Results 71 to 80 of about 55,857 (266)

Fractal Model of Transdermal Drug Delivery

open access: yes, 2018
Skin, separating the vital organs of a human body, is a desirable route for drug delivery. However, the intact skin is normally permeable only for drug molecules with a low molecular weight. The stratum corneum (SC), being the outermost layer of the skin
Iwanowska-Chomiak, B.   +3 more
core   +1 more source

A Review on Catalytic Nanostructured Electrodes for Wearable and Implantable Abiotic Glucose Fuel Cells

open access: yesAdvanced Science, EarlyView.
This review identifies current and future directions in abiotic nanostructured catalysts to develop reliable and sustainable glucose fuel cells to power the next generation of bioelectronic devices. ABSTRACT The global rise in incidence of chronic diseases has led to the demand for innovative solutions that help patients manage their conditions with ...
Asghar Niyazi   +3 more
wiley   +1 more source

Transdermal drug delivery of labetalol hydrochloride: Feasibility and effect of penetration enhancers

open access: yesJournal of Pharmacy and Bioallied Sciences, 2010
Objectives : The objective of this study is to investigate the feasibility of transdermal drug delivery of Labetalol Hydrochloride (LHCl) and to study the effect of different penetration enhancers on the skin permeability of LHCl.
Saqib Zafar   +3 more
doaj   +1 more source

Modeling of Smart Bio-Medical Active Polymeric Hydrogel Transdermal Materials

open access: yes
In this article, effective 3D printing modeling technology of smart bio-medical polymeric hydrogel transdermal materials based on gelatin and sodium alginate, modified by humic acids, was researched.
Masikevych A. Y.   +5 more
core   +1 more source

The role of transdermal estrogen sprays and estradiol topical emulsion in the management of menopause-associated vasomotor symptoms

open access: yes, 2010
Amy M Egras, Elena M UmlandJefferson School of Pharmacy, Thomas Jefferson University, Philadelphia, PA, USAAbstract: Vasomotor symptoms (VMS) are among the most bothersome complaints of postmenopausal women. To date, the most widely studied and effective
Amy M Egras   +5 more
core   +1 more source

Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy

open access: yesAdvanced Science, EarlyView.
Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee   +11 more
wiley   +1 more source

Dendrimers for Drug Delivery

open access: yesMolecules, 2018
Dendrimers have come a long way in the last 25 years since their inception. Originally created as a wonder molecule of chemistry, dendrimer is now in the fourth class of polymers. Dr.
Abhay Singh Chauhan
doaj   +1 more source

Pharmacokinetic studies for the development of transdermal drug delivery systems

open access: yes, 2007
PhDThis thesis mainly describes a series of Phase I pharmacokinetic studies conducted on the TDS®d elivery systemw hich combinedw ith lidocaine,t estosteronea, nd a new drug, Melanotan-I for the transdermal drug delivery.
Chik, Zamri
core  

Highly Biomimetic Ectodermal Epithelial Organoids for Epithelial Barrier Stimulation Assays

open access: yesAdvanced Science, EarlyView.
ABSTRACT Evaluating the potential toxicity of pharmaceuticals and biomaterials to ectodermal epithelia, such as the oral mucosa and skin, is indispensable in pre‐clinical assessments. However, this remains a challenge primarily owing to the lack of physiologically relevant and accurate screening models.
Yiming Chen   +13 more
wiley   +1 more source

Globular and Fibrous Proteins Modified with Deep Eutectic Solvents: Materials for Drug Delivery

open access: yesMolecules, 2019
Proteinaceous materials have numerous structures, many of which aid in the roles they perform. Some need to impart strength while others need elasticity or toughness.
Wanwan Qu   +4 more
doaj   +1 more source

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