Results 21 to 30 of about 30,983 (257)

Native ion mobility mass spectrometry reveals that small organic acid fragments impart gas‐phase stability to carbonic anhydrase II [PDF]

Rapid Communications in Mass Spectrometry, 2020
Rationale A key element of studies that utilise ion mobility mass spectrometry (IM‐MS) under native electrospray conditions for the analysis of protein–ligand binding is the maintenance of the native conformation of a protein during the removal of bulk solvent.
Clinton G.L. Veale, Maria Mateos Jimenez, C. Logan Mackay, David J. Clarke   +3 more
openaire   +2 more sources

Secret Recipe Revealed: Chemical Evaluation of Raw Colouring Mixtures from Early 19th Century Moravia

Molecules, 2022
An archaeological excavation in Prostějov (Czech Republic) revealed a workshop of a local potter with colourless, pink, and blue powders presumably used to produce faience/surface decoration. A comprehensive analytical study, which combined elemental and
Klára Jagošová, Martin Moník, Jaroslav Kapusta, Radka Pechancová, Jana Nádvorníková, Pavel Fojtík, Ondřej Kurka, Tereza Závodná, Petr Bednář, Lukáš Richtera, Lukáš Kučera   +10 more
doaj   +1 more source

Systematic Qualitative and Quantitative Analyses of Wenxin Granule via Ultra-High Performance Liquid Chromatography Coupled with Ion Mobility Quadrupole Time-of-Flight Mass Spectrometry and Triple Quadrupole–Linear Ion Trap Mass Spectrometry

Molecules, 2022
Wenxin granule (WXG) is a popular traditional Chinese medicine (TCM) preparation for the treatment of arrhythmia disease. Potent analytical technologies are needed to elucidate its chemical composition and assess the quality differences among multibatch ...
Yueguang Mi, Wandi Hu, Weiwei Li, Shiyu Wan, Xiaoyan Xu, Meiyu Liu, Hongda Wang, Quanxi Mei, Qinhua Chen, Yang Yang, Boxue Chen, Meiting Jiang, Xue Li, Wenzhi Yang, Dean Guo   +14 more
doaj   +1 more source

Design and Application of a Traveling Wave Pulse Power Supply for Traveling Wave Ion Mobility Spectrometry [PDF]

Zhipu Xuebao, 2022
Ion mobility (IM) coupled mass spectrometry (MS) is a versatile tool for analytical separations, characterization, and detection by measuring collision cross-sections and mass-to-charge (m/z) ratios.
LI Hong1, DENG Fu-long1, GUO Xing2, LYU Yan-tong3, YUE Han-lu1, WANG Ru-xin1, YANG Yan-ting4, ZHAO Zhong-jun5, DUAN Yi-xiang1   +8 more
doaj   +1 more source

Studies on the Genus Pyrenopolyporus (Hypoxylaceae) in Thailand Using a Polyphasic Taxonomic Approach

Journal of Fungi, 2023
Over the past two decades, hypoxylaceous specimens were collected from several sites in Thailand. In this study, we examined their affinity to the genus Pyrenopolyporus using macroscopic and microscopic morphological characters, dereplication of their ...
Sarunyou Wongkanoun, Boonchuai Chainuwong, Noppol Kobmoo, Sittiruk Roytrakul, Sayanh Somrithipol, Jennifer Luangsa-ard, Esteban Charria-Girón, Prasert Srikitikulchai, Marc Stadler   +8 more
doaj   +1 more source

Characterization of Structural Changes of Metallothionein by Ion Mobility-Mass Spectrometry (IM-MS): Metal-Free Vs. Metallated Forms [PDF]

Biophysical Journal, 2012
Metal ions play important roles in many chemical and biochemical processes, such as oxidation, oxygen transport, and electron transfer. The cellular trafficking of metal ions is controlled by a group of low molecular weight (6-10 kDa), cysteine-rich proteins (∼30%) referred to as metallothioneins (MTs).
Chen, Shu-Hua, Russell, David H.
openaire   +1 more source

Effects of Low Concentration Glycerol on Protein Structure Based on Ion Mobility-Mass Spectrometry [PDF]

Zhipu Xuebao, 2022
Glycerol is a simple polyol compound, it has many biological and industrial applications when mixed with water. It can stabilize proteins under extreme conditions, such as heat stress, cold shock, high pressure, etc. Most proteins are usually stored in a
HE Yuan-feng, ZHU Long-ping, MIAO Hui, CHEN Bao   +3 more
doaj   +1 more source

Important Requirements for the Selection of Internal Standards during the Development of Desorption/Ionization Assays for Drug Quantification in Biological Matrices—A Practical Example

Molecules, 2022
Desorption/ionization mass spectrometry (DI-MS) approaches allow for the rapid quantification of drugs in biological matrices using assays that can be validated according to regulatory guidelines.
Margaux Fresnais, Seda Karabulut, Yasmin Abou Zeed, Johannes Ungermann, Julia Benzel, Kristian W. Pajtler, Stefan M. Pfister, Walter E. Haefeli, Jürgen Burhenne, Rémi Longuespée   +9 more
doaj   +1 more source

Atmospheric pressure ultraviolet laser desorption and ionization from liquid samples for native mass spectrometry [PDF]

, 2019
Understanding protein structure is vital for evaluating protein interactions with drugs, proteins and other ligands. Native mass spectrometry (MS) is proving to be invaluable for this purpose, enabling analysis of ’native-like’ samples that mimic ...
Cramer, Rainer, Hale, Oliver
core   +1 more source

Evaluation of Different Tandem MS Acquisition Modes to Support Metabolite Annotation in Human Plasma Using Ultra High-Performance Liquid Chromatography High-Resolution Mass Spectrometry for Untargeted Metabolomics

Metabolites, 2020
Ultra-high performance liquid chromatography coupled to high-resolution mass spectrometry (UHPLC-HRMS) is a powerful and essential technique for metabolite annotation in untargeted metabolomic applications.
Julian Pezzatti, Víctor González-Ruiz, Julien Boccard, Davy Guillarme, Serge Rudaz   +4 more
doaj   +1 more source