Results 31 to 40 of about 55,857 (266)

Development of an optimised application protocol for sonophoretic transdermal delivery of a model hydrophilic drug

, 2011
It has now been known for over a decade that low frequency ultrasound can be used to effectively enhance transdermal drug penetration - an approach termed sonophoresis.
Abdul, Rasool, Omar Sarheed, Sarheed, O.A., Bazigha, K.   +3 more
core   +1 more source

Fabrication and testing of polymer microneedles for transdermal drug delivery [PDF]

, 2022
Microneedle (MN) patches have considerable potential for medical applications such as transdermal drug delivery, point-of-care diagnostics, and vaccination.
Prewett, Philip D., Prewett, Philip D, Ebrahiminejad, Vahid, Davies, Graham J, Davies, Graham J., Faraji Rad, Zahra   +5 more
core   +1 more source

Continuous Drug Release by Sea Anemone Nematostella vectensis Stinging Microcapsules

Marine Drugs, 2014
Transdermal delivery is an attractive option for drug delivery. Nevertheless, the skin is a tough barrier and only a limited number of drugs can be delivered through it. The most difficult to deliver are hydrophilic drugs.
Yossi Tal, Ari Ayalon, Agnesa Sharaev, Zoya Kazir, Vera Brekhman, Tamar Lotan   +5 more
doaj   +1 more source

Transdermal Delivery of Drugs with Microneedles—Potential and Challenges

Pharmaceutics, 2015
Transdermal drug delivery offers a number of advantages including improved patient compliance, sustained release, avoidance of gastric irritation, as well as elimination of pre-systemic first-pass effect.
Kevin Ita
doaj   +1 more source

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs, Marcel Naumann, Annaliis Lehto, Hanna Schön, Jens Kurth, Johannes Prudlo, Andreas Hermann, Elisabeth Kasper   +7 more
wiley   +1 more source

Non-invasive transdermal delivery of biomacromolecules with fluorocarbon-modified chitosan for melanoma immunotherapy and viral vaccines

Nature Communications
Transdermal drug delivery has been regarded as an alternative to oral delivery and subcutaneous injection. However, needleless transdermal delivery of biomacromolecules remains a challenge.
Wenjun Zhu, Ting Wei, Yuchun Xu, Qiutong Jin, Yu Chao, Jiaqi Lu, Jun Xu, Jiafei Zhu, Xiaoying Yan, Muchao Chen, Qian Chen, Zhuang Liu   +11 more
doaj   +1 more source

Solid Microneedles for Transdermal Delivery of Amantadine Hydrochloride and Pramipexole Dihydrochloride

Pharmaceutics, 2015
The aim of this project was to study the influence of microneedles on transdermal delivery of amantadine hydrochloride and pramipexole dihydrochloride across porcine ear skin in vitro.
Mylien T. Hoang, Kevin B. Ita, Daniel A. Bair   +2 more
doaj   +1 more source

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

Arthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source

Transdermal electromotive administration of verapamil and dexamethasone for Peyronie's disease

, 2003
Objective To evaluate the effects of the transdermal electromotive administration of verapamil and dexamethasone on plaque size, penile deviation, pain, erectile function and capacity for vaginal penetration in patients with Peyronie's disease.
S.M. Di Stasi, Virgili, G, Vespasiani, G, Giannantoni, A, E.A. Jannini, G. Capelli, Capelli G, G. Virgili, Di Stasi, SM, Capelli, G, L. Storti, Vespasiani G. Transdermal, GIANNANTONI, Antonella, Virgili G, G. Vespasiani, VESPASIANI, GIUSEPPE, DI STASI, SAVINO MAURO, JANNINI, EMMANUELE ANGELO FRANCESCO, Jannini, EA, A. Giannantoni, Jannini EA, Di Stasi SM, Storti, L, VIRGILI, GUIDO, Capelli, Giovanni   +24 more
core   +1 more source

Rheumatoid Arthritis and Coronary Artery Calcium Progression: A Case Cohort Analysis From ELSA‐Brasil

Arthritis Care &Research, EarlyView.
Objective To investigate the association between rheumatoid arthritis (RA) and coronary artery calcium (CAC) prevalence, incidence, and progression over four years in adults without prior cardiovascular disease. Methods A case‐cohort study within the Brazilian Longitudinal Study of Adult Health (ELSA‐Brasil) included 585 participants (86 patients with ...
Patrícia Fonseca Estrada, Marcos Rafael N. Cavalcante, Itamar de Souza Santos, Márcio S. Bittencourt, Vandrize Meneghini, Paulo A. Lotufo, Alessandra C. Goulart, Isabela M. Bensenor   +7 more
wiley   +1 more source