Results 41 to 50 of about 211,826 (293)

The DRIFT Directional Dark Matter Detector and First Studies of the Head-Tail Effect

, 2007
Measurement of the direction of the elastic nuclear recoil track and ionization charge distribution along it, gives unique possibility for unambiguous detection of the dark matter WIMP particle.
Majewski, P., Spooner, N. J. C.
core   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Space-point calibration of the ALICE TPC with track residuals [PDF]

EPJ Web of Conferences, 2020
In the LHC Run 3, starting in 2021, the upgraded Time Projection Chamber (TPC) of the ALICE experiment will record minimum bias Pb–Pb collisions in a continuous readout mode at an interaction rate up to 50 kHz.
Schmidt Marten Ole
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

A Two-Fluid Method for Ambipolar Diffusion

, 2008
We present a semi-implicit method for isothermal two-fluid ion-neutral ambipolar drift that is second-order accurate in space and time. The method has been implemented in the RIEMANN code for astrophysical fluid dynamics.
Balsara, Balsara, Balsara, Balsara, Balsara, Balsara, Balsara, Balsara, Basu, Blitz, Ciolek, Ciolek, David A. Tilley, Dinshaw S. Balsara, Draine, Draine, Falgarone, Falle, Fatuzzo, Indebetouw, Jiang, Jijina, Kudoh, Langer, Larson, Li, Li, Li, Lim, Mac Low, Mestel, Motte, Mouschovias, Mouschovias, Nakamura, O'Sullivan, O'Sullivan, Oishi, Pudritz, Roberge, Shu, Smith, Tóth, Tóth, Wardle, Zweibel   +45 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

An experimental cross-section measurement of 10B(n,α)7Li reaction on counting alpha particles track density

Iraqi Journal of Physics, 2018
The present work determines the particle size based only on the number of tracks detected in a cluster created by a hot particle on the CR-39 solid state nuclear track detector and depending on the exposure time.
Khalid R. Flyah
doaj   +1 more source

Dealing with High Background Rates in the STAR Heavy Flavor Tracker in Simulation: Embedding Simulation into Real Events [PDF]

EPJ Web of Conferences, 2020
The STAR Heavy Flavor Tracker (HFT) has enabled a rich physics program, providing important insights into heavy quark behavior in heavy ion collisions.
Webb Jason C., Lauret Jérôme, Van Buren Gene, Radhakrishnan Sooraj, Dong Xin   +4 more
doaj   +1 more source

SHI induced nano track polymer filters and characterization [PDF]

, 2009
Swift heavy ion irradiation produces damage in polymers in the form of latent tracks. Latent tracks can be enlarged by etching it in a suitable etchant and thus nuclear track etch membrane can be formed for gas permeation / purification in particular for
Vijay, Y K
core   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source