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How do plants maintain pH and ion homeostasis under saline-alkali stress? [PDF]
Frontiers in Plant Science, 2023 Salt and alkaline stresses often occur together, severely threatening plant growth and crop yields. Salt stress induces osmotic stress, ionic stress, and secondary stresses, such as oxidative stress.
Jing Li, Yongqing Yang
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Adaptive metabolic rewiring and ion homeostasis enhance oxidative stress resistance in Lacticaseibacillus casei [PDF]
Applied and Environmental MicrobiologyEnhancing the oxidative stress tolerance of microorganisms is critical for maintaining their viability and functionality in industrial fermentation under aerobic conditions.
Lei Su +6 more
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Nanoenabled Intracellular Metal Ion Homeostasis Regulation for Tumor Therapy [PDF]
Advanced ScienceEndogenous essential metal ions play an important role in many life processes, especially in tumor development and immune response. The approval of various metallodrugs for tumor therapy brings more attention to the antitumor effect of metal ions.
Lihua Xu +8 more
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Ultrasound-actuated ion homeostasis perturbator for oxidative damage-augmented Ca2+ interference therapy and combined immunotherapy [PDF]
Materials Today BioCalcium ion therapy has shown promise for cancer treatment, but its efficacy is limited by the cellular calcium buffering mechanism. Herein, an ion homeostasis disruptor (PCCa) was synthesized using an in situ mineralization method.
Mi Yang +6 more
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Identification and analysis of prognostic ion homeostasis characteristics in kidney renal clear cell carcinoma [PDF]
HeliyonKidney renal clear cell carcinoma (KIRC), a prevalent primary malignant tumor within the urinary system, is characterized by significant heterogeneity. It has been shown that ion channels are important targets for anti-tumor therapy.
Xiangmin Zhang +5 more
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Frontiers in Cellular Neuroscience, 2023 How do neurons that implement cell-autonomous self-regulation of calcium react to knockout of individual ion-channel conductances? To address this question, we used a heterogeneous population of 78 conductance-based models of hippocampal pyramidal ...
Sunandha Srikanth +2 more
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A new vesicle trafficking regulator CTL1 plays a crucial role in ion homeostasis. [PDF]
PLoS Biology, 2017 Ion homeostasis is essential for plant growth and environmental adaptation, and maintaining ion homeostasis requires the precise regulation of various ion transporters, as well as correct root patterning.
Yi-Qun Gao +8 more
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Estropause, Sex Hormones and Metal Homeostasis in the Mouse Brain
Frontiers in Neurology, 2022 Alterations in brain metal ion homeostasis have been reported with aging and are implicated in the pathogenesis of neurodegenerative diseases. To assess whether age-related changes in hypothalamic-pituitary-gonadal (HPG) hormones might be involved in ...
Tianbing Liu +8 more
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Aggregate, 2023 Intracellular zinc ion (Zn2+) accumulation disrupts the Zn2+ homeostasis, providing an ion‐overloading anticancer strategy with great potential. The self‐adaptation of tumor cells to ion concentration, however, puts forward higher requirements for the ...
Yuping Jiang +6 more
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Materials & Design, 2021 Chemotherapy is one of the most used method for cancer therapy, however, brings huge pain to patients as the drugs commonly causes side effects. Inducing tumor cells apoptosis by perturbing ion homeostasis is a novel approach to replace chemotherapy in ...
Long Pang +6 more
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