Results 51 to 60 of about 1,568,609 (304)
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Negative ion sources of neutral beam injection (NBI) systems for future fusion devices like ITER (“The Way” in Latin) rely on the surface conversion of hydrogen (or deuterium) atoms and positive ions to negative ions in an inductively coupled plasma (ICP)
Sofia Cristofaro +2 more
doaj +1 more source
By reevaluating a 13-month stretch of Ulysses SWICS H pickup ion measurements near 5 AU close to the ecliptic right after the previous solar minimum, this paper presents a determination of the neutral interstellar H density at the solar wind termination ...
Auchère +82 more
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Kinetic Scale Density Fluctuations in the Solar Wind
We motivate the importance of studying kinetic scale turbulence for understanding the macroscopic properties of the heliosphere, such as the heating of the solar wind.
Bale, S. D. +5 more
core +1 more source
Tin-graphene tubes as anodes for lithium-ion batteries with high volumetric and gravimetric energy densities. [PDF]
Limited by the size of microelectronics, as well as the space of electrical vehicles, there are tremendous demands for lithium-ion batteries with high volumetric energy densities.
Kong, Dejia +12 more
core
Confined H$$^-$$ ion within a density functional framework
25 pages, 6 figures, 8 ...
Majumdar, Sangita +2 more
openaire +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Rapid density fluctuations in the solar wind [PDF]
Electron density fluctuations (up to 2.5 Hz) in the solar wind have been studied, using the EFW experiment on the Cluster spacecraft, which measures density through measurements of the biased probe potentials relative to the spacecraft.
P. J. Kellogg, T. S. Horbury
doaj +1 more source
Modulational instability of ion-acoustic wave packets in quantum pair-ion plasmas
Amplitude modulation of quantum ion-acoustic waves (QIAWs) in a quantum electron-pair-ion plasma is studied. It is shown that the quantum coupling parameter $H$ (being the ratio of the plasmonic energy density to the Fermi energy) is ultimate responsible
A. Hasegawa +18 more
core +1 more source

