Results 11 to 20 of about 8,661 (178)
Transdermal drug administration presents several advantages and it is therefore favorable as an alternative drug delivery route. However, transdermal delivery of biopharmaceutical drugs is made difficult by the skin barrier.
Gyubin Noh +8 more
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Background Iontophoresis had been widely used as a therapeutic option in the field of dermatology and physiotherapy. In vascular medicine, vasodilating response to acetylcholine (ACh) iontophoresis had been also previously studied in the evaluation of ...
Ibrahim Ismail Abu Zaid +5 more
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Iontophoresis is the process of increasing the penetration of drugs into the skin by application of an electric current. The drug is applied under an electrode of the same charge as the drug, and a return electrode opposite in charge to the drug is placed at a neutral site on the body surface.
Reena Rai, C. R. Srinivas
openaire +2 more sources
Electrically and Ultrasonically Enhanced Transdermal Delivery of Methotrexate
In this study, we used sonophoresis and iontophoresis to enhance the in vitro delivery of methotrexate through human cadaver skin. Iontophoresis was applied for 60 min at a 0.4 mA/sq·cm current density, while low-frequency sonophoresis was applied
Hiep X. Nguyen, Ajay K. Banga
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Iontophoretic Drug Delivery in the Oral Cavity
Iontophoresis is a noninvasive method to enhance systemic and local drug delivery by the application of an electric field. For systemic drug delivery in the oral cavity, iontophoresis was studied primarily for transbuccal delivery.
Apipa Wanasathop, S. Kevin Li
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Selected Medicines Used in Iontophoresis
Iontophoresis is a non-invasive method of systemic and local drug delivery using an electric field. Iontophoresis enables diffusion of the selected drug via skin, mucosa, enamel, dentin, and other tissues. The amount of delivered therapeutic molecules is
Tomasz M. Karpiński
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Few studies have assessed the application and side effects of potassium iodide (KI) iontophoresis. Using a double-blinded randomized controlled trial with a 1:1 parallel-group, we investigated the effect of galvanization and the KI iontophoresis in the ...
Jolanta Zwolińska +3 more
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Permeation Effect Analysis of Drug Using Raman Spectroscopy for Iontophoresis
Iontophoresis technology could improve the efficiency of transdermal drug delivery through the skin and be a promising prospective tool for clinical drug therapy in the near future.
Jiachen Bi +5 more
doaj +1 more source
Iontophoresis of endothelin receptor antagonists in rats and men. [PDF]
The treatment of scleroderma-related digital ulcers is challenging. The oral endothelin receptor antagonist (ERA) bosentan has been approved but it may induce liver toxicity.
Matthieu Roustit +9 more
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Nanoemulsion as a Platform for Iontophoretic Delivery of Lipophilic Drugs in Skin Tumors
Lipophilic drugs do not usually benefit from iontophoresis mainly because they do not solubilize in aqueous formulations suitable for the application of electric current. To explore the influence of iontophoresis on penetration of these drugs, a cationic
Luciana Facco Dalmolin +1 more
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