Results 101 to 110 of about 454,051 (310)

A new type of Na+-driven ATP synthase membrane rotor with a two-carboxylate ion-coupling motif [PDF]

, 2013
: The anaerobic bacterium Fusobacterium nucleatum uses glutamate decarboxylation to generate a transmembrane gradient of Na+. Here, we demonstrate that this ion-motive force is directly coupled to ATP synthesis, via an F1Fo-ATP synthase with a novel Na ...
Leone, V, Yildiz, Ö, Meier, T, Iglesias-Cans, M, Cook, G., Sarah Schulz (426341), Meier, Thomas, Sarah Schulz, Matthies, D., Meier, T. ; https://orcid.org/, Schulz, Sarah, Özkan Yildiz (244574), M. Cook, Gregory, Doreen Matthies (426343), Thomas Meier, José D. Faraldo-Gómez (426344), Faraldo-Gómez, J., José D Faraldo-Gómez, Yildiz, Ö. ; https://orcid.org/, Iglesias-Cans, Marina, Gregory M. Cook (255231), Krah, A, Alexander Krah, https://orcid.org/, Vanessa Leone, Cook, Gregory M., Yildiz, Özkan, Meier, Thomas Kurt, Alexander Krah (217992), Cook, GM, Iglesias-Cans, M., Schulz, S, Doreen Matthies, Schulz, S., Leone, Vanessa, Matthies, D, Leone, V., Marina Iglesias-Cans, Marina Iglesias-Cans (426342), Thomas Meier (244580), Gregory M Cook, Krah, Alexander, Matthies, Doreen, Faraldo-Gómez, José D., Faraldo-Gómez, JD, Vanessa Leone (266195), Ozkan Yildiz, Krah, A.   +47 more
core   +1 more source

Tris(pentafluorophenyl)borane-Catalyzed Carbenium Ion Generation and Autocatalytic Pyrazole Synthesis-A Computational and Experimental Study. [PDF]

Angew Chem Int Ed Engl, 2021
Dasgupta A, Babaahmadi R, Pahar S, Stefkova K, Gierlichs L, Yates BF, Ariafard A, Melen RL.   +7 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Electric potential and ion drag force in highly collisional complex plasma [PDF]

, 2008
This PhD thesis is a cumulative dissertation that consists of three papers. The first paper describes the qualitative as well as quantitative nature of the electrostatic potential behind a macroparticle in a drifting collisional plasma and also the ion
Chaudhuri, M., Chaudhuri, Manis
core  

Probing the relationship between electromagnetic ion cyclotron waves and plasmaspheric plumes near geosynchronous orbit [PDF]

, 2010
Plasmaspheric plumes created during disturbed geomagnetic conditions have been suggested as a major cause of increased occurrences of electromagnetic ion cyclotron (EMIC) waves at these times.
R. B. Horne, M. J. Engebretson, M. R. Lessard, Denton, M.H., Horne, R.B., Posch, J.L., Murphy, M.T., Engebretson, M.J., M. T. Murphy, J. L. Posch, Lessard, M.R., M. H. Denton   +11 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Generation of Fast Ions by Microclusters

Plasma and Fusion Research, 2010
Laser-irradiated microclusters can generate energetic ions that produce fusion reactions. The amount and spectrum of these ions depend on the cluster-size distribution, electron heating mechanism, and cluster expansion dynamics. This paper describes recent physics results pertinent to the items listed.
AREFIEV, Alexey, BREIZMAN, Boris, KHUDIK, Vladimir, GAO, Xiaohui, DOWNER, Michael   +4 more
openaire   +2 more sources

Single atom gas field ion sources for scanning ion microscopy

, 2016
This chapter discusses fabrication and experimental evaluation of W(111) single atom tips (SATs) for gas field ion source applications. Firstly, a brief history of field ion microscopy (FIM) will be given since it will be heavily relied on throughout the
Pitters, Jason L., Urban, Radovan, Radovan Urban, Robert A. Wolkow, Jason L. Pitters, Wolkow, Robert A.   +5 more
core   +1 more source

Ion-Specific Interactions at a Mineral-Water Interface Revealed by Surface-Sensitive Spectroscopy under Flow Conditions

, 2023
A solid surface in contact with an aqueous solution is typically charged. When put in contact with an aqueous electrolyte solution, the surface charge and composition are crucially affected by the composition of the aqueous phase due to ion-specific ...
Patrick Ober, Sophia H. Kolbinger, Patrick Ober (8452926), Mischa Bonn, Ellen H. G. Backus (7430489), Mischa Bonn (1235496), Sophia H. Kolbinger (16485170), Ellen H. G. Backus   +7 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source