Results 61 to 70 of about 2,465,079 (227)

Characterization of Amyloid Oligomers by Electrospray Ionization-Ion Mobility Spectrometry-Mass Spectrometry (ESI-IMS-MS) [PDF]

, 2016
Soluble oligomers formed during the self-assembly of amyloidogenic peptide and protein species are generally thought to be highly toxic. Consequently, thorough characterization of these species is of much interest in the quest for effective therapeutics and for an enhanced understanding of amyloid fibrillation pathways.
Scarff, CA, Ashcroft, AE, Radford, SE
openaire   +4 more sources

A Portal‐Preorganized Cucurbit[7]uril‐Ruthenium Conjugate Enables Motif‐Selective Protein Sensing

Angewandte Chemie International Edition, EarlyView.
Reprogramming cucurbit[7]uril (CB7) recognition through portal engineering transforms an optically silent host into a motif‐selective photoluminescent receptor. The portal‐preorganized CB7‐Rubpy conjugate directly reports changes in aromatic motif accessibility, enabling optical sensing of protein misfolding and refolding.
Patrick Gruhs, Albert Kraft, Vahideh Mahram, Marco Neumaier, Papri Chakraborty, Emily Janz, Maria Vittoria Balli, Pierre Picchetti, Luca Prodi, Manfred Kappes, Frank Biedermann   +10 more
wiley   +1 more source

Detection of Potato Storage Disease via Gas Analysis: A Pilot Study Using Field Asymmetric Ion Mobility Spectrometry [PDF]

, 2014
Soft rot is a commonly occurring potato tuber disease that each year causes substantial losses to the food industry. Here, we explore the possibility of early detection of the disease via gas/vapor analysis, in a laboratory environment, using a recent ...
Covington, James A., Clarkson, John P., Rutolo, Massimo, James Covington, James A. Covington, Daciana Iliescu, Iliescu, Daciana, John Clarkson, Massimo Rutolo   +8 more
core   +1 more source

Boosting Bifacial Output Power of Ag‐CIGS Solar Cells by Optimizing ITO Back‐Contact Thickness for Tandem Applications

Carbon Energy, EarlyView.
Optimized ITO back contact with pre‐Ga supply growth and Ag incorporation suppresses GaOx formation and interface recombination in bifacial CIGS solar cells. The devices achieve 17.25% front and 5.77% rear efficiency, delivering record bifacial power density up to 32.26 mW cm−2 in 4T perovskite/CIGS tandem architectures under enhanced albedo ...
Amanat Ali, Dae‐Ho Son, Wook Hyun Kim, Hyo Jeong Jo, Dong‐Hwan Jeon, Won‐Joon Kim, Van‐Quy Hoang, Jaebaek Lee, Bashiru Kadiri‐English, Jin‐Kyu Kang, Kee‐Jeong Yang, Shi‐Joon Sung, Dae‐Kue Hwang, Dae‐Hwan Kim   +13 more
wiley   +1 more source

Characterization of the Flavor Profile of Bigeye Tuna Slices Treated by Cold Plasma Using E-Nose and GC-IMS

Fishes, 2022
To avoid heat, treatment induces numerous physicochemical changes under severe conditions in the tuna, cold plasma (CP), as a non-thermal technology, possess objective potential on tuna processing.
Weicong Pan, Soottawat Benjakul, Chiara Sanmartin, Alessandra Guidi, Xiaoguo Ying, Lukai Ma, Xudong Weng, Jin Yu, Shanggui Deng   +8 more
doaj   +1 more source

FluoroMatch IM: An Interactive Software for PFAS Analysis by Ion Mobility Spectrometry

Environmental Science & Technology
Per- and polyfluoroalkyl substances (PFASs) are often present in complex mixtures at trace levels in environmental samples, posing difficulties for analytical chemists. Ion mobility offers highly replicable identifiers, enabling the use of community-based libraries for PFAS annotation in nontargeted analysis.
Rachel Smolinski, Jeremy P. Koelmel, Paul Stelben, David Weil, David Godri, David Schiessel, Michael Kummer, Sarah M. Stow, Sheher Mohsin, Lauren Royer, Alan McKenzie-Coe, Thomas Lubinsky, Daniel DeBord, Olivier Chevallier, Emma E. Rennie, Krystal J. Godri Pollitt, Carrie McDonough   +16 more
openaire   +2 more sources

Influence of Head‐to‐Tail Cyclization of Lanmodulin‐Inspired Peptides on Lanthanide Affinity and Structure

Chemistry – A European Journal, EarlyView.
The influence of head‐to‐tail cyclization, as well as the effect of ring expansion with an additional glycine on lanmodulin‐inspired peptides on the structure and lanthanide (Ln)‐binding behavior was investigated. While the decrease of structural flexibility can indeed increase the Ln affinity and peptide pre‐organization, it does not lead to an ...
Sophie M. Gutenthaler‐Tietze, Jerome Kretzschmar, Satoru Tsushima, Patrick Weis, Robin Steudtner, Björn Drobot, Lena J. Daumann   +6 more
wiley   +1 more source

Adduct ion formation as a tool for the molecular structure assessment of ten isomers in traveling wave and trapped ion mobility spectrometry

, 2019
Rationale The separation of isomeric compounds with major differences in their physiochemical and pharmacokinetic properties is of particular importance in pharmaceutical R&D.
Jordens, Jan, Cuyckens, Filip, Ynze Mengerink, Hadavi, Darya, Jan Jordens, Filip Cuyckens, Erik de Lange, Mengerink, Ynze, de Lange, Erik, Darya Hadavi, Maarten Honing, Honing, Maarten   +11 more
core   +1 more source

Orthogonal Extraction Ion Mobility Spectrometry [PDF]

, 2006
Ion Mobility Spectrometry is a powerful tool for the study of molecular conformations, separation of mass isomers, and analysis of complex mixtures and suppression of chemical background.
Laiko, Victor V.
core   +1 more source

Micro‐QuEChERS Extraction for Broad‐Spectrum LC‐QQQ‐MS Quantification of Nitazene Analogs in Plasma: A Validated Method With Casework Application

Drug Testing and Analysis, EarlyView.
Micro‐QuEChERS sample preparation coupled to LC‐QQQ‐MS enabled sensitive quantification of nitazene analogs in 100 μL of plasma. The validated method provided low detection limits and was successfully applied to an authentic intoxication case involving N‐pyrrolidino protonitazene, supporting clinical and forensic toxicology workflows.
Karla A. O. Souza, Náthaly C. B. F. Santos, Rafael Lanaro, Sara E. Walton, Alex J. Krotulski, Barry K. Logan, Mauricio Yonamine, Jose Luiz Costa   +7 more
wiley   +1 more source