Results 51 to 60 of about 247,613 (303)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Oxygen permeation modelling of perovskites [PDF]

, 1992
A point defect model was used to describe the oxygen nonstoichiometry of the perovskites La0.75Sr0.25CrO3, La0.9Sr0.1FeO3, La0.9Sr0.1CoO3 and La0.8Sr0.2MnO3 as a function of the oxygen partial pressure.
Bouwmeester, Henny J.M., Dokiya, Masayuki, Hassel, Bart A. van, Kawada, Tatsuya, Sakai, Natsuko, Yokokawa, Harumi   +5 more
core   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Concentration polarization and ionic conductivity of nanocomposite thermoelectric materials K0.01Cu1.94S, K0.02Cu1.94S, K0.03Cu1.94S

Eurasian Journal of Physics and Functional Materials
The paper presents experimental results of concentration polarization and ionic conductivity of nanocomposite thermoelectric materials K0.01Cu1.94S , K0.02Cu1.94S , K0.03Cu1.94S . According to X-ray phase analysis, the synthesized samples are monoclinic
M. M. Kubenova, M. Kh. Balapanov, K. A. Kuterbekov, B. Akhmetgaliev, R. Kh. Ishembetov   +4 more
doaj   +1 more source

Experimental Study on Electrical Conductivity of FexO-CaO-SiO2-Al2O3 System at Various Oxygen Potentials

High Temperature Materials and Processes, 2018
The electrical conductivity of FexO-CaO-SiO2-Al2O3 slags was measured by a four terminal method. The results show that the temperature dependences of total, electronic and ionic conductivity for different compositions obey the Arrhenius law and all of ...
Liu Yan–Xiang, Liu Jun–Hao, Zhang Guo–Hua, Zhang Jian–Liang, Chou Kuo–Chih   +4 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Preparation of Comb-Shaped Polyether with PDMS and PEG Side Chains and Its Application in Polymer Electrolytes

Molecules
Polyethylene oxide (PEO) is the most well-studied polymer used in solid polymer electrolytes (SPEs) for lithium ion batteries (Li-ion batteries). However, ionic conductivity is greatly reduced in the low temperature range due to the crystallization of ...
Tomoya Enoki, Ryuta Kosono, Nurul Amira Shazwani Zainuddin, Takahiro Uno, Masataka Kubo   +4 more
doaj   +1 more source

Effect of grain boundary resistance on the ionic conductivity of amorphous xLi2S-(100-x)LiI binary system

Frontiers in Chemistry, 2023
Solid-state electrolytes (SSEs) hold the key position in the progress of cutting-edge all-solid-state batteries (ASSBs). The ionic conductivity of solid-state electrolytes is linked to the presence of both amorphous and crystalline phases.
Longbang Di, Jiangyang Pan, Lei Gao, Jinlong Zhu, Liping Wang, Xiaomeng Wang, Qinqin Su, Song Gao, Ruqiang Zou, Yusheng Zhao, Songbai Han   +10 more
doaj   +1 more source

Characterization and Characteristics of mechanochemically synthesized amorphous fast ionic conductor 50 SISOMO (50AgI-25Ag2O-25MoO3)

, 2012
Mechanochemically synthesized amorphous 50SISOMO [50AgI-25Ag_2O-25MoO_3] fast ionic conductor shows high ionic conductivity of ~ 6x10^-3 {\Omega}^-1 cm-1 at room temperature.
Dayal, Saurabh, Shahi, K.
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source