Results 181 to 190 of about 30,983 (257)

Self-Assembly, Rearrangement, and Disassembly of {Cr₆} Horseshoe Oligomers. [PDF]

Angew Chem Int Ed Engl
Geue N, Kumar D, Ham J, Huang S, Timco GA, Burton NA, Winpenny REP, Anggara K, Barran PE.   +8 more
europepmc   +1 more source

Mass Spectrometry Imaging‐Assisted Discovery of Gallotannin Biosynthetic Genes in the Root of Paeonia suffruticosa

Advanced Science, EarlyView.
An integrated approach combining mass spectrometry imaging, transcriptomics, and phylogenetic analysis facilitated the efficient identification of genes involved in gallotannin biosynthesis in Paeonia suffruticosa. As a result, a key UGT and several SCPL acyltransferases responsible for biosynthesizing pentagalloylglucose were successfully identified ...
Yushi Liu, Wenna Duan, Weiwei Tang, Yucheng Zhao, Bin Li   +4 more
wiley   +1 more source

Effects of Hydration on Transthyretin Conformational Dynamics and Oligomerization. [PDF]

Biochemistry
Hampton J, Lantz C, Rider RL, Yun SD, Laganowsky A, Russell DH.   +5 more
europepmc   +1 more source

TEAD1 Enhances Exosome Secretion and Promotes Exosome‐Mediated Tissue Regeneration

Advanced Science, EarlyView.
TEAD1 functions as a crucial molecular switch regulating exosome secretion in various cell types. TEAD1 enhances exosome secretion by upregulating key proteins associated with exosome secretion, including RAB11, CD9, and SNAP23. This study reveals a novel role for TEAD1 in regulating exosome secretion and tissue regeneration, particularly in diabetic ...
Yan Pu, Yi Wan, Wenhao Shi, Bin Li, Haiyue Zhang, Jun Wu, Lingling Li, Wenjia Guo, Chen Ding, Wenjun Yang   +9 more
wiley   +1 more source

Enhancing Lipidomics With High-Resolution Ion Mobility-Mass Spectrometry. [PDF]

Proteomics
Lu G, Xu S, Huang P, Li L.
europepmc   +1 more source

KDM4A Erases the H3R17me2a Mark, Facilitating Chromosome Condensation

Advanced Science, EarlyView.
This study reveals a reversible histone modification switch governing chromosome condensation during mitosis. PKCα‐activated KDM4A removes H3R17me2a, permitting Suv39h1‐driven H3K9me3 deposition. This epigenetic transition recruits the chromosomal passenger complex and triggers Aurora B‐dependent H3S10 phosphorylation, coordinating chromatin remodeling
Yena Cho, Jee Won Hwang, Gyu Hwan Hyun, Sangkyu Lee, Dae‐Geun Song, Su‐Nam Kim, Yong Kee Kim   +6 more
wiley   +1 more source

Stabilizing Proteins by Chemical Cross-Linking: Insights into Conformation, Unfolding, and Aggregation Using Native Ion Mobility Mass Spectrometry. [PDF]

Anal Chem
Sadighi R, van Paasen RMA, Hutchins GH, Jansen ID, Neubacher S, Grossmann TN, Rijs AM.   +6 more
europepmc   +1 more source

In Situ Lipoprotein‐seeking Dye for in Vivo Real‐Time Imaging of Lipid Dysregulation Diseases

Advanced Science, EarlyView.
This study develops lipoprotein‐seeking NIR‐II dyes that specifically bind circulating lipoproteins. These dyes form ultra‐stable complexes with endogenous lipoprotein, enabling real‐time, high‐contrast imaging of fatty liver and atherosclerotic plaques. Tunable binding kinetics allow customized imaging windows.
Yijing Du, Zetao Dang, Baofeng Xu, Jiajun Xu, Dan Wang, Yuewei Zhang, Shoujun Zhu   +6 more
wiley   +1 more source

Rapid Annotation Strategy for <i>in Vivo</i> Phase II Metabolites of Anabolic-Androgenic Steroids Using Liquid Chromatography-Ion Mobility-Mass Spectrometry. [PDF]

J Am Soc Mass Spectrom
Koomen DC, Leaptrot KL, May JC, Rose BS, Lira KE, Raziel JA, Pumford AD, de A Cavalcanti G, Padilha MC, Pereira HMG, McLean JA.   +10 more
europepmc   +1 more source

The Role of Ionic Liquids at the Biological Interfaces in Bioelectronics

Advanced Science, EarlyView.
Ionic liquids (ILs) are highlighted as key artificial ionic materials that bridge biological ion‐based signaling and electronic devices. By understanding their composition, structure, function relationships, and mechanisms, ILs can advance from high performance electrolyte to core materials enabling integrated, multifunctional bioelectronics for ...
Yeong‐sinn Ye, Young Jin Jo, Ji Yeon Oh, Ju Yeon Jeong, Lili Guo, Tae‐il Kim   +5 more
wiley   +1 more source