Lactoferrin. A natural glycoprotein involved in iron and inflammatory homeostasis [PDF]
, 2017 Human lactoferrin (hLf), an iron-binding multifunctional cationic glycoprotein secreted by exocrine glands and by neutrophils, is a key element of host defenses.
Cutone, Antimo +4 more
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Live-Cell Imaging of Physiologically Relevant Metal Ions Using Genetically Encoded FRET-Based Probes
Cells, 2019 Essential biochemical reactions and processes within living organisms are coupled to subcellular fluctuations of metal ions. Disturbances in cellular metal ion homeostasis are frequently associated with pathological alterations, including neurotoxicity ...
Helmut Bischof +7 more
doaj +1 more source
Ion activities and potassium uptake mechanisms of glial cells in guinea-pig olfactory cortex slices. [PDF]
, 1987 1. Double-barrelled ion-sensitive micro-electrodes were used to measure changes in the intracellular activities of K+, Na+ and Cl- (aiK, aiNa, aiCl) in glial cells of slices from guinea-pig olfactory cortex during repetitive stimulation of the lateral ...
Ballanyi, Klaus +2 more
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Cell Reports, 2020 Summary: Amyotrophic lateral sclerosis (ALS) manifests pathological changes in motor neurons and various other cell types. Compared to motor neurons, the contribution of the other cell types to the ALS phenotypes is understudied. G4C2 repeat expansion in
Shuangxi Li +9 more
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Neurodegeneration Upon Dysfunction of Endosomal/Lysosomal CLC Chloride Transporters
Frontiers in Cell and Developmental Biology, 2021 The regulation of luminal ion concentrations is critical for the function of, and transport between intracellular organelles. The importance of the acidic pH in the compartments of the endosomal-lysosomal pathway has been well-known for decades.
Shroddha Bose +4 more
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STOCHASTIC DYNAMICS OF CELL LINEAGE IN TISSUE HOMEOSTASIS. [PDF]
, 2019 During epithelium tissue maintenance, lineages of cells differentiate and proliferate in a coordinated way to provide the desirable size and spatial organization of different types of cells.
Chen, Weitao, Nie, Qing, Qiu, Yuchi
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An investigation of acute effects at various doses of malathion on glucose homeostasis and insulin resistance in rat liver, pancreas and serum [PDF]
, 2020 Objective. This study investigates acute effects of various doses of Malathion on glucose homeostasis and insulin resistance in rat. Methods. Rats were randomly divided into four groups of 6 animals each. Corn oil was given orally to Group 1.
Ekremoğlu, Murat +4 more
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Promising Antifungal Targets Against Candida albicans Based on Ion Homeostasis
Frontiers in Cellular and Infection Microbiology, 2018 In recent decades, invasive fungal infections have been increasing significantly, contributing to high incidences and mortality in immunosuppressed patients. Candida albicans (C.
Yiman Li +5 more
doaj +1 more source
Bistable dynamics underlying excitability of ion homeostasis in neuron models
, 2014 When neurons fire action potentials, dissipation of free energy is usually not directly considered, because the change in free energy is often negligible compared to the immense reservoir stored in neural transmembrane ion gradients and the long-term ...
Dahlem, Markus A. +2 more
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Targeting ion homeostasis in metabolic diseases: Molecular mechanisms and targeted therapies
Pharmacological ResearchThe incidence of metabolic diseases—hypertension, diabetes, obesity, metabolic dysfunction-associated steatotic liver disease (MASLD), and atherosclerosis—is increasing annually, imposing a significant burden on both human health and the social economy ...
Yanjiao Zhang +6 more
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