Results 111 to 120 of about 454,051 (310)

Research Status and Application Prospects of LiMnPO_4 as A New Generation Cathode Material for Lithium-Ion Batteries

, 2015
Olivine-structured lithium manganese phosphate (LiMnPO_4) has the following advantages: excellent thermal stability, low cost, high safety and environmental benignity.
Hu Huasheng, Xia Yonggao, Xiao Feng, Liu Zhaoping, Chen Lipeng, Qin Laifen   +5 more
core  

4th Generation ECR Ion Sources [PDF]

, 2008
The concepts and technical challenges related to developing a 4th generation ECR ion source with an RF frequency greater than 40 GHz and magnetic confinement fields greater than twice Becr will be explored in this paper.
Todd, D.S., Prestemon, S., Lyneis, Claude M., Sabbi, G., Ferracin, P., Leitner, D., Caspi, S.   +6 more
core  

Ion rarefaction waves and associated phenomena

, 1982
This thesis contains an experimental and theoretical study of the response of a plasma to the motion of the positive space-charge sheath which bounds it.
Coates, Andrew J., Coates, A
core   +1 more source

Research on Negative Helium Ion Beam Generation Technology

Yuanzineng kexue jishu
Tandem accelerator can generate MeV-level positive ion beam, of which He ion beam can be used for experimental research and industrial applications such as ion beam analysis and ion implantation, which is an indispensable ion beam for tandem accelerator.
CHEN Haonan1, 2, CUI Baoqun1, 2, TANG Bing1, 2, CHEN Lihua1, 2, MA Ruigang1, 2, MA Yingjun1, 2, MA Xie1, 2, ZHANG Yifan1, 2, ZHAO Jiange1, 2, WANG Yunfeng1, 2, YANG Chao1, 2, YU Rongkai1, 2
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Effects of D-region RF heating studied with the Sodankyla ion chemistry model [PDF]

, 2005
International audienceThe upper mesosphere and lower thermosphere, or ionospheric D region, is an atmospheric layer which is difficult to access experimentally.
A. Seppälä, A. Senior, Turunen, T., Ulich, T., Seppälä, A., C.-F. Enell, Enell, C.-F., Honary, F., P. T. Verronen, Marple, S., S. Marple, A. Kero, E. Turunen, Senior, A., Ulich, Th., Turunen, E., Th. Ulich, F. Honary, Verronen, P. T., Kero, A.   +19 more
core   +1 more source

VL51ES (Generation 6) Li-Ion Cell for Satellites

E3S Web of Conferences, 2017
This paper presents the design of Saft’s VL51ES (Generation 6) Li-Ion cell, the main challenges in the course of the development, the main BOL characteristics and performances achieved during the development program.
Defer M., Borthomieu Y., Ligneel E., Badet S., Chocinski D.   +4 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source