Results 91 to 100 of about 30,983 (257)

Differential neuroproteomic and systems biology analysis of spinal cord injury [PDF]

, 2016
Acute spinal cord injury (SCI) is a devastating condition with many consequences and no known effective treatment. Although it is quite easy to diagnose traumatic SCI, the assessment of injury severity and projection of disease progression or recovery ...
Bramlett, Helen M, Das, Jyotirmoy H, Dietrich, W. Dalton, Moghieb, Ahmed, Selig, Tyler, Wang, Kevin K. W, Wang, Michael S, Yang, Zhihui, Yost, Richard A   +8 more
core   +2 more sources

Photoconductivity‐Driven Quantum Efficiency Gain in Inorganic Ruddlesden‐Popper Layered Cs2PbBr2I2 Perovskite Photodetector for Visible Light Detection

Advanced Functional Materials, EarlyView.
Rational halogen mixing strategy was employed to shift the bandgap of Cs2PbBr2I2 from ultraviolet to visible region, enabling first realization of a visible‐light photodetector with this 2D layered Ruddlesden‐Popper perovskite material. Under illumination, light‐induced internal field forms and drives trap‐mediated persistent photoconductivity ...
Md Fahim Al Fattah, Asif Abdullah Khan, Saikiran Khamgaonkar, Majid Haji Bagheri, Danyah Khan, Md Rasidul Islam, Mahmoud Almadoun, Aixi Pan, Alexander Li, Marwa Abd‐Ellah, Vivek Maheshwari, Dayan Ban   +11 more
wiley   +1 more source

The use of Ion Mobility Mass Spectrometry to probe Modulation of Function of p53 and of MDM2 by Small Molecule Inhibitors

Frontiers in Molecular Biosciences, 2015
Developing drug-like molecules to inhibit the interactions formed by disordered proteins is sought after but challenging due in part to the lack of solved structures from conformationally dynamic systems.
Eleanor Rose Dickinson, Ewa eJurneczko, Judith eNicholson, Ted eHupp, Joanna eZawacka-Pankau, Galina eSelivanova, Perdita Elizabeth Barran   +6 more
doaj   +1 more source

Applications of Mass Spectrometry in the Onset of Amyloid Fibril Formation: Focus on the Analysis of Early-Stage Oligomers

Frontiers in Chemistry, 2020
Amyloid fibril formation is a hallmark of diverse neurodegenerative and metabolic diseases, such as Alzheimer's disease (AD), Parkinson's disease (PD), and type 2 diabetes mellitus (T2DM).
Jiaojiao Hu, Qiuling Zheng
doaj   +1 more source

Incorporating standardised drift-tube ion mobility to enhance non-targeted assessment of the wine metabolome (LC×IM-MS) [PDF]

, 2017
Liquid chromatography with drift-tube ion mobility spectrometry-mass spectrometry (LCxIM-MS) is emerging as a powerful addition to existing LC-MS workflows for addressing a diverse range of metabolomics-related questions [1,2].
Causon, Tim, Petrusheva, Dragana, Bogeva, Elena, Ivanova, Violeta, Hann, Stephan   +4 more
core  

Structural Characterization of Anticancer Drug Paclitaxel and Its Metabolites Using Ion Mobility Mass Spectrometry and Tandem Mass Spectrometry [PDF]

, 2018
Paclitaxel (PTX) is a popular anticancer drug used in the treatment of various types of cancers. PTX is metabolized in the human liver by cytochrome P450 to two structural isomers, 3'-p-hydroxypaclitaxel (3p-OHP) and 6 alpha-hydroxypaclitaxel (6 ...
Cho, Y, Hong, A, Kim, HI, Kim, S, Kim, WJ, Lee, HH   +5 more
core   +1 more source

Broadband, Flexible, Skin‐Compatible Carbon Dots/Graphene Photodetectors for Wearable Applications

Advanced Functional Materials, EarlyView.
Broadband, flexible photodetectors integrating nitrogen‐rich carbon dots with single‐layer graphene on plastic substrates are demonstrated. A biocompatible chitosan–glycerol electrolyte enables efficient low‐voltage gating and on‐skin operation. The devices exhibit ultraviolet‐to‐near‐infrared response, mechanical robustness under bending, and verified
Nouha Loudhaief, Petr Rozhin, Ilaria Bertuol, Ali Raza, Leonardo Viti, Subhankar Roy, Enrico Cavarzerani, Luca Sbuelz, Matteo Brilli, Andrea Serinolli, Jacopo Nicoletti, Riccardo Piccoli, Sebastián Castilla, Simone Dal Zilio, Enrique Rodríguez‐Castellón, Miriam Serena Vitiello, Maurizio Selva, Flavio Rizzolio, Alvise Perosa, Giovanni Antonio Salvatore, Domenico De Fazio   +20 more
wiley   +1 more source

Collision-induced dissociation of doubly-charged barium-cationized lipids generated from liquid samples by atmospheric pressure matrix-assisted laser desorption/ionization provides structurally diagnostic product ions [PDF]

, 2017
Obtaining structural information for lipids such as phosphatidylcholines, in particular the location of double bonds in their fatty acid constituents, is an ongoing challenge for mass spectrometry (MS) analysis.
Cramer, Rainer, Hale, Oliver J.
core   +1 more source

Lithium Intercalation in the Anisotropic Van Der Waals Semiconductor CrSBr

Advanced Functional Materials, EarlyView.
We report the lithium intercalation in the layered van der Waals crystal CrSBr, revealing strongly anisotropic ion‐migration dynamics. Optical and electrical characterization of exfoliated CrSBr shows lithium diffusion coefficients that differ by more than an order of magnitude along a‐ and b‐directions, consistent with molecular dynamics simulations ...
Kseniia Mosina, Aljoscha Söll, Jiří Šturala, Martin Veselý, Petr Levinsky, Ondřej Kaman, Florian Dirnberger, Giuliana Materzanini, Nicola Marzari, Gian‐Marco Rignanese, Borna Radatović, Vlastimil Mazánek, David Sedmidubský, Zdeněk Sofer   +13 more
wiley   +1 more source

Innovative direct introduction‐ion mobility–mass spectrometry (DI‐IM‐MS) approach for fast and robust isomer‐specific quantification in a complex matrix: Application to 2′‐fucosyllactose (2’‐FL) in breast milk

Journal of Mass Spectrometry
AbstractIdentification and specific quantification of isomers in a complex biological matrix by mass spectrometry alone is not an easy task due to their identical chemical formula and therefore their same mass‐to‐charge ratio (m/z). Here, the potential of direct introduction combined with ion mobility–mass spectrometry (DI‐IM‐MS) for rapid ...
Rathahao-Paris, Estelle, Abdoun, Sarah, Paris, Alain, Guillon, Blanche, Venot, Eric, Fenaille, François, Adel-Patient, Karine, Alves, Sandra   +7 more
openaire   +4 more sources