Results 21 to 30 of about 3,724 (119)

Design, Development, and Evaluation of Treprostinil Embedded Adhesive Transdermal Patch

open access: yesPharmaceutics, 2023
Clinical application of treprostinil in pulmonary arterial hypertension is hampered by adverse effects caused by its high dosing frequency. The objective of this investigation was to Formulate an adhesive-type transdermal patch of treprostinil and ...
Ibrahim Alissa   +7 more
doaj   +1 more source

Development of Topical/Transdermal Self-Emulsifying Drug Delivery Systems, Not as Simple as Expected

open access: yesScientia Pharmaceutica, 2020
Self-emulsifying drug delivery systems (SEDDSs) originated as an oral lipid-based drug delivery system with the sole purpose of improving delivery of highly lipophilic drugs.
Daniélle van Staden   +2 more
doaj   +1 more source

Transdermal buprenorphine for pain management in children

open access: yesDrugs in Context, 2021
Pain is one of the main symptoms reported by sick children, particularly by those suffering from cancer. Opioids are very useful in controlling this symptom but they are burdened with significant side effects that limit their use in children ...
Giorgio Attinà   +5 more
doaj   +1 more source

Effect of Crosslinking Agent Concentration on the Properties of Unmedicated Hydrogels

open access: yesPharmaceutics, 2015
Novel polyethylene oxide (PEO) hydrogel films were synthesized via UV crosslinking with varying concentrations of pentaerythritol tetra-acrylate (PETRA) as crosslinking agent.
Rachel Shet Hui Wong   +2 more
doaj   +1 more source

Angiotensin-Neprilysin Inhibitor Therapy: A Retrospective Chart Study

open access: yesINNOVATIONS in Pharmacy
Background: Guideline-directed medical therapy in patients with systolic heart failure (HF) has demonstrated improvement in morbidity and mortality rates.
Roda Plakogiannis   +3 more
doaj   +1 more source

Continuous Drug Release by Sea Anemone Nematostella vectensis Stinging Microcapsules

open access: yesMarine Drugs, 2014
Transdermal delivery is an attractive option for drug delivery. Nevertheless, the skin is a tough barrier and only a limited number of drugs can be delivered through it. The most difficult to deliver are hydrophilic drugs.
Yossi Tal   +5 more
doaj   +1 more source

TRANSDERMAL NITROGLYCERIN

open access: yesThe Lancet, 1984
The Lancet 324 (1984) 990-990. doi:10.1016/S0140-6736(84)91214-5 ; Received by publisher: 0000-01-01 ; Harvest Date: 2016-01-04 12:21:14 ; DOI:10.1016/S0140-6736(84)91214-5 ; Page Range: 990 ...
Division of Clinical Pharmacokinetics, J. Hillis Miller Health Center, University of Florida, Gainesville, Florida 32610, U.S.A. ( host institution )   +1 more
openaire   +3 more sources

Solid Microneedles for Transdermal Delivery of Amantadine Hydrochloride and Pramipexole Dihydrochloride

open access: yesPharmaceutics, 2015
The aim of this project was to study the influence of microneedles on transdermal delivery of amantadine hydrochloride and pramipexole dihydrochloride across porcine ear skin in vitro.
Mylien T. Hoang   +2 more
doaj   +1 more source

Non-invasive transdermal delivery of biomacromolecules with fluorocarbon-modified chitosan for melanoma immunotherapy and viral vaccines

open access: yesNature Communications
Transdermal drug delivery has been regarded as an alternative to oral delivery and subcutaneous injection. However, needleless transdermal delivery of biomacromolecules remains a challenge.
Wenjun Zhu   +11 more
doaj   +1 more source

Cyclodextrins in delivery systems: Applications

open access: yesJournal of Pharmacy and Bioallied Sciences, 2010
Cyclodextrins (CDs) are a family of cyclic oligosaccharides with a hydrophilic outer surface and a lipophilic central cavity. CD molecules are relatively large with a number of hydrogen donors and acceptors and, thus in general, they do not permeate ...
Gaurav Tiwari, Ruchi Tiwari, Awani K Rai
doaj   +1 more source

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