
Vuong Dinh Trung, Jiaxiang Yi, Hieu Nguyen‐Duc, Tien Nu Hoang Lo, Weili Zhao, Chaoqun Dong, Fabien Sorin, Baris Caglar, Lei Wei, Tung Nguyen‐Dang   +9 more
wiley   +1 more source

Spring-like mechanics enable rapid inactivation and stochastic single-channel gating of the mechanically activated PIEZO channel

Cell Reports
Summary: PIEZO ion channels generate force-induced macroscopic currents that rapidly inactivate but display repetitive single-channel opening and closing under steady membrane tension.
Wenhao Liu, Xiaochun Zhang, Qijing He, Yang Meng, Boxue Tian, Bailong Xiao   +5 more
doaj   +1 more source

Second‐Harmonic Hyper‐Mie Optical Activity Enables Closed‐Loop Chiral Photochemistry

Advanced Materials, EarlyView.
Nonlinear chiral photochemistry is demonstrated in CdTe/CdO nanohelices, where circularly polarized infrared light both drives and tracks photo‐oxidation via second‐harmonic scattering. This closed‐loop process reveals real‐time structural evolution, including shell fracturing and core exposure, accompanied by a transition from hyper‐Mie to hyper ...
Hoyeon Choi, Kody Whisnant, Ben J. Olohan, E. Petronijevic, G. Dan Pantoș, Nicholas A. Kotov, Ventsislav K. Valev   +6 more
wiley   +1 more source

Water, Protons, and the Gating of Voltage-Gated Potassium Channels

Membranes
Ion channels are ubiquitous throughout all forms of life. Potassium channels are even found in viruses. Every cell must communicate with its surroundings, so all cells have them, and excitable cells, in particular, especially nerve cells, depend on the ...
Alisher M. Kariev, Michael E. Green
doaj   +1 more source

Designable van der Waals Crystal for Artificial Neuronal Cell Mimicking

Advanced Materials, EarlyView.
Designable van der Waals crystal has been demonstrated for device‐scale neuronal cell mimicking. The structural similarity between ion‐channel in biological membranes and layered vdW lattices is realized with nano‐crystallization via Ar + H2S plasma sulfurization.
Jinhyoung Lee, Gunhyoung Kim, Dongho Lee, Seowoo Son, Hyunho Seok, Sihoon Son, Hyunbin Choi, Geonwook Kim, Geumji Back, Hyunkyu Kim, Chaerin Park, Junmin Ahn, Seongyun Je, Chaeyoung Im, Junil Cho, Magdalena Grzeszczyk, Seongho Kim, Eunseo Go, Hyunwoo Shim, Donghwan Choi, Muyoung Kim, Hyoeng‐U. Kim, Won‐Jun Jang, Taesung Kim   +23 more
wiley   +1 more source

Membrane mechanics as a probe of ion-channel gating mechanisms [PDF]

, 2008
The details of conformational changes undergone by transmembrane ion channels in response to stimuli, such as electric fields and membrane tension, remain controversial.
Sens, Pierre, Phillips, Rob, Reeves, Daniel, Ursell, Tristan, Kondev, Jane   +4 more
core