Structural Evidence for the Tetrameric Assembly of Chemokine CCL11 and the Glycosaminoglycan Arixtra™ [PDF]
Biomolecules, 2013 Understanding chemokine interactions with glycosaminoglycans (GAG) is critical as these interactions have been linked to a number of inflammatory medical conditions, such as arthritis and asthma.
Julie A. Leary +2 more
doaj +4 more sources
Recent Advances in Small Molecule Metabolites Analysis by Ion Mobility-Mass Spectrometry [PDF]
Zhipu Xuebao, 2022 Recently, different types of ion mobility techniques have sprung up. Combined with mass spectrometry, the utility of ion mobility spectrometry has been enhanced in metabolomics, natural products, characterization of supramolecular materials, and other ...
LIU Juan1,2 +4 more
doaj +1 more source
Ion Mobility-Mass Spectrometry and Their Application in Nanocluster Characterization [PDF]
Zhipu Xuebao, 2022 Nano-clusters based materials have received increasing attention as smart materials owing to their unique optical, electronic properties, which make their promising for a wide range of applications, such as catalysis, sensors, and drug delivery, which ...
WANG Wei-guo1,2 +6 more
doaj +1 more source
Application of Native Ion MobilityMass Spectrometry in the Study of Protein Structure and Conformational Diseases [PDF]
Zhipu Xuebao, 2022 Native mass spectrometry (MS) enables the maintenance of intramolecular and intermolecular noncovalent interactions in the gas phase, thus can be used for characterization of proteins and protein complexes under the near “native” conditions. Ion mobility
ZHUANG Xiao-yu;BIAN Xin-yu;LIU Shu;LIU Zhi-qiang;SONG Feng-rui
doaj +1 more source
Metabolic profiling of human blood by high-resolution ion mobility mass spectrometry (IM-MS) [PDF]
International Journal of Mass Spectrometry, 2010 A high resolution ion mobility time-of-flight mass spectrometer with electrospray ionization source (ESI-IM-MS) was evaluated as an analytical method for rapid analysis of complex biological samples such as human blood metabolome was investigated.
Prabha, Dwivedi +2 more
openaire +2 more sources
Molecules, 2022 Plantago asiatica L. (PAL) as a medicinal and edible plant is rich in chemical compounds, which makes the systematic and comprehensive characterization of its components challenging.
Hongxue Gao +5 more
doaj +1 more source
Collision Cross Section Prediction Based on Machine Learning
Molecules, 2023 Ion mobility-mass spectrometry (IM-MS) is a powerful separation technique providing an additional dimension of separation to support the enhanced separation and characterization of complex components from the tissue metabolome and medicinal herbs.
Xiaohang Li +8 more
doaj +1 more source
Cryogenic ion mobility-mass spectrometry for the study of conformations of host-guest complexes
EPJ Techniques and Instrumentation, 2023 Variable-temperature cryogenic ion mobility-mass spectrometry (VT-Cryo-IM-MS) was developed to examine the conformations of host-guest complexes. The VT-Cryo-IM-MS consists of an electrospray ionization source, a quadrupole ion trap, a cryogenic ion ...
Keijiro Ohshimo +5 more
doaj +1 more source
Online Hydrogen-Deuterium Exchange Traveling Wave Ion Mobility Mass Spectrometry (HDX-IM-MS): a Systematic Evaluation [PDF]
Journal of the American Society for Mass Spectrometry, 2017 Hydrogen-deuterium exchange mass spectrometry (HDX-MS) is an important tool for measuring and monitoring protein structure. A bottom-up approach to HDX-MS provides peptide level deuterium uptake values and a more refined localization of deuterium incorporation compared with global HDX-MS measurements.
Cryar, Adam +2 more
openaire +2 more sources
Ion Mobility-Mass Spectrometry-Based Measurements of Collision Cross Section Values for Metabolites and Related Databases [PDF]
Zhipu Xuebao, 2022 Metabolomics aims to systematically profile various small molecules (i.e., metabolites and lipids) in biological samples. Compared with genomics, transcriptomics and proteomics, metabolomics locates in the downstream of omics technologies, which links ...
CHEN Xi1,2 +2 more
doaj +1 more source