Results 131 to 140 of about 80,692 (280)

Shear Stress‐Stimulated Trafficking of Endothelial Piezo1 to Splenic Capsule Boosts Spleen Contraction and Exercise Endurance

Journal of Extracellular Vesicles, Volume 15, Issue 10, October 2026.
The vasculo‐splenic axis during exercise: shear stress triggers the release of medium/large extracellular vesicles from vascular endothelial cells via activation of Piezo1, shuttling Piezo1 to the smooth muscle cells in the splenic capsule; the translocated Piezo1 within the splenic capsule acts as a downstream effector of the α1‐adrenergic receptor ...
Jing Lou, Mingzong Yang, Yang Hu, Xuyun Liu, Han Li, Zihang Feng, Yuxin Xi, Changyang Xing, Lijun Yuan, Jia Li, Shengpeng Wang, Feng Gao, Xing Zhang   +12 more
wiley   +1 more source

Neutrophil Extracellular Traps in Atherosclerosis and Cardiovascular Disease

MedComm, Volume 7, Issue 10, October 2026.
NETs as integrated effectors in the atherosclerotic cardiovascular disease continuum. Activated neutrophils release NETs that promote endothelial injury, thrombo‐inflammation, and plaque destabilization throughout atherosclerotic disease progression. Created with BioRender.com.
Ji Zhang, Fangjiaqi Wei, Mengdi Qu, Yuwen Shao, Tingye Xu, Darko Stojkov, Hans‐Uwe Simon, Ben Huang, Changhong Miao, Hao Zhang   +9 more
wiley   +1 more source

Iron and Other Metal Ions in Human Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
Iron, copper, zinc, and calcium orchestrate cellular function through distinct yet cooperative mechanisms: redox‐active iron and copper cycle between oxidation states to act as Fenton catalysts and electron carriers in oxidative phosphorylation (OXPHOS); redox‐inert zinc serves as a structural component of zinc‐finger proteins and a catalytic cofactor ...
Xiaofeng Dai, Jitian Li
wiley   +1 more source

Hepatocellular Carcinoma Targeted Thermosensitive Cu2+ Liposomes Based on the Cuproptosis Mechanism

MedComm, Volume 7, Issue 10, October 2026.
This study develops galactose‐modified thermosensitive liposomes loaded with copper ions for the treatment of hepatocellular carcinoma. Combined with local tumor hyperthermia, this system delivers copper ions into tumor cells, induces cuproptosis by regulating FDX1 and DLAT expression and disrupting ROS/NADPH homeostasis, and suppresses tumor ...
Hao Yang, Hui Hou, Hong Li, Xianglong Wang, Wei Zhang, Mengsi Yin, Fuyu Zhang, Faxin Zhang, Mingyuan Li, Xiangcheng Wang, Xianggao Zhu   +10 more
wiley   +1 more source

Stereoselective synthesis of spiroketal moiety of ionophore antibiotic routiennocin

, 1998
A synthetic route to optically pure spiroketal moiety comprising C8-C20 segment of ionophore antibiotic routiennocin is ...
J.S. Yadav, B. Muralidhar, Yadav, J. S., Muralidhar, B.   +3 more
core   +1 more source

Immunomodulatory Properties of Withania somnifera: Regulation of Innate Immune Cells and Clinical Implications

Phytotherapy Research, Volume 40, Issue 10, Page 5951-5972, October 2026.
ABSTRACT Withania somnifera (L.) Dunal (WS), commonly known as Ashwagandha, is a prominent medicinal herb in Ayurveda, with extensive therapeutic potential attributed to its diverse phytochemical profile. This review critically examines the immunomodulatory properties of WS, focusing on innate immune cell populations, including neutrophils, eosinophils,
Rana Yukta, Sonalika Gupta, Gagandeep Kaur, Partha Sarathi Mondal, Milirani Das, Anagha Ranade, Alok Kumar Srivastava, Sachin Kumar, Manoj Kumar Barthwal, Madhu Dikshit   +9 more
wiley   +1 more source

Halogen Bonding Ionophore for Potentiometric Iodide Sensing

Iodide (I–) is an essential micronutrient for thyroid function. Hence, rapid and portable sensing is important for I– quantification in food and biological samples.
Angeline Y. X. Tan (11691271), Shermin S. Goh (2010640), Zhi Hao Neo (11691274), Jason Y. C. Lim (6376913), Georgina E. K. K. Seah (11691268)   +4 more
core   +1 more source

Ionophore-based ion-selective potentiometric and optical sensors

, 2003
This paper describes ion-selective electrodes (ISEs) and optodes with a focus on the fundamental mechanisms, response characteristics, and recognition elements (ionophores) described to date for these sensors.
Johnson, R Daniel, Bachas, Leonidas G
core   +1 more source

ATP Release and Purinergic Signaling Potentiate β‐Adrenergic Effects on Brown Adipocytes

Acta Physiologica, Volume 242, Issue 10, October 2026.
ABSTRACT Aim Brown adipose tissue (BAT) specializes in energy consumption and thermogenesis in response to cold stress. Brown adipocytes (BA) express purinergic receptors, yet little is known about the source of extracellular ATP and the role of purinergic signaling, and the potential interaction with β‐adrenergic signaling.
Marco Tozzi, Emilie B. Berggreen, Rui Zhang, Anders Gudiksen, Wei Li, Mathias B. Matz, Henriette Pilegaard, Jacob B. Hansen, Ivana Novak   +8 more
wiley   +1 more source

Assessment of Ion‐Ionophore Complex Diffusion Coefficients in Solvent Polymeric Membranes

, 2009
Chronoamperometric (CA) and chronopotentiometric (CP) transients have been used previously for the determination of the diffusion coefficients of free ionophores in ion-selective liquid membranes.
Klára Tóth, Justin M. Zook, Gyurcsányi, Róbert E., Róbert E. Gyurcsányi, Tóth, Klára, Sándor Bodor, Bodor, Sándor, Zook, Justin, Ernő Lindner, Lindner, Erno   +9 more
core   +1 more source