Results 131 to 140 of about 41,324 (250)

CYCLOHEXANE AS AN IONOPHORE [PDF]

open access: yes, 2003
Author Institution: Department of Chemistry, University of Illinois at Urbana ChampaignSeveral molecules based upon 1,3,5-triaxially substituted cyclohexane templates have shown promising results as ionophores.
Lisy, James M., Patwari, G. Naresh
core  

Synergistic Probe Combining Lysosome Anchoring and Tumor Defense System Targeting for Precise Tumor Visualization

open access: yesAdvanced Science, Volume 13, Issue 44, 7 August 2026.
A new generation of high‐precision fluorescent probes based on the lysosomal characteristics in tumor metabolic reprogramming and overexpressed tumor markers. The probe (CN‐D‐GGT) selectively label cancer cells in co‐culture systems and distinguish tumor lesions from inflamedand normal tissues in vivo, enabling precise tumor imaging.
Yang Shen   +6 more
wiley   +1 more source

Aditivos vs teores de concentrado na ração de bubalinos e bovinos: digestibilidade in vitro da matéria seca = Additives vs concentrate levels in rations for buffaloes and cattle: dry matter in vitro digestibility

open access: yesActa Scientiarum: Animal Sciences, 2007
Avaliou-se a digestibilidade in vitro da matéria seca (DIVMS) de rações com cinco teores de concentrado (0, 5, 10, 20 e 50%) e ausência ou presença de aditivos (raçõestestemunha, com ionóforo (Rumensin) e com probiótico (Beef-sacc)), consistindo ...
Juliano Ricardo Fontanini Beleze   +5 more
doaj  

Mercury selective electrochemical sensor based on a double armed crown ether as ionophore [PDF]

open access: yes, 2003
PVC based membranes of a double armed crown ether, N, N'-dibenzyl, 1,4,10,13-tetraoxa-7, 16-diaza cyclooctadecane (I) as ionophore with sodium tetra phenyl borate (NaTPB) as anion excluder and with many plasticizing solvent mediators have been prepared ...
Agarwal Shiva   +5 more
core  

An Energy Autonomous Microneedle Array‐Based Sensing System for Continuous Biomarker Monitoring

open access: yesAdvanced Science, Volume 13, Issue 46, 17 August 2026.
This work presents an innovative self‐powered wearable biosensor system for real‐time monitoring of multiple biomarkers in interstitial fluid. The device integrates stainless steel‐based minimally invasive microneedles with ion‐selective membranes, enabling simultaneous Na+, K+, Ca2+, pH, and glucose detection.
Arnab Pal   +9 more
wiley   +1 more source

A Tale of Two Mechanisms: The p53 Modulator COTI‐2 Is a Zn Metallochaperone

open access: yesDrug Development Research, Volume 87, Issue 5, August 2026.
ABSTRACT Mutations in, or misregulation of, Tp53 are found in approximately 50% of all cancers. p53 functions by ensuring that cells with irretrievably damaged DNA undergo apoptosis. Tp53 mutations often induce conformational changes that inhibit activity; however, small‐molecule chaperones could theoretically restore conformation and activity. COTI‐2,
İrem Şimşek   +16 more
wiley   +1 more source

ATP7A Orchestrates Tumor Progression and Cuproptosis in Hepatocellular Carcinoma via the LINC02038‐miR‐506‐3p Regulatory Circuit

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
In hepatocellular carcinoma (HCC), upregulated LINC02038 acts as a competing endogenous RNA (ceRNA) that sponges tumor‐suppressive miR‐506‐3p, leading to derepression of ATP7A expression. Elevated ATP7A subsequently promotes HCC cell proliferation, migration, and invasion, while simultaneously modulating cuproptosis sensitivity. ABSTRACT Hepatocellular
Zhe Liu   +4 more
wiley   +1 more source

Calcium ionophore A23187 versus progesterone: induction of acrosome reaction in thawed and prepared cryopreserved semen samples [PDF]

open access: yes
Background: Acrosome reaction facilitates fertilization and it can be induced in-vitro using various stimuli like progesterone, calcium ionophore A23187, prostaglandins, etc.
Arunkumar, Sowbarnika   +2 more
core   +2 more sources

Beyond a Metabolite: Lactylation as a Pivotal Regulator of Colorectal Cancer Pathogenesis and Treatment Resistance

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
This review elucidates how lactylation, a novel histone modification driven by lactate, regulates colorectal cancer pathogenesis. We summarize its roles in tumor progression, metastasis, stemness, immunosuppression, and therapy resistance, and discusses the promising therapeutic strategies of targeting the lactylation pathway.
Shuilan Yao   +4 more
wiley   +1 more source

Stress‐Induced Switch in Small Extracellular Vesicle Secretion: From Constitutive ‘Torn Bag Mechanism’ to Exocytosis

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 8, August 2026.
Stress‐induced switch. Under stress conditions, small extracellular vesicle release shifts from the constitutive ‘torn bag mechanism’ to exocytosis of multivesicular endosomes. https://BioRender.com/xn1pa1e. ABSTRACT The biogenesis of small extracellular vesicles (sEVs) is only partially understood.
Dorina Lenzinger   +18 more
wiley   +1 more source

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