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Tandem ion mobility-mass spectrometry (IMS-MS) study of ion evaporation from ionic liquid-acetonitrile nanodrops

Physical Chemistry Chemical Physics, 2009
Ion evaporation is an essential step in the formation of charged ions from electrosprays, yet many aspects of the process are poorly understood. The ion evaporation kinetics of the 1-ethyl-3-methyl-imidazolium+ (EMI+) based ionic liquids (ILs) EMI-BF4, EMI-bis(perfluoroethylsulfonyl)imide, EMI-bis(trifluoromethylsulfonyl)imide and EMI-tris ...
Christopher J, Hogan   +1 more
openaire   +2 more sources

Use of ion-mobility mass spectrometry (IMS-MS) to map polyoxometalate Keplerate clusters and their supramolecular assemblies

Chemical Communications, 2013
We present the high-resolution (HRES-MS) and ion-mobility (IMS-MS) mass spectrometry studies of icosahedral nanoscale polyoxometalate-based {L(30)}{(Mo)Mo(5)} Keplerate clusters, and demonstrate the use of IMS-MS to resolve and map intact nanoclusters, and its potential for the discovery of new structures, in this case the first gas phase observation ...
Philip J, Robbins   +4 more
openaire   +2 more sources

Ion Mobility-Mass Spectrometry (IM-MS) for Top-Down Proteomics: Increased Dynamic Range Affords Increased Sequence Coverage

Analytical Chemistry, 2012
A general approach that combines mass spectrometry (MS), collision-induced dissociation (CID), ion mobility (IM), and MS for top-down proteomics is described, denoted as MS-CID-IM-MS. Using this approach, CID product ions are dispersed in two dimensions, specifically size-to-charge (IM) and mass-to-charge (MS), and the resulting 2D data display greatly
Nathanael F, Zinnel   +2 more
openaire   +2 more sources

Identifying drug metallation sites on peptides using electron transfer dissociation (ETD), collision induced dissociation (CID) and ion mobility-mass spectrometry (IM-MS)

Chemical Communications, 2010
Electron transfer dissociation (ETD) and collision induced dissociation (CID) have been used to locate the precise binding sites for platinum and ruthenium anticancer complexes on the peptide Substance P. We show that ETD combined with ion mobility-mass spectrometry significantly reduces mass spectral complexity and improves the S/N of the product-ions
Jonathan P, Williams   +3 more
openaire   +2 more sources

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