Results 51 to 60 of about 107,649 (340)

Design, Development, and Evaluation of Treprostinil Embedded Adhesive Transdermal Patch

open access: yesPharmaceutics, 2023
Clinical application of treprostinil in pulmonary arterial hypertension is hampered by adverse effects caused by its high dosing frequency. The objective of this investigation was to Formulate an adhesive-type transdermal patch of treprostinil and ...
Ibrahim Alissa   +7 more
doaj   +1 more source

Development of Topical/Transdermal Self-Emulsifying Drug Delivery Systems, Not as Simple as Expected

open access: yesScientia Pharmaceutica, 2020
Self-emulsifying drug delivery systems (SEDDSs) originated as an oral lipid-based drug delivery system with the sole purpose of improving delivery of highly lipophilic drugs.
Daniélle van Staden   +2 more
doaj   +1 more source

Transdermal buprenorphine for pain management in children

open access: yesDrugs in Context, 2021
Pain is one of the main symptoms reported by sick children, particularly by those suffering from cancer. Opioids are very useful in controlling this symptom but they are burdened with significant side effects that limit their use in children ...
Giorgio Attinà   +5 more
doaj   +1 more source

Microneedle-assisted genome editing: A transdermal strategy of targeting NLRP3 by CRISPR-Cas9 for synergistic therapy of inflammatory skin disorders

open access: yesScience Advances, 2021
Transdermal delivery of genome-editing agents by microneedle promotes the glucocorticoid therapy of inflammatory skin disorders. We report a dissolvable microneedle (MN) patch that can mediate transdermal codelivery of CRISPR-Cas9–based genome-editing ...
Tao Wan, Qi Pan, Yuan Ping
semanticscholar   +1 more source

Effect of Crosslinking Agent Concentration on the Properties of Unmedicated Hydrogels

open access: yesPharmaceutics, 2015
Novel polyethylene oxide (PEO) hydrogel films were synthesized via UV crosslinking with varying concentrations of pentaerythritol tetra-acrylate (PETRA) as crosslinking agent.
Rachel Shet Hui Wong   +2 more
doaj   +1 more source

Transdermal electroosmotic flow generated by a porous microneedle array patch

open access: yesNature Communications, 2021
A microneedle array is an attractive option for a minimally invasive means to break through the skin barrier for efficient transdermal drug delivery.
Shinya Kusama   +6 more
semanticscholar   +1 more source

Angiotensin-Neprilysin Inhibitor Therapy: A Retrospective Chart Study

open access: yesINNOVATIONS in Pharmacy
Background: Guideline-directed medical therapy in patients with systolic heart failure (HF) has demonstrated improvement in morbidity and mortality rates.
Roda Plakogiannis   +3 more
doaj   +1 more source

Current trends in polymer microneedle for transdermal drug delivery

open access: yesInternational journal of pharmaceutics, 2020
Graphical abstract Polymer microneedle promotes the delivery of chemical and biological drugs through the skin.
Khater Ahmed Saeed Al-Japairai   +6 more
semanticscholar   +1 more source

Safety of opioid patch initiation in Australian residential aged care [PDF]

open access: yes, 2015
Explores opioid use by aged care facility residents before and after initiation of transdermal opioid patches. Abstract Objective: To explore opioid use by aged care facility residents before and after initiation of transdermal opioid patches. Design:
Lisa Pont   +5 more
core   +1 more source

Continuous Drug Release by Sea Anemone Nematostella vectensis Stinging Microcapsules

open access: yesMarine Drugs, 2014
Transdermal delivery is an attractive option for drug delivery. Nevertheless, the skin is a tough barrier and only a limited number of drugs can be delivered through it. The most difficult to deliver are hydrophilic drugs.
Yossi Tal   +5 more
doaj   +1 more source

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