Results 101 to 110 of about 250,786 (309)
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
PRX EnergyCalculation of ionic conductivity including ion-ion correlation effects using equilibrium molecular dynamics (EMD) is computationally demanding, but the correlation is significant in many promising electrolytes such as solid electrolytes. Herein, we have
Ryoma Sasaki +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Elastic, strong and tough ionically conductive elastomers
Nature CommunicationsStretchable elastic materials with high strength, toughness, and good ionic conductivity are highly desirable for wearable devices and stretchable batteries.
Burebi Yiming +6 more
doaj +1 more source
Ionic liquids - inherent sensing and transduction of metal ion complexation [PDF]
, 2010 Ionic Liquids (IL’s) - being organic salts that are liquid at room temperature, display inherent ionic conductivity and a wide electrochemical window. This has led to their inevitable incorporation into electrochemical sensing techniques1.
Clark, Noel +4 more
core
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Fast Measurement of Methanol Concentration in Ionic Liquids by Potential Step Method
International Journal of Analytical Chemistry, 2015 The development of direct methanol fuel cells required the attention to the electrolyte. A good electrolyte should not only be ionic conductive but also be crossover resistant. Ionic liquids could be a promising electrolyte for fuel cells.
Michael L. Hainstock, Yijun Tang
doaj +1 more source
Ionic conductivity of lanthanum fluoride [PDF]
Electrical conductivity of lanthanum fluoride single crystal with calcium ...
Fielder, W. L.
core +1 more source