Results 11 to 20 of about 107,649 (340)

Targeted-Penetrating Biomimetic Hybrid Transfersomes for Enhanced Transdermal Gene Transfection in Hypertrophic Scar Therapy. [PDF]

open access: yesAdv Sci (Weinh)
Hypertrophic scar fibroblasts membrane‐hybridized cationic transfersomes enable efficient loading and transdermal delivery of TGF‐β1 siRNA through multiple skin penetration pathways. The biomimetic platform enhances homotypic targeting, transfection, and immune evasion, suppresses TGF‐β1‐driven fibrotic signaling, and reduces extracellular matrix ...
Xing H   +9 more
europepmc   +2 more sources

Different effects of oral and transdermal hormone replacement therapies on Factor IX, APC resistance, t-PA, PAI and C- reactive protein - a cross-sectional population survey [PDF]

open access: yes, 2001
The effects of hormone replacement therapy (HRT) on thrombosis risk, thrombotic variables, and the inflammatory marker C- reactive protein (CRP) may vary by route of administration (oral versus transdermal).
Lowe, G.D.O.   +5 more
core   +8 more sources

Development of an optimised application protocol for sonophoretic transdermal delivery of a model hydrophilic drug [PDF]

open access: yes, 2011
It has now been known for over a decade that low frequency ultrasound can be used to effectively enhance transdermal drug penetration - an approach termed sonophoresis.
Abdul, Rasool   +2 more
core   +4 more sources

Ibuprofen-Loaded Chitosan–Lipid Nanoconjugate Hydrogel with Gum Arabic: Green Synthesis, Characterisation, In Vitro Kinetics Mechanistic Release Study and PGE2 Production Test

open access: yesGels, 2021
Ibuprofen is a well-known non-steroidal anti-inflammatory (NSAID) medicine that is often used to treat inflammation in general. When given orally, it produces gastrointestinal issues which lead to lower patient compliance.
Syed Mahmood   +7 more
doaj   +1 more source

Current Advances in Lipid Nanosystems Intended for Topical and Transdermal Drug Delivery Applications

open access: yesPharmaceutics, 2023
Skin delivery is an exciting and challenging field. It is a promising approach for effective drug delivery due to its ease of administration, ease of handling, high flexibility, controlled release, prolonged therapeutic effect, adaptability, and many ...
Nakamwi Akombaetwa   +5 more
semanticscholar   +1 more source

Effect of Penetration Enhancers on Transdermal Delivery of Oxcarbazepine, an Antiepileptic Drug Using Microemulsions

open access: yesPharmaceutics, 2023
Oxcarbazepine (OXC) is an anticonvulsant drug, indicated for the treatment of the neurological disorder, epilepsy. The objective of the present study was to evaluate the transdermal delivery of OXC from microemulsions using different penetration ...
Amitkumar Virani   +3 more
doaj   +1 more source

Advanced nanocarrier- and microneedle-based transdermal drug delivery strategies for skin diseases treatment

open access: yesTheranostics, 2022
Skin diseases are the fourth leading cause of nonfatal and chronic skin diseases, acting as a global burden and affecting the world economy. Skin diseases severely impact the patients' quality of life and have influenced their physical and mental state ...
Fei Qu, Rui Geng, Yijing Liu, Jintao Zhu
semanticscholar   +1 more source

O/W microemulsion droplets diffuse through hydrogel network to achieve enhanced transdermal drug delivery

open access: yesDrug Delivery, 2021
To overcome the poor water solubility of total flavones of Arisaematis rhizoma, microemulsions (MEs) can be used as a carrier for transdermal administration to promote their solubilization and skin permeability.
Lina Shen   +9 more
doaj   +1 more source

Pharmacokinetic studies for the development of transdermal drug delivery systems [PDF]

open access: yes, 2007
PhDThis thesis mainly describes a series of Phase I pharmacokinetic studies conducted on the TDS®d elivery systemw hich combinedw ith lidocaine,t estosteronea, nd a new drug, Melanotan-I for the transdermal drug delivery.
Chik, Zamri
core   +4 more sources

Recent Advancement of Medical Patch for Transdermal Drug Delivery

open access: yesMedicina, 2023
Transdermal patches are a non-invasive method of drug administration. It is an adhesive patch designed to deliver a specific dose of medication through the skin and into the bloodstream throughout the body.
W. Wong   +3 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy