Results 81 to 90 of about 7,700,334 (333)
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Advanced Electrode Materials in Lithium Batteries: Retrospect and Prospect
Lithium- (Li-) ion batteries have revolutionized our daily life towards wireless and clean style, and the demand for batteries with higher energy density and better safety is highly required.
Xin Shen +10 more
doaj +1 more source
Generation of focusing ion beams by magnetized electron sheath acceleration. [PDF]
We present the first 3D fully kinetic simulations of laser driven sheath-based ion acceleration with a kilotesla-level applied magnetic field. The application of a strong magnetic field significantly and beneficially alters sheath based ion acceleration ...
Arefiev, AV +4 more
core +1 more source
Concept for controlled transverse emittance transfer within a linac ion beam [PDF]
For injection of beams into circular machines with different horizontal and vertical emittance acceptance, the injection efficiency can be increased if these beams are flat, i.e. if they feature unequal transverse emittances.
D. Edwards +4 more
core +3 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Ultrahigh harmonics from laser-assisted ion-atom collisions
We present a theoretical analysis of high-order harmonic generation from ion-atom collisions in the presence of linearly polarized intense laser pulses.
A. McPherson +4 more
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Development of the RF Ion Sources for Focused Ion Beam Accelerators [PDF]
The paper presents the results of investigations of ion sources developed in the IAP of NAS of Ukraine for generation of high brightness ion beams with small energy spread.
V. Voznyi +5 more
doaj
Dissipation-Assisted Quantum Information Processing with Trapped Ions
We introduce a scheme to perform dissipation-assisted quantum information processing in ion traps considering realistic decoherence rates, for example, due to motional heating. By means of continuous sympathetic cooling, we overcome the trap heating, and
Bermudez, A., Plenio, M. B., Schaetz, T.
core +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source

