Results 1 to 10 of about 48,104 (161)

Enhancement strategies for transdermal drug delivery systems: current trends and applications

Drug Delivery and Translational Research, 2021
Transdermal drug delivery systems have become an intriguing research topic in pharmaceutical technology area and one of the most frequently developed pharmaceutical products in global market.
Ryan F Donnelly, Aaron J Courtenay, Delly Ramadon   +2 more
exaly   +2 more sources

Enhancing Permeation of Drug Molecules Across the Skin via Delivery in Nanocarriers: Novel Strategies for Effective Transdermal Applications

Frontiers in Bioengineering and Biotechnology, 2021
The transdermal route of administration provides numerous advantages over conventional routes i.e., oral or injectable for the treatment of different diseases and cosmetics applications.
Yi-Qun Yu, Yi-Qun Yu, Xue Yang, Xiao-Fang Wu, Yi-Bin Fan   +4 more
doaj   +2 more sources

Non-invasive transdermal delivery of biomacromolecules with fluorocarbon-modified chitosan for melanoma immunotherapy and viral vaccines

Nature Communications
Transdermal drug delivery has been regarded as an alternative to oral delivery and subcutaneous injection. However, needleless transdermal delivery of biomacromolecules remains a challenge.
Wenjun Zhu, Ting Wei, Yuchun Xu, Qiutong Jin, Yu Chao, Jiaqi Lu, Jun Xu, Jiafei Zhu, Xiaoying Yan, Muchao Chen, Qian Chen, Zhuang Liu   +11 more
doaj   +2 more sources

Microneedles: A smart approach and increasing potential for transdermal drug delivery system

Biomedicine and Pharmacotherapy, 2019
The most widely used methods for transdermal administration of the drugs are hypodermic needles, topical creams, and transdermal patches. The effect of most of the therapeutic agents is limited due to the stratum corneum layer of the skin, which serves ...
Gaurav Gupta, Murali Monohar Pandey, Kamal Dua   +2 more
exaly   +2 more sources

Mechanism and Application of Chitosan and Its Derivatives in Promoting Permeation in Transdermal Drug Delivery Systems: A Review

Pharmaceuticals, 2022
The mechanisms and applications of chitosan and its derivatives in transdermal drug delivery to promote drug permeation were reviewed in this paper.
Jinqian Ma, Yuchen Wang, Rong Lu
exaly   +2 more sources

Nanoemulsion: A Review on Mechanisms for the Transdermal Delivery of Hydrophobic and Hydrophilic Drugs

Scientia Pharmaceutica, 2019
Nanoemulsions (NEs) are colloidal dispersions of two immiscible liquids, oil and water, in which one is dispersed in the other with the aid of a surfactant/co-surfactant mixture, either forming oil-in-water (o/w) or water-in-oil (w/o) nanodroplets ...
Dalia S. Shaker, Rania A. H. Ishak, Amira Ghoneim, Muaeid A. Elhuoni   +3 more
doaj   +2 more sources

Microneedle arrays as transdermal and intradermal drug delivery systems: Materials science, manufacture and commercial development

Materials Science and Engineering Reports, 2016
Transdermal drug delivery offers a number of advantages for the patient, due not only its non-invasive and convenient nature, but also factors such as avoidance of first pass metabolism and prevention of gastrointestinal degradation.
Ryan F Donnelly, Rebecca E M Lutton, Eneko Larrañeta   +2 more
exaly   +2 more sources

Systematic Review on the Effectiveness of Essential and Carrier Oils as Skin Penetration Enhancers in Pharmaceutical Formulations

Scientia Pharmaceutica, 2022
Oils, including essential oils and their constituents, are widely reported to have penetration enhancement activity and have been incorporated into a wide range of pharmaceutical formulations.
Bahjat Alhasso, Muhammad Usman Ghori, Barbara R. Conway   +2 more
doaj   +1 more source

Efektivitas Patch Transdermal Ekstrak Etanol Daun Insulin (Smallanthus sonchifolius) Terhadap Kadar Glukosa Darah dan Histopatologi Pankreas Tikus Putih

JPSCR: Journal of Pharmaceutical Science and Clinical Research, 2023
Diabetes melitus adalah penyakit metabolik yang ditandai dengan hiperglikemia akibat kelainan sekresi insulin, kerja insulin atau keduanya. Salah satu permasalahan yang dihadapi dalam pengobatan pasien diabetes adalah kepatuhan terhadap terapi obat. Daun
Ni Putu Pirna Wijayanti, Lucia Hendriati, Iwan Sahrial Hamid, Teguh Widodo, Suryo Kuncorojakti   +4 more
doaj   +1 more source

The Optimization of a Dimenhydrinate Transdermal Patch Formulation Based on the Quantitative Analysis of In Vitro Release Data by DDSolver through Skin Penetration Studies

Scientia Pharmaceutica, 2021
Dimenhydrinate is an over-the-counter medication that is used to relieve nausea, vomiting, and vertigo caused by motion sickness. It has a short elimination half-life, possibly due to its first-pass metabolism.
Bazigha K. Abdul Rasool, Amira A. Mohammed, Yasmein Y. Salem   +2 more
doaj   +1 more source