Results 1 to 10 of about 3,724 (119)

Transdermal Delivery of Drugs with Microneedles—Potential and Challenges

Pharmaceutics, 2015
Transdermal drug delivery offers a number of advantages including improved patient compliance, sustained release, avoidance of gastric irritation, as well as elimination of pre-systemic first-pass effect.
Kevin Ita
exaly   +3 more sources

Systematic Review on the Effectiveness of Essential and Carrier Oils as Skin Penetration Enhancers in Pharmaceutical Formulations

Scientia Pharmaceutica, 2022
Oils, including essential oils and their constituents, are widely reported to have penetration enhancement activity and have been incorporated into a wide range of pharmaceutical formulations.
Bahjat Alhasso, Muhammad Usman Ghori, Barbara R. Conway   +2 more
doaj   +1 more source

Efektivitas Patch Transdermal Ekstrak Etanol Daun Insulin (Smallanthus sonchifolius) Terhadap Kadar Glukosa Darah dan Histopatologi Pankreas Tikus Putih

JPSCR: Journal of Pharmaceutical Science and Clinical Research, 2023
Diabetes melitus adalah penyakit metabolik yang ditandai dengan hiperglikemia akibat kelainan sekresi insulin, kerja insulin atau keduanya. Salah satu permasalahan yang dihadapi dalam pengobatan pasien diabetes adalah kepatuhan terhadap terapi obat. Daun
Ni Putu Pirna Wijayanti, Lucia Hendriati, Iwan Sahrial Hamid, Teguh Widodo, Suryo Kuncorojakti   +4 more
doaj   +1 more source

The Optimization of a Dimenhydrinate Transdermal Patch Formulation Based on the Quantitative Analysis of In Vitro Release Data by DDSolver through Skin Penetration Studies

Scientia Pharmaceutica, 2021
Dimenhydrinate is an over-the-counter medication that is used to relieve nausea, vomiting, and vertigo caused by motion sickness. It has a short elimination half-life, possibly due to its first-pass metabolism.
Bazigha K. Abdul Rasool, Amira A. Mohammed, Yasmein Y. Salem   +2 more
doaj   +1 more source

Ibuprofen-Loaded Chitosan–Lipid Nanoconjugate Hydrogel with Gum Arabic: Green Synthesis, Characterisation, In Vitro Kinetics Mechanistic Release Study and PGE2 Production Test

Gels, 2021
Ibuprofen is a well-known non-steroidal anti-inflammatory (NSAID) medicine that is often used to treat inflammation in general. When given orally, it produces gastrointestinal issues which lead to lower patient compliance.
Syed Mahmood, Samah Hamed Almurisi, Khater AL-Japairai, Ayah Rebhi Hilles, Walla Alelwani, Azzah M. Bannunah, Farhan Alshammari, Fawaz Alheibshy   +7 more
doaj   +1 more source

Effect of Penetration Enhancers on Transdermal Delivery of Oxcarbazepine, an Antiepileptic Drug Using Microemulsions

Pharmaceutics, 2023
Oxcarbazepine (OXC) is an anticonvulsant drug, indicated for the treatment of the neurological disorder, epilepsy. The objective of the present study was to evaluate the transdermal delivery of OXC from microemulsions using different penetration ...
Amitkumar Virani, Vinam Puri, Hana Mohd, Bozena Michniak-Kohn   +3 more
doaj   +1 more source

O/W microemulsion droplets diffuse through hydrogel network to achieve enhanced transdermal drug delivery

Drug Delivery, 2021
To overcome the poor water solubility of total flavones of Arisaematis rhizoma, microemulsions (MEs) can be used as a carrier for transdermal administration to promote their solubilization and skin permeability.
Lina Shen, Xiaolin Hou, Zhi Wang, Teng Guo, Zehui He, Shuyao Ruan, Zhenda Liu, Hang Ruan, Yongtai Zhang, Nianping Feng   +9 more
doaj   +1 more source

The effect of transdermal flunixin meglumine on blood cortisol levels in dairy calves after cautery disbudding with local anesthesia

Journal of Dairy Science, 2022
: The objective of this study was to evaluate the effect of the nonsteroidal anti-inflammatory drug transdermal flunixin meglumine (Finadyne Transdermal) on plasma cortisol, average daily weight gain, and standing and lying behavior of calves, when given
M. Röder, W. Heuwieser, S. Borchardt, J.L. Plenio, R. Palme, F. Sutter   +5 more
doaj   +1 more source

Transdermal estrogen gel vs oral estrogen after hysteroscopy for intrauterine adhesion separation: A prospective randomized study

Frontiers in Endocrinology, 2023
BackgroundThis randomized controlled trial (RCT) aimed to compare two different routes of postoperative estrogen treatment on the improvements of menstruation, postoperative endometrial thickness, and fertility outcomes in patients with moderate to ...
Tianjin Yi, Tianjin Yi, Xiaofang Zhang, Xiaofang Zhang, Vani Gupta, Li Li, Li Li, Qian Zhong, Qian Zhong   +8 more
doaj   +1 more source

Ion-Pair Compounds of Strychnine for Enhancing Skin Permeability: Influencing the Transdermal Processes In Vitro Based on Molecular Simulation

Pharmaceuticals, 2021
This research aimed to explore how Strychnine (Str) ion-pair compounds affect the in vitro transdermal process. In order to prevent the influence of different functional groups on skin permeation, seven homologous fatty acids were selected to form ion ...
Lili He, Di Xiong, Lan Ma, Yan Liang, Teng Zhang, Zhiming Wu, Huaibo Tang, Xuewen Wu   +7 more
doaj   +1 more source