Results 81 to 90 of about 454,051 (310)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Battery choice and management for New Generation Electric Vehicles [PDF]
, 2005 Different types of electric vehicles (EVs) have been recently designed with the aim of solving pollution problems caused by the emission of gasoline-powered engines.
Affanni, A. +22 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Investigation of a miniature differential ion thruster
, 2011 Complex space missions involving formation flying or drag compensation are driving the need for spacecraft propulsion systems capable of providing low but also highly accurate thrust levels.
Collingwood, C., Collingwood, Cheryl
core
Efficient carbon ion beam generation from laser-driven volume acceleration
New Journal of Physics, 2013 Experimental data on laser-driven carbon C ^6+ ion acceleration with a peak intensity of 5 × 10 ^20 W cm ^−2 are presented and compared for opaque target normal sheath acceleration (TNSA) and relativistically transparent laser–plasma interactions ...
D Jung +16 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
The Astrophysical Journal LettersThe ion-scale electromagnetic waves are observed frequently within 0.3 au. Their generation and dissipation driven by wave–particle interaction are very important energy transfer processes in the weak collision corona and solar wind and may be one of the
Wen Liu, Huan-Yu Jia, Si-Ming Liu
doaj +1 more source
A Review of Aerosol Nanoparticle Formation from Ions
KONA Powder and Particle Journal, 2014 Ion-induced nucleation (IIN) mechanism has been widely accepted as an efficient source of new particle formation in the middle and upper troposphere. However, there have been debates on its contribution to the nucleation events observed in the boundary ...
Qing Li, Jingkun Jiang, Jiming Hao
doaj +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source