Results 91 to 100 of about 1,383,826 (295)

Broadband, unpolarized repumping and clearout light sources for Sr$^+$ single-ion clocks

, 2015
Future transportable optical clocks require compact and reliable light sources. Here, broadband, unpolarized repumper and state clearout sources for Sr+ single-ion optical clocks are reported. These turn-key devices require no frequency stabilization nor
Dubé, P., Fordell, T., Lindvall, T., Madej, A. A., Merimaa, M., Wallin, A. E.   +5 more
core   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Atomistic defect states as quantum emitters in monolayer MoS$_2$

, 2019
Quantum light sources in solid-state systems are of major interest as a basic ingredient for integrated quantum device technologies. The ability to tailor quantum emission through deterministic defect engineering is of growing importance for realizing ...
Cerne, J., Finley, J., Florian, M., Holleitner, A., Kaniber, M., Klein, J., Knap, M., Lorke, M., Mitterreiter, E., Müller, K., Rey, S., Schmidt, R., Sigger, F., Sigl, L., Taniguchi, T., Watanabe, K., Wierzbowski, J., Wurstbauer, U., Zimmermann, P.   +18 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

A Platform for Laser-Driven Ion Sources Generated with Nanosecond Laser Pulses in the Intensity Range of 10¹³–10¹⁵ W/cm²

Quantum Beam Science
An experimental platform for laser-driven ion (sub-MeV) acceleration and potential applications was commissioned at the HiLASE laser facility. The auxiliary beam of the Bivoj laser system operating at a GW level peak power (~10 J in 5–10 ns) and 1–10 Hz ...
L. Giuffrida, V. Istokskaia, A. Picciotto, V. Kantarelou, M. Barozzi, R. Dell`Anna, M. Divoky, O. Denk, D. Giubertoni, F. Grepl, A. Hadjikyriacou, M. Hanus, J. Krasa, M. Kucharik, T. Levato, P. Navratil, J. Pilar, F. Schillaci, S. Stancek, M. Tosca, M. Tryus, A. Velyhan, A. Lucianetti, T. Mocek, D. Margarone   +24 more
doaj   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Ion Heating in Advanced Dielectric Barrier Discharge Ion Sources for Ambient Mass Spectrometry. [PDF]

J Am Soc Mass Spectrom, 2023
Bouza M, Ahmed E, Rocío-Bautista P, Brandt S, Franzke J, Molina-Díaz A, García-Reyes JF, Donald WA.   +7 more
europepmc   +1 more source

Single ion implantation for single donor devices using Geiger mode detectors

, 2009
Electronic devices that are designed to use the properties of single atoms such as donors or defects have become a reality with recent demonstrations of donor spectroscopy, single photon emission sources, and magnetic imaging using defect centers in ...
E Bielejec, Gramsch E Pcheliakov O P Chistokhin I B Tishkovsky E, Hopf T, J A Seamons, M S Carroll, Shinada T, The Stopping, Wu S Wu X Choa F Krainak M A   +7 more
core   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source