Results 51 to 60 of about 353,875 (266)

Multimodal luminescence spectra of ion‐implanted silica [PDF]

physica status solidi (a), 2005
AbstractThermally oxidized SiO2 layers have been implanted by oxygen and sulfur ions up to an atomic dopant fraction of about 4 at%. The cathodoluminescence spectra of these ion implanted layers show besides the characteristic bands an identical sharp and intensive multimodal structure in the green up to near IR region.
Fitting, H.-J., Salh, R., Barfels, T., Schmidt, B.   +3 more
openaire   +2 more sources

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Exploring QGP signature in small system: Insights from ALICE in p–Pb and pp collisions [PDF]

EPJ Web of Conferences
The formation of quark-gluon plasma (QGP) has been confirmed in ultra-relativistic heavy-ion (i.e. Pb-Pb) collisions. Results from small collision systems, such as proton-ion (p–Pb) and proton-proton (pp) collisions at LHC energies, have revealed several
Patra Rajendra Nath
doaj   +1 more source

Protein dynamics of a light-driven Na+ pump rhodopsin probed using a tryptophan residue near the retinal chromophore

Biophysics and Physicobiology, 2023
Direct observation of protein structural changes during ion transport in ion pumps provides valuable insights into the mechanism of ion transport. In this study, we examined structural changes in the light-driven sodium ion (Na+) pump rhodopsin KR2 on ...
Akihiro Otomo, Misao Mizuno, Keiichi Inoue, Hideki Kandori, Yasuhisa Mizutani   +4 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Origin of the turbulent spectra in the high-altitude cusp: Cluster spacecraft observations [PDF]

Annales Geophysicae, 2006
High-resolution magnetic field data from Cluster Flux Gate Magnetometer (FGM) and the Spatio-Temporal Analysis of Field Fluctuations (STAFF) instruments are used to study turbulent magnetic field fluctuations during the high-altitude cusp crossing on ...
K. Nykyri, B. Grison, P. J. Cargill, B. Lavraud, E. Lucek, I. Dandouras, A. Balogh, N. Cornilleau-Wehrlin, H. Rème   +8 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

A needle-to-post air discharge ion source in tandem with FAIMS system.

PLoS ONE, 2019
A needle-to-post ionization source was designed for high-field asymmetric waveform ion mobility spectrometry (FAIMS). The needle-to-post ion source includes asymmetric electrode comprised of a copper post with a diameter of 2 mm and a stainless-steel ...
Hua Li, Hongmei Yun, Yongrong Jiang, Ruosheng Zeng, Zhencheng Chen   +4 more
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Development of Tandem Ion Mobility Spectrometry with High-voltage Fragmentation Unit at Atmospheric Pressure for Explosives Detection

Zhipu Xuebao
Trace explosive detection is an essential aspect for ensuring public safety. Ion mobility spectrometry (IMS) is an effective technique for detecting explosives and compounds related to explosives.
Kang-yi LIU, Tian-xin XIAN, Ling-feng LI, Yun-jing ZHANG, Xing-li HE, Peng LI   +5 more
doaj   +1 more source