Results 141 to 150 of about 80,692 (280)

FDX1 Depletion Activates CD8+ T Cell Antitumor Immunity by Promoting DMBT1 Secretion in Cuproptosis of Colorectal Cancer

Cancer Science, Volume 117, Issue 10, Page 2659-2675, October 2026.
Elesclomol‐induced cuproptosis potently activates both innate and adaptive antitumor immunity, especially CD8+ T cell immunity. FDX1 serves as a central regulator of CD8+ T cell functionality through DMBT1 downregulation during cuproptosis in colorectal cancer.
Jieqiong Wu, Zaixi Lian, Mingzhou Li, Xingtu Qin, Xiaoyu Lei, Lihua Yang, Lin Bing, Qiuyue Li, Lingyan Zhou, Zhiyang Ma, Xuemei Xu, Jinghao Huang, Zilong Chen, Lijie Chen, Lingjie Zhang, Zhiyuan Xiao, Xiangyu Jian, Xiaoqin Zhang, Yanqing Ding, Yaping Ye, Li Liang, Hongli Jiao, Shuyang Wang   +22 more
wiley   +1 more source

Effects of Monensin, Calcareous Algae, and Essential Oils on Performance, Carcass Traits, and Methane Emissions Across Different Breeds of Feedlot-Finished Beef Cattle

Ruminants
With the growing use of crossbred cattle in Brazilian feedlots and increasing pressure to reduce antibiotic use as growth promoters, this study examines the impact of three feed additives—monensin (MON), monensin with Lithothamnium calcareum (LCM), and a
Pedro Guerreiro, Diogo F. A. Costa, Arnaldo C. Limede, Guilhermo F. S. Congio, Murillo A. P. Meschiatti, Priscila A. Bernardes, Flavio A. Portela Santos   +6 more
doaj   +1 more source

Novel amphi-ionophore in aqueous solution: Cyclohexaalanyl

, 2018
To find a novel amphi-ionophore which strongly binds a cation or an anion alternatively in aqueous solution, we have investigated the host-guest complexation of a cyclohexapeptide composed of six alanine molecules with either alkali metal ions or halide ...
Son, HS, U, JS, Suh, SB, Cui, CZ, Won, Y, Kim, KS   +5 more
core   +1 more source

A Review of Nonsteroidal Anti‐Inflammatory Drugs for Food‐Producing Animals With a Focus on Potential Applications for Farmed Finfish

Journal of Fish Diseases, Volume 49, Issue 10, October 2026.
ABSTRACT In finfish aquaculture, there are several inflammatory diseases impacting productivity and animal welfare, however there are limited options available to veterinarians to treat inflammation and pain in fish. Nonsteroidal anti‐inflammatory drugs (NSAIDs) are widely used in terrestrial animals raised for human consumption to treat a range of ...
Chloe J. English, Christine Huynh, William Roy, James W. Wynne, Hamish Rodger   +4 more
wiley   +1 more source

Discovery of Ro 41‐0960, a Non‐Steroidal Inhibitor of the Na+/K+‐ATPase

ChemMedChem, Volume 21, Issue 17, 14 September 2026.
Ro 41‐0960 is a non‐steroidal Na+/K+‐ATPase inhibitor with low micromolar potency and a mixed inhibitory mechanism distinct from classical cardiotonic steroids, without acute pro‐arrhythmic effects in human cardiomyocytes. The Na+/K+‐ATPase (NKA) is a central regulator of cardiac ion homeostasis and a validated target for heart failure.
Carlos Cruz‐Cortés, Jaroslava Šeflová, Guadalupe Guerrero‐Serna, Eric N. Jimenez‐Vazquez, Justus Anumonwo, L. Michel Espinoza‐Fonseca   +5 more
wiley   +1 more source

Aditivos vs teores de concentrado na ração de bubalinos e bovinos: digestibilidade in vitro da matéria seca = Additives vs concentrate levels in rations for buffaloes and cattle: dry matter in vitro digestibility

Acta Scientiarum: Animal Sciences, 2007
Avaliou-se a digestibilidade in vitro da matéria seca (DIVMS) de rações com cinco teores de concentrado (0, 5, 10, 20 e 50%) e ausência ou presença de aditivos (raçõestestemunha, com ionóforo (Rumensin) e com probiótico (Beef-sacc)), consistindo ...
Juliano Ricardo Fontanini Beleze, Lucia Maria Zeoula, Guido Jacobi, Sergio Luiz Candêo Filho, Ricardo Kazama, Meiby Carneiro de Paula   +5 more
doaj  

Calcium ionophore and acetylcholine dilate arterioles on the mouse brain by different mechanisms.

, 1989
Pial arterioles on the surface of the mouse brain were observed in vivo under a chamber with a glass window. When placed under the window, calcium ionophore, acetylcholine, and previously acidified sodium nitrite each dilated the arterioles.
W I Rosenblum, B Wormley, M McDonald
core   +1 more source

A Generalized Model for Apparently “Non-Nernstian” Equilibrium Responses of Ionophore-Based Ion-Selective Electrodes. 1. Independent Complexation of the Ionophore with Primary and Secondary Ions

, 2016
A generalized model that describes apparently “non-Nernstian” equilibrium responses of ionophore-based ion-selective electrodes (ISEs) is presented.
Kazunori Odashima (2305357), Philippe Bühlmann (2465107), Shigeru Amemiya (1423084)   +2 more
core   +1 more source

CYCLOHEXANE AS AN IONOPHORE

, 2003
Author Institution: Department of Chemistry, University of Illinois at Urbana ChampaignSeveral molecules based upon 1,3,5-triaxially substituted cyclohexane templates have shown promising results as ionophores.
Lisy, James M., Patwari, G. Naresh
core   +1 more source

Physiology of ionophore transport of potassium and sodium ions across cell membranes: valinomycin and 18-crown-6 ether

Int. J. Comput. Biol. Drug Des., 2016
C. Fong
semanticscholar   +1 more source