Results 31 to 40 of about 4,111,539 (306)

ICRF heating schemes for the HL-2M tokamak

open access: yesNuclear Fusion, 2023
The HL-2M tokamak is a new medium-sized tokamak at SouthWestern Institute of Physics. Two of its key missions are to achieve 10 keV ion temperature and investigate the behavior of energetic particles relevant to burning plasmas.
L.F. Lu   +11 more
doaj   +1 more source

Generation and direct observation of a triplet arylnitrenium ion

open access: yesNature Communications, 2022
Nitrenium ions are highly electrophilic reactive intermediates of formula R−N−R+, nitrogen analogue of carbenes. Here the authors report the detection of a triplet nitrenium ion using time-resolved spectroscopic methods and ab initio computations ...
Lili Du   +7 more
doaj   +1 more source

An analysis of pump-induced artificial ionospheric ion upwelling at EISCAT [PDF]

open access: yes, 2010
Ion outflow from the high-latitude ionosphere is a well-known phenomenon and an important source of plasma for the magnetosphere. It is also well known that pumping the ionosphere with high-power high-frequency radio waves causes electron heating.
Kosch, M.J.   +4 more
core   +4 more sources

The modulation of ion channels in cancer chemo-resistance

open access: yesFrontiers in Oncology, 2022
Ion channels modulate the flow of ions into and out of a cell or intracellular organelle, leading to generation of electrical or chemical signals and regulating ion homeostasis.
Jiayu Zhao, Mei Li, Jiao Xu, Wei Cheng
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Generation R

open access: yes, 2022
Generation R onderzoekt de groei, ontwikkeling en gezondheid van 10.000 opgroeiende kinderen in Rotterdam (prospective cohort study). Deze kinderen worden al gevolgd vanaf de vroege zwangerschap en blijven we volgen tot hun jong volwassenheid.
Erasmus MC, afdeling Generation R
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Pathways to Next‐Generation Fire‐Safe Alkali‐Ion Batteries

open access: yesAdvanced Science, 2023
High energy and power density alkali‐ion (i.e., Li+, Na+, and K+) batteries (AIBs), especially lithium‐ion batteries (LIBs), are being ubiquitously used for both large‐ and small‐scale energy storage, and powering electric vehicles and electronics ...
Yubai Zhang   +8 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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